HIV-1 and two avian retroviral 5' untranslated regions bind orthologous human and chicken RNA binding proteins.

abstract：:Mouse hybridomas which produce monoclonal antibodies to the Autographa californica nuclear polyhedrosis virus (AcNPV) have been prepared and the protein to which each is directed has been determined. The antibody produced by clones 3F3 and 5E9 specifically bound polyhedron protein of MW 32,000 when used in immunoadsor...

journal_title：Virology

authors： Roberts PL,Naser W

更新日期：1982-10-30 00:00:00

abstract：:The genome of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) contains four structural genes that are homologous to genes found in other coronaviruses, and also contains six subgroup-specific open reading frames (ORFs). Expression of one of these subgroup-specific genes, ORF7a, resulted in apoptosi...

journal_title：Virology

authors： Yuan X,Wu J,Shan Y,Yao Z,Dong B,Chen B,Zhao Z,Wang S,Chen J,Cong Y

更新日期：2006-03-01 00:00:00

abstract：:To study the role of human papillomavirus (HPV) infection in the development of genetic instability, we transduced normal human airway and anogenital epithelial cells with various combinations of HPV-16 E6, E7, and the reverse transcriptase component of telomerase (hTERT). Cell lines generated by co-expression of E7 w...

journal_title：Virology

authors： Klingelhutz AJ,Qian Q,Phillips SL,Gourronc FA,Darbro BW,Patil SR

更新日期：2005-09-30 00:00:00

abstract：:Abnormal reinitiation of replication from lambda origins has previously been found during infection in the presence of caffeine or cis-diamminedichloroplatinum II (cis-Pt) or when lambda infects a P2 lysogen. It was further shown that the reinitiations arising from cis-Pt treatment took place during the SOS response i...

journal_title：Virology

authors： Schnös M,Inman RB

更新日期：1987-06-01 00:00:00

abstract：:Morphological and molecular changes produced by Autographa californica nuclear polyhedrosis virus (AcMNPV) infection in a permissive cell line, IPLB-SF-21AE (SF-21), of Spodoptera frugiperda and a nonpermissive cell line, FPMI-CF-203 (CF-203), of Choristoneura fumiferana are described. CF-203 cells inoculated with AcM...

journal_title：Virology

authors： Palli SR,Caputo GF,Sohi SS,Brownwright AJ,Ladd TR,Cook BJ,Primavera M,Arif BM,Retnakaran A

更新日期：1996-08-01 00:00:00

abstract：:The caprine arthritis-encephalitis (CAEV) and ovine maedi-visna (MVV) viruses are resistant to antibody neutralization, a feature shared with all other lentiviruses. Whether the CAEV gp135 receptor binding site(s) (RBS) in the functional surface envelope glycoprotein (Env) is protected from antibody binding, allowing ...

journal_title：Virology

authors： Hötzel I,Cheevers WP

更新日期：2005-09-01 00:00:00

abstract：:An emv-14-derived, replication-competent ecotropic murine leukemia virus [MuLV], designated AK7, was previously cloned from the AKXL-5 recombinant inbred mouse strain and partially characterized. While genetically encoding for an envelope-derived immunodominant CTL epitope [KSPWFTTL] located in the transmembrane regio...

journal_title：Virology

authors： Kim V,Green WR

更新日期：1997-09-29 00:00:00

abstract：:Human adenovirus type 3 (HAdV-B3) has an apparently stable genome yet remains a major circulating and problematic respiratory pathogen. Comparisons of the prototype genome to genomes from three current field strains, including two isolated from epidemics, and a laboratory strain, yielded small-scale nucleotide variati...

journal_title：Virology

authors： Mahadevan P,Seto J,Tibbetts C,Seto D

更新日期：2010-02-05 00:00:00

abstract：:An ideal system to investigate individual determinants of the replication process of (+)-strand RNA viruses is a cell-free extract that supports viral protein and RNA synthesis in a synchronized manner. Here, we applied a translation/replication system based on cytoplasmic extracts of Nicotiana tabacum cells to Tomato...

journal_title：Virology

authors： Gursinsky T,Schulz B,Behrens SE

更新日期：2009-08-01 00:00:00

abstract：:HTLV-I infection is characterized by low viremia and restricted viral expression. While the mechanisms regulating viral latency are poorly understood, it is believed that interactions between viral and host cellular factor(s) are involved. Several lines of evidence indicate that HTLV-I provirus may be methylated in pr...

journal_title：Virology

authors： Saggioro D,Forino M,Chieco-Bianchi L

更新日期：1991-05-01 00:00:00

abstract：:Previous studies indicated that hepatitis C virus core protein influences cellular apoptosis. However, the precise mechanisms of the effects are not fully understood. Therefore, in this study, we examined the mechanisms of the effects on cell apoptosis by core protein, using transiently transfected and magnetically co...

journal_title：Virology

authors： Otsuka M,Kato N,Taniguchi H,Yoshida H,Goto T,Shiratori Y,Omata M

更新日期：2002-04-25 00:00:00

abstract：:Infectious pancreatic necrosis is an important viral disease of salmonid fish reared in hatchery. Its etiological agent, IPNV, showed a high degree of antigenic heterogeneity. Up to 10 serotypes and 2 serogroups were proposed. Yet, very little is known about genomic variations among viruses of different origin. In ord...

journal_title：Virology

authors： Heppell J,Berthiaume L,Corbin F,Tarrab E,Lecomte J,Arella M

更新日期：1993-08-01 00:00:00

abstract：:Alphaviruses are mosquito-borne viruses that cause serious human and animal diseases. Previous studies demonstrated that a determinant within the nsP1/nsP2 cleavage domain of the virulent Sindbis AR86 virus played a key role in regulating adult mouse virulence without adversely affecting viral replication. Additional ...

journal_title：Virology

authors： Cruz CC,Suthar MS,Montgomery SA,Shabman R,Simmons J,Johnston RE,Morrison TE,Heise MT

更新日期：2010-03-30 00:00:00

abstract：:The 64K surface protein of budded Autographa californica nuclear polyhedrosis virus (AcMNPV BV) is known to play a role in the functional entry of AcMNPV BV into Spodoptera frugiperda IPLB-SF-21 cells by adsorptive endocytosis. AcV1, a neutralizing monoclonal antibody, reacts with the 64K protein and in doing so preve...

journal_title：Virology

authors： Volkman LE,Goldsmith PA

更新日期：1988-09-01 00:00:00

abstract：:Neutralizing antibodies (Nabs) are thought to play an important role in prevention and control of HIV-1 infection and should be targeted by an AIDS vaccine. It is critical to understand how HIV-1 induces Nabs by analyzing viral sequences in both tested viruses and sera. Neutralization susceptibility to antibodies in a...

journal_title：Virology

authors： Kirchherr JL,Hamilton J,Lu X,Gnanakaran S,Muldoon M,Daniels M,Kasongo W,Chalwe V,Mulenga C,Mwananyanda L,Musonda RM,Yuan X,Montefiori DC,Korber BT,Haynes BF,Gao F

更新日期：2011-01-20 00:00:00

abstract：:Nanogram amounts of the proinflammatory cytokine interleukin-1alpha (IL-1alpha) were detected in uninfected cultures of human corneal epithelial cells (HCEC). Although HSV-1 replicated >10(4)-fold in these cells and caused extensive cytopathic effects, virus infection was not accompanied by significant extracellular r...

journal_title：Virology

authors： Tran MT,Dean DA,Lausch RN,Oakes JE

更新日期：1998-04-25 00:00:00

abstract：:Human immunodeficiency virus (HIV) encodes a transacting protein, Rev, which interacts with an RNA element (RRE) to mediate nuclear export of unspliced viral mRNA. Recently, the RNA constitutive transport elements (CTE) from Mason-Pfizer monkey virus (MPMV) and simian retrovirus type I (SRV-1) were shown to render Rev...

journal_title：Virology

authors： Tang H,Xu Y,Wong-Staal F

更新日期：1997-02-17 00:00:00

abstract：:Ovine pulmonary carcinoma, a contagious lung cancer of sheep, is caused by the oncogenic jaagsiekte sheep retrovirus (JSRV) that is closely related to a family of endogenous sheep retroviral sequences (ESRVs). By using exogenous virus-specific U3 oligonucleotide primers, the entire JSRV proviral genome or its 3' part ...

journal_title：Virology

authors： Bai J,Bishop JV,Carlson JO,DeMartini JC

更新日期：1999-06-05 00:00:00

abstract：:We describe the in vitro selection and characterisation of virus derived from B/Beijing/1/87 passaged in the presence of zanamivir. During zanamivir passage, the phenotype of virus isolates was either drug dependent or drug resistant in plaque reduction assays. The susceptibility of the neuraminidase of the drug-depen...

journal_title：Virology

authors： Barnett JM,Cadman A,Burrell FM,Madar SH,Lewis AP,Tisdale M,Bethell R

更新日期：1999-12-20 00:00:00

abstract：:The HIV-1 accessory gene product Vpr can inhibit cell proliferation via cell cycle arrest at the G(2) phase, and it can induce apoptosis after G(2) arrest. We found recently that C81, a carboxy-terminally truncated form of Vpr, induced apoptosis via G(1) arrest but did not induce G(2) arrest of the cell cycle. Thus, i...

journal_title：Virology

authors： Nishizawa M,Kamata M,Mojin T,Nakai Y,Aida Y

更新日期：2000-10-10 00:00:00

abstract：:The 30K protein of tobacco mosaic virus was recently confirmed to be involved in cell-to-cell movement of the virus. To characterize common structural features of the 30K protein, the nucleotide sequence of the 30K protein gene of cucumber green mottle mosaic virus (CGMMV, a member of the tobamoviruses) RNA has been d...

journal_title：Virology

authors： Saito T,Imai Y,Meshi T,Okada Y

更新日期：1988-12-01 00:00:00

abstract：:The rep gene of the defective human parvovirus, adeno-associated virus, (AAV) mediates several trans-acting functions important to virus replication, transcription, and gene expression. At least four overlapping polypeptides are expressed from the rep gene. We have constructed a prokaryotic vector which expressed in E...

journal_title：Virology

authors： Trempe JP,Mendelson E,Carter BJ

更新日期：1987-11-01 00:00:00

abstract：:Adenoviruses (Ads) infect hosts from all vertebrate species and have been investigated as vaccine vectors. We report here near-atomic structures of two bovine Ad type 3 (BAd3) intermediates obtained by cryo-electron microscopy. A comparison between the two intermediate structures reveals that the differences are local...

journal_title：Virology

authors： Cheng L,Huang X,Li X,Xiong W,Sun W,Yang C,Zhang K,Wang Y,Liu H,Huang X,Ji G,Sun F,Zheng C,Zhu P

更新日期：2014-02-01 00:00:00

abstract：:EBNA-1 is the sole virally specified protein required for replication of the Epstein-Barr virus latency origin and also modulates its own expression. Both of these functions are mediated through specific DNA binding. We created a series of amino acid substitutions across the previously identified DNA-binding domain of...

journal_title：Virology

authors： Chen MR,Zong J,Hayward SD

更新日期：1994-12-01 00:00:00

abstract：:Feline calicivirus depends on host-cell proteins for its replication. We previously showed that knockdown of nucleolin (NCL), a phosphoprotein involved in ribosome biogenesis, resulted in the reduction of FCV protein synthesis and virus yield. Here, we found that NCL may not be involved in FCV binding and entry into c...

journal_title：Virology

authors： Hernández BA,Sandoval-Jaime C,Sosnovtsev SV,Green KY,Gutiérrez-Escolano AL

更新日期：2016-02-01 00:00:00

abstract：:All primates studied to date produce retroviral-like particles in their placentae. We have purified these particles from two primate species, one Old World (human) and one New World (marmoset), and have identified the retroviral sequences which are packaged into these particles. Three families of sequences have been d...

journal_title：Virology

authors： Simpson GR,Patience C,Löwer R,Tönjes RR,Moore HD,Weiss RA,Boyd MT

更新日期：1996-08-15 00:00:00

abstract：:The P670 promoter of HPV16 directs transcription of the virus late genes in the differentiating epithelium. We found that CCAAT/enhancer binding protein beta (C/EBPbeta), a key transcription factor that induces the terminal differentiation of keratinocytes, enhanced the P670-driven transcription in transient reporter ...

journal_title：Virology

authors： Kukimoto I,Takeuchi T,Kanda T

更新日期：2006-03-01 00:00:00

abstract：:Coxsackievirus B4 (CBV4), a member of the Picornavirus genus, has long been implicated in the development of insulin-dependent diabetes mellitus (IDDM), by viral-induced pancreatic cell damage. Although the pancreotropic nature of this virus is well documented, the early stages of CBV4 viral infection that involve the...

journal_title：Virology

authors： Triantafilou K,Triantafilou M

更新日期：2004-08-15 00:00:00

abstract：:The minute virus of mice, prototype strain (MVMp), is a non-enveloped, single-stranded DNA virus of the family Parvoviridae. Unlike other parvoviruses, the mechanism of cellular uptake of MVMp has not been studied in detail. We analyzed MVMp endocytosis in mouse LA9 fibroblasts and a tumor cell line derived from epith...

journal_title：Virology

authors： Garcin PO,Panté N

更新日期：2015-08-01 00:00:00

abstract：:In order to determine the location and biological significance of the acid-induced conformational change in influenza virus hemagglutinin (HA) reported by Skehel et al., monoclonal antibodies were prepared to the molecule before and after treatment at pH 5.0. These antibodies together with monoclonal antibodies to the...

journal_title：Virology

authors： Webster RG,Brown LE,Jackson DC

更新日期：1983-04-30 00:00:00