Abstract:
:The tumor microenvironment is known to play an important role in tumorigenesis. In this issue, Yang et al. (2008) demonstrate that mast cells heterozygous for the Nf1 gene promote the growth of neurofibromas in a mouse model of neurofibromatosis and that genetic and pharmacological inhibition of these cells is sufficient to block tumor growth.
journal_name
Celljournal_title
Cellauthors
Reilly KM,Van Dyke Tdoi
10.1016/j.cell.2008.10.009subject
Has Abstractpub_date
2008-10-31 00:00:00pages
408-10issue
3eissn
0092-8674issn
1097-4172pii
S0092-8674(08)01299-3journal_volume
135pub_type
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