Cortical hypoperfusion in the B6.PS2APP mouse model for Alzheimer's disease: comprehensive phenotyping of vascular and tissular parameters by MRI.

abstract：:Kinetic analysis with mathematical models has become increasingly important to quantify physiological parameters in computed tomography (CT), positron emission tomography (PET), and dynamic contrast-enhanced MRI (DCE-MRI). The modified Kety/Tofts model and the graphical (Patlak) model have been widely applied to DCE-M...

journal_title：Magnetic resonance in medicine

authors： Chen H,Li F,Zhao X,Yuan C,Rutt B,Kerwin WS

更新日期：2011-09-01 00:00:00

abstract：:Black blood MRI is an attractive tool for monitoring normal and pathological wall thickening; however, limited spatial resolutions can conspire with complex vascular geometries to distort the appearance of the wall in ways hitherto unclear. To elucidate this, a thin-walled cylinder model was developed to predict the c...

journal_title：Magnetic resonance in medicine

authors： Antiga L,Wasserman BA,Steinman DA

更新日期：2008-11-01 00:00:00

abstract：:Variable nutation SSFP (DESPOT2) permits rapid, high-resolution determination of the transverse (T2) relaxation constant. A limitation of DESPOT2, however, is the presence of T2 voids due to off-resonance banding artifacts associated with SSFP images. These artifacts typically occur in images acquired with long repeti...

journal_title：Magnetic resonance in medicine

authors： Deoni SC,Ward HA,Peters TM,Rutt BK

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:To demonstrate the feasibility of imaging the first passage of a bolus of hyperpolarized (13)C urea through the rodent heart using flow-sensitizing gradients to reduce signal from the blood pool. METHODS:A flow-sensitizing bipolar gradient was optimized to reduce the bright signal within the cardiac chambers, ...

journal_title：Magnetic resonance in medicine

authors： Lau AZ,Miller JJ,Robson MD,Tyler DJ

更新日期：2016-04-01 00:00:00

abstract：:The study of brain function using MRI relies on acquisition techniques that are sensitive to different aspects of the hemodynamic response contiguous to areas of neuronal activity. For this purpose different contrasts such as arterial spin labeling (ASL) and blood oxygenation level dependent (BOLD) functional MRI tech...

journal_title：Magnetic resonance in medicine

authors： Woolrich MW,Chiarelli P,Gallichan D,Perthen J,Liu TT

更新日期：2006-10-01 00:00:00

abstract：:We present preliminary results for a 3D finite element calculation to evaluate RF penetration in conducting dielectric materials at high field strengths. A tetrahedral mesh is used along with a Coulomb gauge constraint in a finite element method that yields excellent numerical stability at high frequencies. Accuracy i...

journal_title：Magnetic resonance in medicine

authors： Petropoulos LS,Haacke EM,Brown RW,Boerner E

更新日期：1993-09-01 00:00:00

abstract：:Cell death by apoptosis is critical in myocardial diseases, and noninvasive detection of early, reversible apoptosis might be useful clinically. Exogenous Annexin-V (ANX) protein binds membrane phosphatidylserine, which is externalized in early apoptosis. A molecular MRI probe was constructed with superparamagnetic ir...

journal_title：Magnetic resonance in medicine

authors： Dash R,Chung J,Chan T,Yamada M,Barral J,Nishimura D,Yang PC,Simpson PC

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:The goal of this work was to detect disease-related microstructural changes to the liver using magnetic resonance imaging. Chronic liver disease can cause microstructural changes in the liver that reduce plasma access to the perisinusoidal space--the site of exchange between the blood plasma and the hepatic par...

journal_title：Magnetic resonance in medicine

authors： Beeman SC,Mandarino LJ,Georges JF,Bennett KM

更新日期：2013-12-01 00:00:00

abstract：:Partial-volume effects (PVE) in stroke imaging could hinder proper delineation of normal, ischemic, and at-risk tissues. Cerebral-blood-flow (CBF) and apparent diffusion coefficient (ADC) were measured at high and low resolution (HR = 128 x 128, LR = 64 x 64) in focal ischemia in rats during the acute phase. The data ...

journal_title：Magnetic resonance in medicine

authors： Ren H,Shen Q,Bardutzky J,Fisher M,Duong TQ

更新日期：2004-12-01 00:00:00

abstract：:A deficit of fatty alcohol:NAD+ oxidoreductase complex (FAO) activity has been detected in patients with the Sjögren-Larsson syndrome (SLS). A moderate decrease in FAO activity has also been reported in heterozygote SLS subjects. Abnormal peaks were detected with proton magnetic resonance spectroscopy (1H-MRS) in homo...

journal_title：Magnetic resonance in medicine

authors： Kaminaga T,Mano T,Ono J,Kusuoka H,Nakamura H,Nishimura T

更新日期：2001-06-01 00:00:00

abstract：:Steady-state free precession (SSFP) methods have gained widespread recognition for their ability to provide fast scans at high signal-to-noise ratio. This paper demonstrates that such methods are also capable of reflecting functional information, particularly blood oxygenation state. It is well known that SSFP signals...

journal_title：Magnetic resonance in medicine

authors： Dharmakumar R,Hong J,Brittain JH,Plewes DB,Wright GA

更新日期：2005-03-01 00:00:00

abstract：:A novel method for reducing the rf power requirements of selective pulses employed for z magnetization slice inversion in localized NMR spectroscopy is presented. Following slice preparation by the use of frequency-incremented sinc pulses, the slice gradient is reduced, which narrows the frequency width of the slice. ...

journal_title：Magnetic resonance in medicine

authors： Brereton IM,Brooks WM,Marshman MF,Field J,Doddrell DM

更新日期：1987-12-01 00:00:00

abstract：PURPOSE:To develop a three-dimensional, free-breathing, late gadolinium enhancement (3D FB-LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two-dimensional breath-hold LGE (2D BH-LGE). METHODS:The proposed 3D FB-LGE method consisted of inversion preparation, inversion dela...

journal_title：Magnetic resonance in medicine

authors： Menon RG,Miller GW,Jeudy J,Rajagopalan S,Shin T

更新日期：2017-04-01 00:00:00

abstract：:Dynamic contrast-enhanced (DCE-) MRI is often used to evaluate the response to experimental antiangiogenic therapies in small animal models of cancer. Unfortunately, DCE-MRI studies often require a substantial investment of both time and money to achieve the desired level of statistical significance. Multiple-mouse MR...

journal_title：Magnetic resonance in medicine

authors： Ramirez MS,Ragan DK,Kundra V,Bankson JA

更新日期：2007-09-01 00:00:00

abstract：:Magnetic field homogeneity is of major concern for in vivo spectroscopy, and with the increased use of volumetric chemical shift imaging (CSI) techniques, the ability to shim over a large volume of tissue is now one of the primary limiting constraints in performing these studies. In vivo shimming is routinely performe...

journal_title：Magnetic resonance in medicine

authors： Spielman DM,Adalsteinsson E,Lim KO

更新日期：1998-09-01 00:00:00

abstract：:A stimulated echo sequence was used to obtain 19F NMR spectra from within a 4-ml voxel in a cat brain. The time dependence of the 19F NMR signal from an inert gas (CHF3) was used to calculate the blood flow in the voxel. The position of the voxel was selected using a 1H MR image. ...

journal_title：Magnetic resonance in medicine

authors： van Zijl PC,Ligeti L,Sinnwell T,Alger JR,Chesnick AS,Moonen CT,McLaughlin AC

更新日期：1990-12-01 00:00:00

abstract：PURPOSE:We incorporate simultaneous multislice (SMS) acquisition into MR fingerprinting (MRF) to accelerate the MRF acquisition. METHODS:The t-Blipped SMS-MRF method is achieved by adding a Gz blip before each data acquisition window and balancing it with a Gz blip of opposing polarity at the end of each TR. Thus the ...

journal_title：Magnetic resonance in medicine

authors： Ye H,Ma D,Jiang Y,Cauley SF,Du Y,Wald LL,Griswold MA,Setsompop K

更新日期：2016-05-01 00:00:00

abstract：:The prebolus technique allows one to quantify perfusion in the human heart with a low variability by means of MRI. In this study the prebolus technique was used to determine quantitative perfusion values in the human heart under adenosine stress and to measure the myocardial perfusion reserve (MPR). Twelve healthy vol...

journal_title：Magnetic resonance in medicine

authors： Ritter C,Brackertz A,Sandstede J,Beer M,Hahn D,Köstler H

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:Establishing a framework to evaluate performances of prospective motion correction (PMC) MRI considering motion variability between MRI scans. METHODS:A framework was developed to obtain quantitative comparisons between different motion correction setups, considering that varying intrinsic motion patterns betw...

journal_title：Magnetic resonance in medicine

authors： Pannetier NA,Stavrinos T,Ng P,Herbst M,Zaitsev M,Young K,Matson G,Schuff N

更新日期：2016-02-01 00:00:00

abstract：:The spin-lattice relaxation time T1 of multicomponent tissues is often determined by fitting relaxation data to monoexponential functions. This process can lead to large errors in the relaxation time. We describe a procedure using chemical-shift imaging (CSI) which separates the NMR signal into water and lipid compone...

journal_title：Magnetic resonance in medicine

authors： Hornak JP,Smith AC,Szumowski J

更新日期：1990-03-01 00:00:00

abstract：PURPOSE:Spatio-temporal encoding (SPEN) experiments can deliver single-scan MR images without folding complications and with robustness to chemical shift and susceptibility artifacts. Further resolution improvements are shown to arise by relying on multiple receivers, to interpolate the sampled data along the low-bandw...

journal_title：Magnetic resonance in medicine

authors： Liberman G,Solomon E,Lustig M,Frydman L

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To examine the detection sensitivity for the rapidly exchanging hydroxyl protons of D-glucose using the recently developed on-resonance variable delay multi-pulse (onVDMP) chemical exchange saturation transfer (CEST) technique. METHODS:The onVDMP method was applied for the detection of water signal changes upo...

journal_title：Magnetic resonance in medicine

authors： Xu X,Xu J,Chan KWY,Liu J,Liu H,Li Y,Chen L,Liu G,van Zijl PCM

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:Myocardial blood-flow simulation based on laws of fluid mechanics is a valuable tool for understanding tissue behavior. Our aim is to evaluate the ability of a porous-media flow model approach to reflect disturbed washout of contrast media (CM) from the myocardium as observed by cardiovascular MR. METHODS:A co...

journal_title：Magnetic resonance in medicine

authors： Riazy L,Schaeffter T,Olbrich M,Schueler J,von Knobelsdorff-Brenkenhoff F,Niendorf T,Schulz-Menger J

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To develop and evaluate a novel two-dimensional self-gated imaging technique for free-breathing cardiac cine MRI that is free of motion-detection overhead and requires minimal planning for motion tracking. METHODS:Motion along the readout direction was extracted solely from normal Cartesian imaging readouts ne...

journal_title：Magnetic resonance in medicine

authors： Guo L,Derbyshire JA,Herzka DA

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To develop a method to correct for geometric distortions in non-Cartesian echo planar imaging using data acquired in a fast prescan. METHODS:Echo planar images were obtained using a non-Cartesian density weighted k-space trajectory. In contrast to linear Cartesian acquisition, distortions arising in non-Cartes...

journal_title：Magnetic resonance in medicine

authors： Zeller M,Müller A,Hahn D,Köstler H

更新日期：2014-03-01 00:00:00

abstract：:It is shown that in vivo measurement of bile water apparent diffusion coefficient (ADC) by diffusion-weighted echo-planar imaging (EPI) in hamster gallbladder is possible providing motion artifact-free ADC values. These ADC values are used to estimate bile viscosity variation induced by normal diets, cholesterol galls...

journal_title：Magnetic resonance in medicine

authors： Tiffon B,Parquet M,Dubrac S,Lutton C,Volk A

更新日期：2000-06-01 00:00:00

abstract：:The combination of an in-plane B(1) sensitivity encoding (SENSE) technique with a simultaneous multiple-slice B(0) field step technique (multiple-acquisition micro B(0) array (MAMBA)) has produced high scan time reduction factors (R < or = 8). In this study, two slices were acquired simultaneously in combination with ...

journal_title：Magnetic resonance in medicine

authors： Paley MN,Lee KJ,Wild JM,Fichele S,Whitby EH,Wilkinson ID,Van Beek EJ,Griffiths PD

更新日期：2003-06-01 00:00:00

abstract：:In this study we utilized manganese-enhanced MRI (MEMRI) to evaluate the in vivo transneuronal efficiency of manganese ion (Mn(2+)) movement as a means to assess overall changes in neuronal function. We designated this extension the manganese transfer index (MTI) value. To evaluate the MTI value as an index of transne...

journal_title：Magnetic resonance in medicine

authors： Serrano F,Deshazer M,Smith KD,Ananta JS,Wilson LJ,Pautler RG

更新日期：2008-07-01 00:00:00

abstract：:The accurate assessment of pulmonary perfusion is especially important in the evaluation of patients with suspected pulmonary embolism, a common and potentially lethal disorder that can be treated by aggressive anticoagulation. In this study, we demonstrate for the first time the use of MR to image pulmonary perfusion...

journal_title：Magnetic resonance in medicine

authors： Hatabu H,Gaa J,Kim D,Li W,Prasad PV,Edelman RR

更新日期：1996-10-01 00:00:00

abstract：:A modified Prony method (MPM) was applied to analyze the main signals present in spatially resolved 31P NMR spectra of MCF7 breast tumors implanted in nude mice. First, the method was tested on synthetic data to establish its limits of reliability. Its performance with respect to peak identification and quantification...

journal_title：Magnetic resonance in medicine

authors： Viti V,Ragona R,Guidoni L,Barone P,Furman E,Degani H

更新日期：1997-08-01 00:00:00