Quantitative assessment of improved homogeneity using higher-order shims for spectroscopic imaging of the brain.

Abstract:

:Magnetic field homogeneity is of major concern for in vivo spectroscopy, and with the increased use of volumetric chemical shift imaging (CSI) techniques, the ability to shim over a large volume of tissue is now one of the primary limiting constraints in performing these studies. In vivo shimming is routinely performed using linear shim correction terms, and although many scanners are also equipped with additional resistive shim supplies that can provide second and third-order shim fields, they are often not used due to the additional effort and scan time required. The question as to how much improvement can be achieved using additional higher-order shims compared with the linear shims alone was quantitatively addressed. Performance measures for both intervoxel B0 uniformity and intravoxel T2* line broadening were evaluated for 15 normal volunteers. The analysis tools developed in this study, along with the summarized data, can be useful in deciding if a given application warrants the additional time, effort, and expense (if additional hardware needs to be purchased) of implementing higher-order shimming routines. For CSI studies of the brain, the use of the higher-order shims, compared with linear terms alone, yielded approximately 30% greater volume of brain tissue that could be shimmed within typical constraints for intervoxel B0 shifts and intravoxel T2* linebroadening. In addition, a regional analysis shows significant improvement in the homogeneity within specific areas of the brain, particularly those near the skull.

journal_name

Magn Reson Med

authors

Spielman DM,Adalsteinsson E,Lim KO

doi

10.1002/mrm.1910400307

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

376-82

issue

3

eissn

0740-3194

issn

1522-2594

journal_volume

40

pub_type

杂志文章
  • A high-field superferric NMR magnet.

    abstract::Strong, extensive magnetic fringe fields are a significant problem with magnetic resonance imaging magnets. This is particularly acute with 4-T, whole-body research magnets. To date this problem has been addressed by restricting an extensive zone around the unshielded magnet or by placing external unsaturated iron shi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910290107

    authors: Huson FR,Bryan RN,MacKay WW,Herrick RC,Colvin J,Ford JJ,Pissanetzky S,Plishker GA,Rocha R,Schmidt W

    更新日期:1993-01-01 00:00:00

  • Dysprosium-bearing red cells as potential transverse relaxation agents for MRI.

    abstract::The cytosol of intact human red blood cells was loaded with 28.1 +/- 3.4 mM of dysprosium DTPA-BMA using a hypoosmotic technique. When loaded cells were diluted with saline and control cells to give an average dysprosium concentration of 3.3 +/- 0.5 mM, the transverse relaxation rate constants R(*)(2) and R(2) increas...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1122

    authors: Johnson KM,Tao JZ,Kennan RP,Gore JC

    更新日期:2001-05-01 00:00:00

  • Quantitative MRI of Gd-DTPA uptake in tumors: response to photodynamic therapy.

    abstract::A partial saturation method is described for obtaining rapid images of tissue 1H spin-lattice relaxation rates following administration of the paramagnetic contrast agent gadolinium-diethylenetriaminepentaacetate. The paramagnetic contribution to the relaxation rates is proportional to the concentration of contrast ag...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910310308

    authors: Kennedy SD,Szczepaniak LS,Gibson SL,Hilf R,Foster TH,Bryant RG

    更新日期:1994-03-01 00:00:00

  • Kinetic modeling of hyperpolarized (13)C pyruvate metabolism in tumors using a measured arterial input function.

    abstract::Mathematical models are required to estimate kinetic parameters of [1-(13)C] pyruvate-lactate interconversion from magnetic resonance spectroscopy data. One- or two-way exchange models utilizing a hypothetical approximation to the true arterial input function (AIF), (e.g. an ideal 'box-car' function) have been used pr...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24546

    authors: Kazan SM,Reynolds S,Kennerley A,Wholey E,Bluff JE,Berwick J,Cunningham VJ,Paley MN,Tozer GM

    更新日期:2013-10-01 00:00:00

  • Fast diffusion imaging with high angular resolution.

    abstract:PURPOSE:High angular resolution diffusion imaging (HARDI) is a well-established method to help reveal the architecture of nerve bundles, but long scan times and geometric distortions inherent to echo planar imaging (EPI) have limited its integration into clinical protocols. METHODS:A fast imaging method is proposed he...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26163

    authors: Chao TC,Chiou JG,Maier SE,Madore B

    更新日期:2017-02-01 00:00:00

  • Double-echo three-point-Dixon method for fat suppression MRI.

    abstract::A double-echo two-excitation pulse sequence encoding fat and water signals for a phase-sensitive three-point Dixon-type analysis (DE-3PD) was developed and implemented on a 1.5 T MR imager. Data processing was performed using a previously developed two-dimensional (2D) region-growing algorithm, adapted to use double-e...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910340118

    authors: Szumowski J,Coshow W,Li F,Coombs B,Quinn SF

    更新日期:1995-07-01 00:00:00

  • Signal-to-noise ratio and spectral linewidth improvements between 1.5 and 7 Tesla in proton echo-planar spectroscopic imaging.

    abstract::This study characterizes gains in sensitivity and spectral resolution of proton echo-planar spectroscopic imaging (PEPSI) with increasing magnetic field strength (B(0)). Signal-to-noise ratio (SNR) per unit volume and unit time, and intrinsic linewidth (LW) of N-acetyl-aspartate (NAA), creatine (Cr), and choline (Cho)...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21067

    authors: Otazo R,Mueller B,Ugurbil K,Wald L,Posse S

    更新日期:2006-12-01 00:00:00

  • The importance of correcting for signal drift in diffusion MRI.

    abstract:PURPOSE:To investigate previously unreported effects of signal drift as a result of temporal scanner instability on diffusion MRI data analysis and to propose a method to correct this signal drift. METHODS:We investigated the signal magnitude of non-diffusion-weighted EPI volumes in a series of diffusion-weighted imag...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26124

    authors: Vos SB,Tax CM,Luijten PR,Ourselin S,Leemans A,Froeling M

    更新日期:2017-01-01 00:00:00

  • In vivo MR elastography of the prostate gland using a transurethral actuator.

    abstract::Conventional approaches for MR elastography (MRE) using surface drivers have difficulty achieving sufficient shear wave propagation in the prostate gland due to attenuation. In this study we evaluate the feasibility of generating shear wave propagation in the prostate gland using a transurethral device. A novel transu...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22038

    authors: Chopra R,Arani A,Huang Y,Musquera M,Wachsmuth J,Bronskill M,Plewes D

    更新日期:2009-09-01 00:00:00

  • Direct comparison of in vivo versus postmortem second-order motion-compensated cardiac diffusion tensor imaging.

    abstract:PURPOSE:To directly compare in vivo versus postmortem second-order motion-compensated spin-echo diffusion tensor imaging of the porcine heart. METHODS:Second-order motion-compensated spin-echo cardiac diffusion tensor imaging was performed during systolic contraction in vivo and repeated upon cardiac arrest by bariumc...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26871

    authors: Stoeck CT,von Deuster C,Fleischmann T,Lipiski M,Cesarovic N,Kozerke S

    更新日期:2018-04-01 00:00:00

  • Improved sensitivity to overlapping multiplet signals in in vivo proton spectroscopy using a multiecho volume selective (CPRESS) experiment.

    abstract::A method for volume selective proton spectroscopy is presented based on a multiecho sequence with short refocusing interval tcp. It is demonstrated, that by appropriate choice of tcp on the order of 4-6 ms, signals from overlapping multiplets like the glutamine and glutamate (Glu/Gln) resonances in spectra of the huma...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910370603

    authors: Hennig J,Thiel T,Speck O

    更新日期:1997-06-01 00:00:00

  • Time-dependent effects of hormone-deprivation therapy on prostate metabolism as detected by combined magnetic resonance imaging and 3D magnetic resonance spectroscopic imaging.

    abstract::Combined MRI and 3D spectroscopic imaging (MRI/3D-MRSI) was used to study the metabolic effects of hormone-deprivation therapy in 65 prostate cancer patients, who underwent either short, intermediate, or long-term therapy, compared to 30 untreated control patients. There was a significant time-dependent loss of the pr...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1159

    authors: Mueller-Lisse UG,Swanson MG,Vigneron DB,Hricak H,Bessette A,Males RG,Wood PJ,Noworolski S,Nelson SJ,Barken I,Carroll PR,Kurhanewicz J

    更新日期:2001-07-01 00:00:00

  • Generalization of intravoxel incoherent motion model by introducing the notion of continuous pseudodiffusion variable.

    abstract:PURPOSE:A generalized intravoxel incoherent motion (IVIM) model, called the GIVIM, was proposed to better account for complex perfusion present in the tissues having various vessels and flow regimes, such as the liver. THEORY AND METHODS:The notions of continuous pseudodiffusion variable as well as perfusion fraction ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26064

    authors: Kuai ZX,Liu WY,Zhang YL,Zhu YM

    更新日期:2016-11-01 00:00:00

  • Molecular imaging of angiogenic therapy in peripheral vascular disease with alphanubeta3-integrin-targeted nanoparticles.

    abstract::Noninvasive molecular imaging of angiogenesis could play a critical role in the clinical management of peripheral vascular disease patients. The alpha(nu)beta(3)-integrin, a well-established biomarker of neovascular proliferation, is an ideal target for molecular imaging of angiogenesis. This study investigates whethe...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22447

    authors: Winter PM,Caruthers SD,Allen JS,Cai K,Williams TA,Lanza GM,Wickline SA

    更新日期:2010-08-01 00:00:00

  • Slow magic-angle coil spinning: a high-sensitivity and high-resolution NMR strategy for microscopic biological specimens.

    abstract::High-resolution magic-angle spinning has become a valuable tool to study biologic samples; however, there are only a few high-resolution magic-angle spinning methodologies that have been explored specifically to deal with small semisolid biomaterials such as tissues. Here, we report a novel high-resolution (1)H NMR sp...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22231

    authors: Wong A,Aguiar PM,Sakellariou D

    更新日期:2010-02-01 00:00:00

  • MR pulsatility measurements in peripheral arteries: preliminary results.

    abstract::Phase contrast flow velocity measurements were performed in six healthy volunteers and 30 patients with arteriosclerotic disease. The iliac arteries were investigated in 8 cases and the femoral arteries in 28 cases. In the first 24 patients, 16 evenly distributed data sets were acquired during one cardiac cycle. In th...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910340508

    authors: Krug B,Kugel H,Harnischmacher U,Heindel W,Schmidt R,Krings F

    更新日期:1995-11-01 00:00:00

  • Maximum entropy and 2DFT NMR images.

    abstract::A comparison between contrast and signal-to-noise ratio (SNR), as obtained by both maximum entropy (ME) and 2DFT reconstruction, is reported for NMR images. Our results show that in the ME elaboration the contrast and SNR are generally increased with respect to the 2DFT elaboration. The magnitude of such an increase d...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910080310

    authors: De Simone BC,De Luca F,Maraviglia B

    更新日期:1988-11-01 00:00:00

  • Improved selectivity of double quantum coherence filtering for the detection of glutathione in the human brain in vivo.

    abstract::An improved double quantum coherence (DQC) filter for the selective in vivo detection of glutathione (GSH) in the human brain at 1.5 Tesla is presented. The goal was to minimize contamination of the DQC-filtered GSH signal at 2.9 ppm with contributions arising from GABA. The modification consists of tailoring the freq...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1094

    authors: Trabesinger AH,Boesiger P

    更新日期:2001-04-01 00:00:00

  • Correction for partial volume errors in MR heart perfusion imaging.

    abstract::Myocardial MR first-pass perfusion time courses are contaminated by signals from the ventricles (spillover) as a consequence of partial volume effects and motion. An early increase in the signal intensity from the myocardium is an indicator of contamination. This contamination leads to under- or overestimation of perf...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20015

    authors: Köstler H,Ritter C,Reiss-Zimmermann M,Beer M,Hahn D,Sandstede J

    更新日期:2004-04-01 00:00:00

  • An automated iterative algorithm for the quantitative analysis of in vivo spectra based on the simplex optimization method.

    abstract::The success in utilizing in vivo NMR to identify and/or monitor metabolic abnormalities will be determined in large part on the reliability with which the spectral parameters of the metabolites present can be measured. For these reasons it is clear that there is a need for the development of algorithms with which to o...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910100306

    authors: Lenkinski RE,Allman T,Scheiner JD,Deming SN

    更新日期:1989-06-01 00:00:00

  • Determination of regional brain temperature using proton magnetic resonance spectroscopy to assess brain-body temperature differences in healthy human subjects.

    abstract::Proton magnetic resonance spectroscopy ((1)H MRS) was used to determine brain temperature in healthy volunteers. Partially water-suppressed (1)H MRS data sets were acquired at 3T from four different gray matter (GM)/white matter (WM) volumes. Brain temperatures were determined from the chemical-shift difference betwee...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21100

    authors: Childs C,Hiltunen Y,Vidyasagar R,Kauppinen RA

    更新日期:2007-01-01 00:00:00

  • Localized 7Li MR spectroscopy and spin relaxation in rat brain in vivo.

    abstract::Localized 7Li MR point-resolved spectroscopy (PRESS) was developed as a technique to measure lithium (Li) concentration in rat brain in vivo. Localized 7Li spectra could be obtained at 4.7 T in a 0.7-ml voxel in rat brain over the entire therapeutic range of serum Li for humans. Localized 7Li spin-lattice (T1) and spi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20112

    authors: Komoroski RA,Pearce JM

    更新日期:2004-07-01 00:00:00

  • Transmit SENSE.

    abstract::The idea of using parallel imaging to shorten the acquisition time by the simultaneous use of multiple receive coils can be adapted for the parallel transmission of a spatially-selective multidimensional RF pulse. As in data acquisition, a multidimensional RF pulse follows a certain k-space trajectory. Shortening this...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10353

    authors: Katscher U,Börnert P,Leussler C,van den Brink JS

    更新日期:2003-01-01 00:00:00

  • Fast 3D ultrashort echo-time spiral projection imaging using golden-angle: A flexible protocol for in vivo mouse imaging at high magnetic field.

    abstract:PURPOSE:To develop a fast three-dimensional (3D) k-space encoding method based on spiral projection imaging (SPI) with an interleaved golden-angle approach and to validate this novel sequence on small animal models. METHODS:A disk-like trajectory, in which each disk contained spirals, was developed. The 3D encoding wa...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26263

    authors: Castets CR,Lefrançois W,Wecker D,Ribot EJ,Trotier AJ,Thiaudière E,Franconi JM,Miraux S

    更新日期:2017-05-01 00:00:00

  • Saturated double-angle method for rapid B1+ mapping.

    abstract::For in vivo magnetic resonance imaging at high field (> or =3 T) it is essential to consider the homogeneity of the active B(1) field (B(1)+), particularly if surface coils are used for RF transmission. A new method is presented for highly rapid B(1)+ magnitude mapping. It combines the double angle method with a B(1)-...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20896

    authors: Cunningham CH,Pauly JM,Nayak KS

    更新日期:2006-06-01 00:00:00

  • Evaluation of acute brain edema using quantitative magnetic resonance imaging: effects of pretreatment with dexamethasone.

    abstract::We developed a quantitative magnetic resonance imaging method to permit a rapid assessment of brain water content during osmotic brain edema produced by intraperitoneal (ip) injection of distilled water. Fifteen minutes after water injection, the normalized mean image intensity (MIn) from a spin-echo pulse sequence (T...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910240107

    authors: Olson JE,Katz-Stein A,Reo NV,Jolesz FA

    更新日期:1992-03-01 00:00:00

  • In vivo measurement of T2 distributions and water contents in normal human brain.

    abstract::Using a 32-echo imaging pulse sequence, T2 relaxation decay curves were acquired from five white- and six gray-matter brain structures outlined in 12 normal volunteers. The water contents of white and gray matter were 0.71 (0.01) and 0.83 (0.03) g/ml, respectively. All white-matter structures had significantly higher ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910370107

    authors: Whittall KP,MacKay AL,Graeb DA,Nugent RA,Li DK,Paty DW

    更新日期:1997-01-01 00:00:00

  • Iterative projection onto convex sets for quantitative susceptibility mapping.

    abstract:PURPOSE:Quantitative susceptibility map (QSM) reconstruction is ill posed due to the zero values on the "magic angle cone" that make the maps prone to streaking artifacts. We propose projection onto convex sets (POCS) in the method of steepest descent (SD) for QSM reconstruction. METHODS:Two convex projections, an obj...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25155

    authors: Deng W,Boada F,Poser BA,Schirda C,Stenger VA

    更新日期:2015-02-01 00:00:00

  • Multispectral imaging with three-dimensional rosette trajectories.

    abstract::Two-dimensional intersecting k-space trajectories have previously been demonstrated to allow fast multispectral imaging. Repeated sampling of k-space points leads to destructive interference of the signal coming from the off-resonance spectral peaks; on-resonance data reconstruction yields images of the on-resonance p...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21551

    authors: Bucholz EK,Song J,Johnson GA,Hancu I

    更新日期:2008-03-01 00:00:00

  • Safety of gadolinium-DTPA: extended clinical experience.

    abstract::This review reports data on the general and renal tolerance of the paramagnetic contrast agent Gd-DTPA after intravenous administration. Gd-DTPA was administered usually at a dose level of 0.1-0.2 mmol/kg body wt (range: 0.005-0.25 mmol/kg body wt) in cranial, spinal and body MR indications. In phase I-IIIa studies a ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章,评审

    doi:10.1002/mrm.1910220212

    authors: Niendorf HP,Haustein J,Cornelius I,Alhassan A,Clauss W

    更新日期:1991-12-01 00:00:00