Slow magic-angle coil spinning: a high-sensitivity and high-resolution NMR strategy for microscopic biological specimens.

Abstract:

:High-resolution magic-angle spinning has become a valuable tool to study biologic samples; however, there are only a few high-resolution magic-angle spinning methodologies that have been explored specifically to deal with small semisolid biomaterials such as tissues. Here, we report a novel high-resolution (1)H NMR spectroscopic approach using magic-angle coil spinning. We demonstrate its potential for intact tissues by combining a resonant microcoil with a large-volume commercial magic-angle spinning rotor, where the microcoil offers incredible sensitivity and the large-volume magic-angle spinning rotor provides stable slow magic-angle spinning. This approach provides high-resolution spectra with high sensitivity and the preservation of living biologic specimens for an accurate chemical analysis.

journal_name

Magn Reson Med

authors

Wong A,Aguiar PM,Sakellariou D

doi

10.1002/mrm.22231

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

269-74

issue

2

eissn

0740-3194

issn

1522-2594

journal_volume

63

pub_type

杂志文章
  • High-resolution 1 H-MRSI of the brain using short-TE SPICE.

    abstract:PURPOSE:To improve signal-to-noise ratio (SNR) for high-resolution spectroscopic imaging using a subspace-based technique known as SPectroscopic Imaging by exploiting spatiospectral CorrElation (SPICE). METHODS:The proposed method is based on a union-of-subspaces model of MRSI signals, which exploits the partial separ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26130

    authors: Ma C,Lam F,Ning Q,Johnson CL,Liang ZP

    更新日期:2017-02-01 00:00:00

  • Voxelwise analysis of simultaneously acquired and spatially correlated 18 F-fluorodeoxyglucose (FDG)-PET and intravoxel incoherent motion metrics in breast cancer.

    abstract:PURPOSE:Diffusion-weighted imaging (DWI) and 18 F-fluorodeoxyglucose-positron emission tomography (18 F-FDG-PET) independently correlate with malignancy in breast cancer, but the relationship between their structural and metabolic metrics is not completely understood. This study spatially correlates diffusion, perfusio...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26505

    authors: Ostenson J,Pujara AC,Mikheev A,Moy L,Kim SG,Melsaether AN,Jhaveri K,Adams S,Faul D,Glielmi C,Geppert C,Feiweier T,Jackson K,Cho GY,Boada FE,Sigmund EE

    更新日期:2017-09-01 00:00:00

  • Online correction of respiratory-induced field disturbances for continuous MR-thermometry in the breast.

    abstract::MR-thermometry allows monitoring of the local temperature evolution during minimally invasive interventional therapies. However, for the particular case of MR-thermometry in the human breast, magnetic field variations induced by the respiratory cycle lead to phase fluctuations requiring a suitable correction strategy ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21954

    authors: Hey S,Maclair G,de Senneville BD,Lepetit-Coiffe M,Berber Y,Köhler MO,Quesson B,Moonen CT,Ries M

    更新日期:2009-06-01 00:00:00

  • Cardiac tagging with breath-hold cine MRI.

    abstract::A method is presented for measuring myocardial deformation in a breath-hold with tagged cine MRI. Tagged cine images of human hearts are obtained in arbitrary oblique planes on a standard imager with as few as four heartbeats. The scan time has been reduced 16- to 64-fold from previous techniques. ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910280214

    authors: McVeigh ER,Atalar E

    更新日期:1992-12-01 00:00:00

  • Cellular imaging and texture analysis distinguish differences in cellular dynamics in mouse brain tumors.

    abstract:PURPOSE:The heterogeneous tumor cell population and dynamic microenvironment within a tumor lead to regional variations in cell proliferation, migration, and differentiation. In this work, MRI and optical projection tomography were used to examine and compare the redistribution of a cellular label in two mouse glioma m...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24790

    authors: Gazdzinski LM,Nieman BJ

    更新日期:2014-04-01 00:00:00

  • Field camera measurements of gradient and shim impulse responses using frequency sweeps.

    abstract:PURPOSE:Applications of dynamic shimming require high field fidelity, and characterizing the shim field dynamics is therefore necessary. Modeling the system as linear and time-invariant, the purpose of this work was to measure the impulse response function with optimal sensitivity. THEORY AND METHODS:Frequency-swept p...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24934

    authors: Vannesjo SJ,Dietrich BE,Pavan M,Brunner DO,Wilm BJ,Barmet C,Pruessmann KP

    更新日期:2014-08-01 00:00:00

  • Toward direct mapping of neuronal activity: MRI detection of ultraweak, transient magnetic field changes.

    abstract::A novel method based on selective detection of rapidly changing DeltaB(0) magnetic fields and suppression of slowly changing DeltaB(0) fields is presented. The ultimate goal of this work is to present a method that may allow detection of transient and subtle changes in B(0) in cortical tissue associated with electrica...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10159

    authors: Bodurka J,Bandettini PA

    更新日期:2002-06-01 00:00:00

  • Editing through multiple bonds: threonine detection.

    abstract::In in vivo (1)H spectroscopy, the signal at 1.32 ppm is usually assigned to lactate. This resonance position is shared with threonine at physiological pH. The similarity of spectral patterns of lactate and threonine renders the separate measurement of either threonine or lactate without and even with editing technical...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21492

    authors: Marjanska M,Henry PG,Uğurbil K,Gruetter R

    更新日期:2008-02-01 00:00:00

  • Transrectal probe for 1H MRI and 31P MR spectroscopy of the prostate gland.

    abstract::A transrectal probe for 1H imaging and 31P MR spectroscopy of the prostate gland is described. The probe is covered with plastic and consists of an insectional portion containing an rf coil and a handle containing a tuning and matching circuit. Using this transrectal probe, 1H MR images and the first 31P MR spectra of...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章,评审

    doi:10.1002/mrm.1910110209

    authors: Narayan P,Vigneron DB,Jajodia P,Anderson CM,Hedgcock MW,Tanagho EA,James TL

    更新日期:1989-08-01 00:00:00

  • On multiple alternating steady states induced by periodic spin phase perturbation waveforms.

    abstract::Direct measurement of neural currents by means of MRI can potentially open a high temporal resolution (10-100 ms) window applicable for monitoring dynamics of neuronal activity without loss of the high spatial resolution afforded by MRI. Previously, we have shown that the alternating balanced steady state imaging affo...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23105

    authors: Buračas GT,Jung Y,Lee J,Buxton RB,Wong EC,Liu TT

    更新日期:2012-05-01 00:00:00

  • Optimization and validation of accelerated golden-angle radial sparse MRI reconstruction with self-calibrating GRAPPA operator gridding.

    abstract:PURPOSE:Golden-angle radial sparse parallel (GRASP) MRI reconstruction requires gridding and regridding to transform data between radial and Cartesian k-space. These operations are repeatedly performed in each iteration, which makes the reconstruction computationally demanding. This work aimed to accelerate GRASP recon...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27030

    authors: Benkert T,Tian Y,Huang C,DiBella EVR,Chandarana H,Feng L

    更新日期:2018-07-01 00:00:00

  • System identification theory in pharmacokinetic modeling of dynamic contrast-enhanced MRI: influence of contrast injection.

    abstract::Optimization of experimental settings of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), like the contrast administration protocol, is of great importance for reliable quantification of the microcirculatory properties, such as the volume transfer-constant K(trans). Using system identification theory an...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21575

    authors: Aerts HJ,van Riel NA,Backes WH

    更新日期:2008-05-01 00:00:00

  • On the application of ultra-fast RARE experiments.

    abstract::The ultra-fast application of the RARE experiment is described in detail, with special emphasis on its multifarious applications with preparation experiments that produce transverse magnetization. The factors affecting the temporal evolution of the magnetization during the experiment are described, and the implication...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910270114

    authors: Norris DG,Börnert P,Reese T,Leibfritz D

    更新日期:1992-09-01 00:00:00

  • Reduction of B1 sensitivity in selective single-slab 3D turbo spin echo imaging with very long echo trains.

    abstract::Single-slab 3D turbo/fast spin echo (SE) imaging with very long echo trains was recently introduced with slab selection using a highly selective excitation pulse and short, nonselective refocusing pulses with variable flip angles for high imaging efficiency. This technique, however, is vulnerable to image degradation ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22070

    authors: Park J,Mugler JP 3rd,Hughes T

    更新日期:2009-10-01 00:00:00

  • A semiautomatic method for rapid segmentation of velocity-encoded myocardial magnetic resonance imaging data.

    abstract:PURPOSE:To develop a semiautomatic method for rapid segmentation of myocardial tissue phase mapping (TPM) data. METHODS:Manual segmentation of the myocardium was performed at end-diastole and end-systole. The points in both user-defined masks were then automatically tracked over the entire cardiac cycle using temporal...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26486

    authors: Espe EKS,Skårdal K,Aronsen JM,Zhang L,Sjaastad I

    更新日期:2017-09-01 00:00:00

  • SAR comparison between CASL and pCASL at high magnetic field and evaluation of the benefit of a dedicated labeling coil.

    abstract:PURPOSE:To investigate the heating induced by (pseudo)-continuous arterial spin labeling ((p)CASL) sequences in vivo at 9.4T and to evaluate the benefit of a dedicated labeling coil. METHODS:Temperature was measured continuously in the brain, neck, and rectum of 9 rats with fiber-optic temperature probes while running...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27931

    authors: Hirschler L,Collomb N,Voiron J,Köhler S,Barbier EL,Warnking JM

    更新日期:2020-01-01 00:00:00

  • MRI reconstruction using deep Bayesian estimation.

    abstract:PURPOSE:To develop a deep learning-based Bayesian estimation for MRI reconstruction. METHODS:We modeled the MRI reconstruction problem with Bayes's theorem, following the recently proposed PixelCNN++ method. The image reconstruction from incomplete k-space measurement was obtained by maximizing the posterior possibili...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28274

    authors: Luo G,Zhao N,Jiang W,Hui ES,Cao P

    更新日期:2020-10-01 00:00:00

  • Chemically induced analgesic nephropathy in the rat monitored by proton-electron double-resonance imaging (PEDRI).

    abstract::Proton-electron double-resonance imaging (PEDRI) was used to assess renal function by monitoring the flow of the exogenous nitroxide free radical proxyl carboxylic acid (PCA) through normal and injured kidneys in the living rat. Kidney damage was induced by treatment with 2-bromoethylamine (BEA), which provides a well...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910400214

    authors: Seimenis I,Foster MA,Lurie DJ,Hutchison JM,Whiting PH,Payne S

    更新日期:1998-08-01 00:00:00

  • Sensitivity of feedback-enhanced MRI contrast to macroscopic and microscopic field variations.

    abstract::Nonlinear feedback interactions have been shown to amplify contrast due to small differences in resonance frequency arising from microscopic susceptibility variations. Determining whether the selectivity of feedback-based contrast enhancement for small resonance frequency variations remains valid even in the presence ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21584

    authors: Huang SY,Yang SS,Lin YY

    更新日期:2009-04-01 00:00:00

  • Piezoelectric-controlled tuning capacitor for surface coils.

    abstract::The design of a piezoelectric-controlled trimmer capacitor and its use as a tuning element of an MRI surface coil at 63.8 MHz are described. It is found that image quality does not depend strongly on match of the coil to the transmission line but that tuning can be a significant factor. The work is intended to lead ev...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910120106

    authors: Hyde JS,Rilling RJ,Jesmanowicz A,Kneeland JB

    更新日期:1989-10-01 00:00:00

  • Improved estimation of velocity and flow rate using regularized three-point phase-contrast velocimetry.

    abstract::We improved the three-point phase-contrast method by regularization of MR velocity data after acquisition of a low velocity-to-noise ratio (VNR) velocity image and a high VNR aliased velocity image. The phase unwrapping algorithm is based on the assumed correlation of the velocity of adjacent flow voxels on the low VN...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/1522-2594(200007)44:1<122::aid-mrm18>3.0.c

    authors: Herment A,Mousseaux E,Jolivet O,DeCesare A,Frouin F,Todd-Pokropek A,Bittoun J

    更新日期:2000-07-01 00:00:00

  • Restricted field of view magnetic resonance imaging of a dynamic time series.

    abstract::A restricted field of view (rFOV) approach for imaging a dynamic time series of volumes of limited spatial extent within a larger subject is described. The shorter readout with rFOV-MRI can be exploited to either limit image artifacts or increase spatial resolution. To accomplish rFOV imaging of a multislice volume fo...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21115

    authors: Pisani L,Bammer R,Glover G

    更新日期:2007-02-01 00:00:00

  • Quantitative measurement of regional lung ventilation using 3He MRI.

    abstract::A new strategy for a quantitative measurement of regional pulmonary ventilation using hyperpolarized helium-3 (3He) MRI has been developed. The method employs the build-up of the signal intensity after a variable number of (3)He breaths. A mathematical model of the signal dynamics is presented, from which the local ve...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10206

    authors: Deninger AJ,Månsson S,Petersson JS,Pettersson G,Magnusson P,Svensson J,Fridlund B,Hansson G,Erjefeldt I,Wollmer P,Golman K

    更新日期:2002-08-01 00:00:00

  • Contrast-enhanced MRI of brown adipose tissue after pharmacological stimulation.

    abstract::A non-invasive method for studying the modifications induced in lipid depots by hormonal stimulation could extend knowledge of adipose tissues. We studied the effect of adrenergic stimulation on interscapular brown adipose tissue (IBAT) of rats using contrast-enhanced MRI. Controls and rats pre-treated with adrenaline...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20851

    authors: Sbarbati A,Cavallini I,Marzola P,Nicolato E,Osculati F

    更新日期:2006-04-01 00:00:00

  • Sodium imaging of human brain at 7 T with 15-channel array coil.

    abstract::Signal-to-noise ratio (SNR) is a major challenge to sodium magnetic resonance imaging. Phased array coils have been shown significantly improving SNR in proton imaging over volume coils. This study investigates SNR advantage of a 15-channel array head coil (birdcage volume coil for transmit/receive and 15-channel arra...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24192

    authors: Qian Y,Zhao T,Wiggins GC,Wald LL,Zheng H,Weimer J,Boada FE

    更新日期:2012-12-01 00:00:00

  • Clinically compatible MRI strategies for discriminating bound and pore water in cortical bone.

    abstract::Advances in modern magnetic resonance imaging (MRI) pulse sequences have enabled clinically practical cortical bone imaging. Human cortical bone is known to contain a distribution of T(1) and T(2) components attributed to bound and pore water, although clinical imaging approaches have yet to discriminate bound from po...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24186

    authors: Horch RA,Gochberg DF,Nyman JS,Does MD

    更新日期:2012-12-01 00:00:00

  • Global and peak local specific absorption rate control on parallel transmit systems using k-means SAR compression model.

    abstract:PURPOSE:To improve the specific absorption rate (SAR) compression model capability in parallel transmission (pTx) MRI systems. METHODS:A k-means clustering method is proposed to group voxels with similar SAR behaviors in the scanned object, providing a controlled upper-bounded estimation of peak local SARs. This k-mea...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28456

    authors: Mao X,Bari S,Love DJ,Rispoli JV

    更新日期:2021-02-01 00:00:00

  • Robust motion correction in CEST imaging exploiting low-rank approximation of the z-spectrum.

    abstract:PURPOSE:To introduce and evaluate an image registration technique for robust quantification of CEST acquisitions corrupted by motion. METHODS:The proposed iterative algorithm exploits a low-rank approximation of the z-spectrum (LRAZ), to gradually separate the contrast variation due to saturation at different off-reso...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27206

    authors: Wech T,Köstler H

    更新日期:2018-11-01 00:00:00

  • A strictly noninvasive MR setup dedicated to longitudinal studies of mechanical performance, bioenergetics, anatomy, and muscle recruitment in contracting mouse skeletal muscle.

    abstract::MR techniques have proven their ability to investigate skeletal muscle function in situ. Their benefit in terms of noninvasiveness is, however, lost in animal research, given that muscle stimulation and force output measurements are usually achieved using invasive surgical procedures, thereby excluding repeated invest...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22386

    authors: Giannesini B,Vilmen C,Le Fur Y,Dalmasso C,Cozzone PJ,Bendahan D

    更新日期:2010-07-01 00:00:00

  • The analytic theory, optimization, and performance of transparent pulses.

    abstract::Transparent pulses are defined by the property of having no net effect on stationary spins, while selectively nutating and dephasing flowing spins. They are derived from the inverse scattering transform, a nonlinear extension of the inverse Fourier transform. They can be used as presaturation pulses to suppress select...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910240212

    authors: Buonocore MH

    更新日期:1992-04-01 00:00:00