Molecular imaging of angiogenic therapy in peripheral vascular disease with alphanubeta3-integrin-targeted nanoparticles.

abstract：:The commercial synthetic homopolypeptide polyaspartate (average MW = 30,000, approximately 220 monomers) in solution quantitatively binds up to 40 mol Gd3+ ions per mole of polyaspartate. The water proton relaxivity of the solutions is far higher than that of clinically used or commonly investigated gadolinium(III) co...

journal_title：Magnetic resonance in medicine

authors： Cavagna F,Luchinat C,Scozzafava A,Xia Z

更新日期：1994-01-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) was conducted to observe the effects of cocaine administration on the physiological fluctuations of fMRI signal in two brain regions. Seven long-term cocaine users with an average age of 32 years and 8 years of cocaine use history were recruited for the study. A T2*-weighte...

journal_title：Magnetic resonance in medicine

authors： Li SJ,Biswal B,Li Z,Risinger R,Rainey C,Cho JK,Salmeron BJ,Stein EA

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:Recently, natural d-glucose was suggested as a potential biodegradable contrast agent. The feasibility of using d-glucose for dynamic perfusion imaging was explored to detect malignant brain tumors based on blood brain barrier breakdown. METHODS:Mice were inoculated orthotopically with human U87-EGFRvIII gliom...

journal_title：Magnetic resonance in medicine

authors： Xu X,Chan KW,Knutsson L,Artemov D,Xu J,Liu G,Kato Y,Lal B,Laterra J,McMahon MT,van Zijl PC

更新日期：2015-12-01 00:00:00

abstract：:Perfusion imaging by arterial spin labeling (ASL) can be highly sensitive to the transit time from the labeling site to the tissue. We report the results of a study designed to separate the transit time and perfusion contributions to activation in ASL images accompanying motor and visual stimulation. Fractional transi...

journal_title：Magnetic resonance in medicine

authors： Gonzalez-At JB,Alsop DC,Detre JA

更新日期：2000-05-01 00:00:00

abstract：:Genetically engineered mouse models provide enormous potential for investigation of the underlying mechanisms of atherosclerotic disease, but noninvasive imaging methods for analysis of atherosclerosis in mice are currently limited. This study aimed to demonstrate the feasibility of MRI to noninvasively visualize athe...

journal_title：Magnetic resonance in medicine

authors： Wiesmann F,Szimtenings M,Frydrychowicz A,Illinger R,Hunecke A,Rommel E,Neubauer S,Haase A

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:Quantitative susceptibility mapping can be performed through the minimization of a function consisting of data fidelity and regularization terms. For data consistency, a Gaussian-phase noise distribution is often assumed, which breaks down when the signal-to-noise ratio is low. A previously proposed alternative...

journal_title：Magnetic resonance in medicine

authors： Milovic C,Bilgic B,Zhao B,Acosta-Cabronero J,Tejos C

更新日期：2018-08-01 00:00:00

abstract：:Two different types of (co-registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel-by-pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial (18)FDG PET and (1)H(2)O MR images of the human brai...

journal_title：Magnetic resonance in medicine

authors： Sammi MK,Felder CA,Fowler JS,Lee JH,Levy AV,Li X,Logan J,Pályka I,Rooney WD,Volkow ND,Wang GJ,Springer CS Jr

更新日期：1999-08-01 00:00:00

abstract：:A robust postprocessing method to detect regions of magnetic field change is presented. High resolution gradient echo data is acquired to create a complex baseline image. From this image, two low resolution images are obtained by applying a low pass filter on the magnitude image and the complex image, respectively. Su...

journal_title：Magnetic resonance in medicine

authors： Lai S,Reichenbach JR,Haacke EM

更新日期：1996-11-01 00:00:00

abstract：:Simulations of dynamic susceptibility contrast (DSC) MRI are frequently performed by assuming a certain shape for the input function and the microvascular response function. However, to investigate the influence of parameters that will affect the shape of the input function, a more complex model of the human vasculatu...

journal_title：Magnetic resonance in medicine

authors： van Osch MJ,Vonken EJ,Wu O,Viergever MA,van der Grond J,Bakker CJ

更新日期：2003-09-01 00:00:00

abstract：:High-quality, high-resolution, proton-decoupled natural-abundance 13C NMR spectra have been obtained in vitro at 100.6 MHz from unprocessed human pathology specimens of tumors and adjacent nonneoplastic control tissues from lung, colon, and prostate. In these preliminary studies, specific molecular parameters were ide...

journal_title：Magnetic resonance in medicine

authors： Halliday KR,Fenoglio-Preiser C,Sillerud LO

更新日期：1988-08-01 00:00:00

abstract：PURPOSE:To develop a method to use information from multiple MRI contrasts to produce a composite angiogram with reduced sequence-specific artifacts and improved vessel depiction. METHODS:Bayesian posterior vessel probability was determined as a function of black blood (BB), contrast enhanced angiography (CE-MRA), and...

journal_title：Magnetic resonance in medicine

authors： Kim D,Edjlali M,Turski P,Johnson KM

更新日期：2020-03-01 00:00:00

abstract：:Reduction of image-to-image signal fluctuations and imaging artifacts is important for fMRI studies. The imaging artifacts caused by respiration, cardiac pulsation, and gross head motion and the suppression of these artifacts have been studied for many years. However, the artifacts caused by eye movement and their eff...

journal_title：Magnetic resonance in medicine

authors： Chen W,Zhu XH

更新日期：1997-10-01 00:00:00

abstract：PURPOSE:To significantly reduce the background phase effects, especially at the air-tissue interface, and to enhance the desirable local structures of veins in susceptibility-weighted imaging. METHODS:In the proposed reconstruction method called Magnitude of Complex Filtering, a complex-valued magnetic resonance image...

journal_title：Magnetic resonance in medicine

authors： Lee Y,Han Y,Park H

更新日期：2014-03-01 00:00:00

abstract：:Trifluoroacetate and trifluoroacetamide, when added to a suspension of human red blood cells, give rise to separate 19F NMR signals from the intra- and extracellular species. This phenomenon has recently been exploited for measuring the membrane potential of erythrocytes. However, the separation of the peaks was incor...

journal_title：Magnetic resonance in medicine

authors： Xu AS,Potts JR,Kuchel PW

更新日期：1991-03-01 00:00:00

abstract：PURPOSE:To present and validate a new method that formalizes a direct link between k-space and wavelet domains to apply separate undersampling and reconstruction for high- and low-spatial-frequency k-space data. THEORY AND METHODS:High- and low-spatial-frequency regions are defined in k-space based on the separation o...

journal_title：Magnetic resonance in medicine

authors： Sung K,Hargreaves BA

更新日期：2013-11-01 00:00:00

abstract：:Continuous arterial spin labeling (CASL) was used to obtain an index of cerebral blood flow (ICBF) in the normal mouse brain and in an orthotopic mouse model of human U87 high-grade glioma at 8.5 T. Under the assumption of a constant tissue:blood partition coefficient for water in different tissues, the mean ICBF (n =...

journal_title：Magnetic resonance in medicine

authors： Sun Y,Schmidt NO,Schmidt K,Doshi S,Rubin JB,Mulkern RV,Carroll R,Ziu M,Erkmen K,Poussaint TY,Black P,Albert M,Burstein D,Kieran MW

更新日期：2004-05-01 00:00:00

abstract：:Changes in the exchange rate of water across the blood-brain barrier, denoted k(w), may indicate blood-brain barrier dysfunction before the leakage of large-molecule contrast agents is observable. A previously proposed approach for measuring k(w) is to use diffusion-weighted arterial spin labeling to measure the vascu...

journal_title：Magnetic resonance in medicine

authors： St Lawrence KS,Owen D,Wang DJ

更新日期：2012-05-01 00:00:00

abstract：:Segmented interleaved echo planar imaging offers a fast and efficient approach to magnetic resonance angiography. Unfortunately, this technique is particularly sensitive to oblique flow in the imaging plane. In this work, a mathematical analysis of oblique flow effects for several types of k-space coverage is presente...

journal_title：Magnetic resonance in medicine

authors： Beck G,Li D,Haacke EM,Noll TG,Schad LR

更新日期：2001-04-01 00:00:00

abstract：:To understand whether the NO-dependent vasodilator L-arginine was effective upon a chronically hypertensive cerebral capillary endothelium, dynamic susceptibility contrast MRI was used to measure the relative cerebral blood volume (rCBV) changes in nonischemic spontaneously hypertensive rats (SHRs). rCBV was measured ...

journal_title：Magnetic resonance in medicine

authors： Caramia F,Yoshida T,Hamberg LM,Huang Z,Hunter G,Wanke I,Zaharchuk G,Moskowitz MA,Rosen BR

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:Phosphomono- and diesters, the major components of the choline peak in (1) H magnetic resonance spectroscopy, are associated with membrane anabolic and catabolic mechanisms. With the refocused insensitive nuclei-enhanced polarization transfer technique, these phospholipids are edited and enhanced in the (31) P ...

journal_title：Magnetic resonance in medicine

authors： Biedermann SV,Weber-Fahr W,Demirakca T,Tunc-Skarka N,Hoerst M,Henn F,Sartorius A,Ende G

更新日期：2015-04-01 00:00:00

abstract：:When deoxygenated, blood behaves as an effective susceptibility contrast agent. Changes in brain oxygenation can be monitored using gradient-echo echo-planar imaging. With this technique, difference images also demonstrate that blood oxygenation is increased during periods of recovery from respiratory challenge. ...

journal_title：Magnetic resonance in medicine

authors： Turner R,Le Bihan D,Moonen CT,Despres D,Frank J

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:Fourier decomposition (FD) is a noninvasive method for assessing ventilation and perfusion-related information in the lungs. However, the technique has a low signal-to-noise ratio (SNR) in the lung parenchyma. We present an approach to increase the SNR in both morphological and functional images. METHODS:The d...

journal_title：Magnetic resonance in medicine

authors： Corteville DM,Kjïrstad Å,Henzler T,Zöllner FG,Schad LR

更新日期：2015-05-01 00:00:00

abstract：:Orientational anisotropy of T2 and T1 relaxation times, diffusion, and magnetization transfer has been investigated for six different tissues: tendon, cartilage, kidney, muscle, white matter, and optic nerve. Relaxation anisotropy was observed for tendon and cartilage, and diffusional anisotropy was measured in kidney...

journal_title：Magnetic resonance in medicine

authors： Henkelman RM,Stanisz GJ,Kim JK,Bronskill MJ

更新日期：1994-11-01 00:00:00

abstract：:A deficit of fatty alcohol:NAD+ oxidoreductase complex (FAO) activity has been detected in patients with the Sjögren-Larsson syndrome (SLS). A moderate decrease in FAO activity has also been reported in heterozygote SLS subjects. Abnormal peaks were detected with proton magnetic resonance spectroscopy (1H-MRS) in homo...

journal_title：Magnetic resonance in medicine

authors： Kaminaga T,Mano T,Ono J,Kusuoka H,Nakamura H,Nishimura T

更新日期：2001-06-01 00:00:00

abstract：:MRI of myocardial perfusion observed with an extracellular contrast agent has proven valuable for the detection of coronary artery disease. During contrast enhancement transient dark rim artifacts are sometimes visible, complicating diagnosis and quantification. In this work a quantification of the frequency offsets c...

journal_title：Magnetic resonance in medicine

authors： Ferreira P,Gatehouse P,Bucciarelli-Ducci C,Wage R,Firmin D

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:We propose a new acquisition to minimize the per-excitation encoding duration and improve the imaging capability for short T2 * species. METHODS:In the proposed ramped hybrid encoding (RHE) technique, gradients are applied before the radiofrequency (RF) pulse as in pointwise encoding time reduction with radial...

journal_title：Magnetic resonance in medicine

authors： Jang H,Wiens CN,McMillan AB

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:Evaluate the usefulness of single-shot and of interleaved spatiotemporally encoded (SPEN) methods to perform diffusion tensor imaging (DTI) under various preclinical and clinical settings. METHODS:A formalism for analyzing SPEN DTI data is presented, tailored to account for the spatially dependent b-matrix wei...

journal_title：Magnetic resonance in medicine

authors： Solomon E,Liberman G,Nissan N,Frydman L

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:For the application of compressive sensing to parallel MRI, Poisson disk sampling (PDS) has been shown to generate superior results compared with random sampling methods. However, due to its limited flexibility to incorporate additional constraints, PDS is not readily extendible to dynamic applications. Here, w...

journal_title：Magnetic resonance in medicine

authors： Ahmad R,Xue H,Giri S,Ding Y,Craft J,Simonetti OP

更新日期：2015-11-01 00:00:00

abstract：:A number of techniques that recently have been used for fast NMR-imaging are based on a hybrid sequence of echo planar imaging (EPI) and FLASH imaging: after each NMR excitation several k-space lines are measured. The complete k-space is covered by performance of several excitations. It has been observed that there is...

journal_title：Magnetic resonance in medicine

authors： Deichmann R,Adolf H,Nöth U,Kuchenbrod E,Schwarzbauer C,Haase A

更新日期：1995-09-01 00:00:00

abstract：:The echo-planar k-space trajectory can be used as the basis for any two-dimensional selective pulse. The main application is spectral-spatial pulses, which must be based on the echo-planar trajectory. In this paper we show how echo-planar spin-echo (EPSE) pulses may be designed. ...

journal_title：Magnetic resonance in medicine

authors： Pauly J,Spielman D,Macovski A

更新日期：1993-06-01 00:00:00