Abstract:
:A method for volume selective proton spectroscopy is presented based on a multiecho sequence with short refocusing interval tcp. It is demonstrated, that by appropriate choice of tcp on the order of 4-6 ms, signals from overlapping multiplets like the glutamine and glutamate (Glu/Gln) resonances in spectra of the human brain are considerably increased compared with a conventional PRESS volume selection scheme. Thus proton spectra from J-coupled multiplet signals can be acquired with TE on the order of 20-30 ms avoiding the baseline problems arising at shorter echo times due to broad resonances. This allows to selectively acquire spectra from substances with longer T2 without the confounding effects from J-coupling occurring in conventional volume selection techniques.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Hennig J,Thiel T,Speck Odoi
10.1002/mrm.1910370603subject
Has Abstractpub_date
1997-06-01 00:00:00pages
816-20issue
6eissn
0740-3194issn
1522-2594journal_volume
37pub_type
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