Supraphysiological thermal injury in different human bladder carcinoma cell lines.

abstract：:Point cathodal stimulation of cardiac tissue was shown previously to produce both a dog-bone shaped virtual cathode transverse to the muscle fibers and two longitudinal virtual anodes. We hypothesize that virtual anodes can cause a region of delayed activation, separating two regions of early activation caused by the ...

journal_title：Annals of biomedical engineering

authors： Wu J,Roden DM,Wikswo JP Jr

更新日期：2000-11-01 00:00:00

abstract：:The bending stiffness of a phospholipid bilayer (Kc) was measured by forming thin bilayer cylinders (tethers) from giant phospholipid vesicles. Based on the balance of forces, the tether force was expected to be proportional to the square root of the membrane tension, with a constant of proportionality containing Kc. ...

journal_title：Annals of biomedical engineering

authors： Heinrich V,Waugh RE

更新日期：1996-09-01 00:00:00

abstract：:This paper presents the bispectral analysis of the ontogeny of the hippocampal EEG recorded from the dentate gyrus and CA1, the primary sites that generate theta (theta) rhythm. The hippocampal EEG was collected during the vigilance state of rapid eye movement (REM) sleep of freely moving rats at 15, 30 and 90 days of...

journal_title：Annals of biomedical engineering

authors： Ning T,Bronzino JD

更新日期：1998-07-01 00:00:00

abstract：:Arterial responses to diverse pathologies and insults likely occur via similar mechanisms. For example, many studies suggest that the natural process of aging and isolated systolic hypertension share many characteristics in arteries, including loss of functional elastin, decreased smooth muscle tone, and altered rates...

journal_title：Annals of biomedical engineering

authors： Valentín A,Humphrey JD,Holzapfel GA

更新日期：2011-07-01 00:00:00

abstract：:Step-off edges and tissue interfaces are prevalent in cartilage injury such as after intra-articular fracture and reduction, and in focal defects and surgical repair procedures such as osteochondral graft implantation. It would be useful to assess the function of injured or donor tissues near such step-off edges and t...

journal_title：Annals of biomedical engineering

authors： Bae WC,Law AW,Amiel D,Sah RL

更新日期：2004-03-01 00:00:00

abstract：:Simulations are useful to study the heart's ability to generate flow and the interaction between contractility and loading conditions. The left ventricular pressure-volume (PV) relation has been shown to be nonlinear, but it is unknown whether a linear model is accurate enough for simulations. Six models were fitted t...

journal_title：Annals of biomedical engineering

authors： Lankhaar JW,Rövekamp FA,Steendijk P,Faes TJ,Westerhof BE,Kind T,Vonk-Noordegraaf A,Westerhof N

更新日期：2009-09-01 00:00:00

abstract：:Cerebral blood flow (CBF) increases as arterial oxygen content falls with hypoxic (low PO2), anemic (low hemoglobin) and carbon monoxide (CO) (high carboxyhemoglobin) hypoxia. Despite a higher arterial PO2, CO hypoxia provokes a greater increase in CBF than hypoxic hypoxia. We analyzed published data using a compartme...

journal_title：Annals of biomedical engineering

authors： Sharan M,Popel AS,Hudak ML,Koehler RC,Traystman RJ,Jones MD Jr

更新日期：1998-01-01 00:00:00

abstract：:"Smart" drug delivery systems should be selective and effective to ensure drug administration at the right time, at the right dosage, and anywhere in the body. Among the several administration routes and delivery systems that have been proposed, one of the most effective and promising is based on microfabricated parti...

journal_title：Annals of biomedical engineering

authors： Decuzzi P,Lee S,Decuzzi M,Ferrari M

更新日期：2004-06-01 00:00:00

abstract：:Based on mathematical expressions governing the electric field, the extracellular potentials generated by a single active fiber in a restricted circular cylindrical volume conductor are evaluated. This paper examines the effect of the extent of the volume conductor, with radius b, on the extracellular potentials at di...

journal_title：Annals of biomedical engineering

authors： Trayanova N,Henriquez CS,Plonsey R

更新日期：1990-01-01 00:00:00

abstract：:The strength between the cortical screw and bone following an orthopaedic implant surgery is an important determinant for the success of osteosynthesis. An excessive axial cutting force during drilling produces microcracks in the bone surface, resulting in reduced strength between the screw and bone, resulting in loos...

journal_title：Annals of biomedical engineering

authors： Singh RP,Gupta V,Pandey PM,Mridha AR

更新日期：2021-01-01 00:00:00

abstract：:We propose a multiphysical mathematical model by fully coupling lipid deposition, monocytes/macrophages recruitment and angiogenesis to investigate the pathophysiological responses of an atherosclerotic plaque to the dynamic changes in the microenvironment. The time evolutions of cellular (endothelial cells, macrophag...

journal_title：Annals of biomedical engineering

authors： Guo M,Cai Y,He C,Li Z

更新日期：2019-02-01 00:00:00

abstract：:A two-dimensional sheet model was used to study the dynamics of reentry around a zone of functional block. The sheet is a set of parallel, continuous, and uniform cables, transversely interconnected by a brick-wall arrangement of fixed resistors. In accord with experimental observations on cardiac tissue, longitudinal...

journal_title：Annals of biomedical engineering

authors： Leon LJ,Roberge FA,Vinet A

更新日期：1994-11-01 00:00:00

abstract：:Extraction of the cardiac surfaces of interest from multi-detector computed tomographic (MDCT) data is a pre-requisite step for cardiac analysis, as well as for image guidance procedures. Most of the existing methods need manual corrections, which is time-consuming. We present a fully automatic segmentation technique ...

journal_title：Annals of biomedical engineering

authors： Antunes S,Esposito A,Palmisano A,Colantoni C,Cerutti S,Rizzo G

更新日期：2016-05-01 00:00:00

abstract：:Statistical methods are increasingly used in biomechanics for studying bone geometry, bone density distribution and function in the population. However, relating population-based bone variation to strain during activity is computationally challenging. Here, we describe a new method for calculating strain in a populati...

journal_title：Annals of biomedical engineering

authors： Ziaeipoor H,Taylor M,Martelli S

更新日期：2020-06-01 00:00:00

abstract：:This project was undertaken to establish if the integral circulation had any effects upon the mechanical behavior of bone. The influence of blood flow in the rabbit tibia on the strain induced at the bone surface when under load was assessed. Recordings were taken from three adult and three immature New Zealand White ...

journal_title：Annals of biomedical engineering

authors： McDonald F,Pitt Ford TR

更新日期：1994-03-01 00:00:00

abstract：:Understanding the complex spatiotemporal dynamics of action potential propagation in the heart during arrhythmia is exceedingly difficult. This study applies nonlinear dynamics tools to simplify this task. Using the results of a simulation of an electrical induction of reentry in a sheet of myocardium represented as a...

journal_title：Annals of biomedical engineering

authors： Larson C,Dragnev L,Trayanova N

更新日期：2003-07-01 00:00:00

abstract：:The field of tissue engineering promises to deliver biological substitutes to repair or replace tissues in the body that have been injured or diseased. The clinical demand for musculoskeletal tissues is particularly high, especially for cartilage and bone defects. Although they are generally considered biologically si...

journal_title：Annals of biomedical engineering

authors： Sharma B,Elisseeff JH

更新日期：2004-01-01 00:00:00

abstract：:The unique resource constraints, urgency, and virulence of the coronavirus disease 2019 pandemic has sparked immense innovation in the development of barrier devices to protect healthcare providers from infectious airborne particles generated by patients during airway management interventions. Of the existing devices,...

journal_title：Annals of biomedical engineering

authors： Maloney LM,Yang AH,Princi RA,Eichert AJ,Hébert DR,Kupec TV,Mertz AE,Vasyltsiv R,Vijaya Kumar TM,Walker GJ,Peralta EJ,Hoffman JL,Yin W,Page CR

更新日期：2020-10-01 00:00:00

abstract：:Magnetic nanoparticle (mNP) based thermal therapies have demonstrated relevance in the clinic, but effective application requires an understanding of both its strengths and limitations. This study explores two critical limitations for clinical use: (1) maximizing localized mNP heating, while avoiding bulk heating due ...

journal_title：Annals of biomedical engineering

authors： Etheridge ML,Bischof JC

更新日期：2013-01-01 00:00:00

abstract：:Biologically active heart valves (tissue engineered and recellularized tissue-derived heart valves) have the potential to offer enhanced function when compared to current replacement value therapies since they can possibly remodel, and grow to meet the needs of the patient, and not require chronic medication. However,...

journal_title：Annals of biomedical engineering

authors： Hildebrand DK,Wu ZJ,Mayer JE Jr,Sacks MS

更新日期：2004-08-01 00:00:00

abstract：:Optimal treatment of proximal humerus fractures remains controversial. Locking plates offer theoretical advantages but are associated with complications in the clinic. This study aimed to perform parametric design optimisation of proximal humerus plates to enhance their mechanical performance. A finite element (FE) mo...

journal_title：Annals of biomedical engineering

authors： Jabran A,Peach C,Zou Z,Ren L

更新日期：2019-02-01 00:00:00

abstract：:Previous research in cellular adhesion has focused primarily on studying isolated cells under conditions where cells do not interact with each other. However, in vivo cells form sheets where both cell-substratum and cell-cell interactions contribute to the overall adhesive behavior. Our understanding of how cell-cell ...

journal_title：Annals of biomedical engineering

authors： Peel MM,DiMilla PA

更新日期：1999-03-01 00:00:00

abstract：:The concept of body force (force per unit volume) is introduced to account for the effect of the force generated in the radial direction by the active state of the myocardium in an elastic model of the left ventricle represented as a thick-walled cylinder contracting symmetrically. Experimental evidence for the validi...

journal_title：Annals of biomedical engineering

authors： Shoucri RM

更新日期：1991-01-01 00:00:00

abstract：:We propose a novel method to reconstruct the hypothetical geometry of the healthy vasculature prior to intracranial aneurysm (IA) formation: a Frenet frame is calculated along the skeletonization of the arterial geometry; upstream and downstream boundaries of the aneurysmal segment are expressed in terms of the local ...

journal_title：Annals of biomedical engineering

authors： Chen H,Selimovic A,Thompson H,Chiarini A,Penrose J,Ventikos Y,Watton PN

更新日期：2013-07-01 00:00:00

abstract：:The appropriateness of integrated information systems to the description of integrated biological systems is discussed. An integrated information system in the physiology of the regulation of respiration is argued to be a structural mathematical model of the system and the relational data base, which it can compute. I...

journal_title：Annals of biomedical engineering

authors： Yamamoto WS

更新日期：1983-01-01 00:00:00

abstract：:We examine the low-frequency limit of hearing of the mammalian ear through the analytical modelling of the natural frequency of the tympanic membrane. The resulting equation of the natural frequency of the modelled tympanic membrane is numerically verified against previous theoretical studies, and is statistically val...

journal_title：Annals of biomedical engineering

authors： Jabaraj DJ

更新日期：2020-01-01 00:00:00

abstract：:A coculture of endothelial cells (ECs) and smooth muscle cells (SMCs), which mimics cellular interactions appearing in vivo, has been performed in studies on the relationship between atherogenesis and fluid shear stress conditions. Although healthy arteries in vivo consist of contractile phenotype SMCs, cultured cells...

journal_title：Annals of biomedical engineering

authors： Sakamoto N,Kiuchi T,Sato M

更新日期：2011-11-01 00:00:00

abstract：:The toxic or therapeutic effect of an inhaled aerosol is highly dependent upon the site and extent of deposition in the lung. A novel MRI-based method was used to quantify the spatial distribution of particles in the rat lung. Rats were exposed to 0.95 μm-diameter iron oxide particles in a controlled manner (N = 6) or...

journal_title：Annals of biomedical engineering

authors： Oakes JM,Scadeng M,Breen EC,Prisk GK,Darquenne C

更新日期：2013-05-01 00:00:00

abstract：:Phenotype transformation of vascular smooth muscle cells (VSMCs) has been reported to be directly influenced by the frequency of mechanical strain. This study explored the effects of different frequencies of mechanical strain on expression of phenotype marker h1-calponin and the possible mechanism. VSMCs were subjecte...

journal_title：Annals of biomedical engineering

authors： Qu MJ,Liu B,Qi YX,Jiang ZL

更新日期：2008-09-01 00:00:00

abstract：:A mathematical model has been developed to investigate previously obtained experimental findings relating to the activation of factor X by surface-bound tissue factor--factor VIIa (TF:VIIa) in a tubular flow reactor. In those experiments, factor X was perfused through a microcapillary tube over a range of flow (shear)...

journal_title：Annals of biomedical engineering

authors： Gir S,Slack SM,Turitto VT

更新日期：1996-05-01 00:00:00