In vivo selection of carbapenem-resistant Klebsiella pneumoniae by OmpK36 loss during meropenem treatment.

Abstract:

:We recovered a carbapenem-resistant Klebsiella pneumoniae isolate H224 under in vivo meropenem selection pressure. Insertional inactivation of a major porin gene, ompK36, by IS5 element might play a role in acquiring carbapenem resistance in this strain harboring plasmid-borne DHA-1 AmpC beta-lactamase.

authors

Song W,Suh B,Choi JY,Jeong SH,Jeon EH,Lee YK,Hong SG,Lee K

doi

10.1016/j.diagmicrobio.2009.08.010

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

447-9

issue

4

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(09)00352-6

journal_volume

65

pub_type

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