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Evaluation of a new monoclonal antibody reagent for the detection of herpes simplex virus from clinical specimens.

Abstract：

:A reformulated fluorescein isothiocyanate conjugate-labeled monoclonal antibody typing reagent for herpes simplex virus (HSV) was compared for culture confirmation and typing with a similar commercially available HSV typing stain. There was complete agreement between the two stains in the confirmation of 240 cultures for HSV-50 negative specimens and 190 positive specimens (66 type 1 and 124 type 2). The stains were equivalent in brilliance and clarity for both HSV types, with no cross-reactivity or background staining. In addition, the PathoDx stains were also mixed 1:1 with each other to form a "bivalent" stain. This mixture again identified all 190 positive cultures and 50 negative cultures with fluorescence of equal caliber to each of the individual reagents.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Johnston SL

doi

10.1016/0732-8893(93)90137-v

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

87-8

issue

1

eissn

0732-8893

issn

1879-0070

pii

0732-8893(93)90137-V

journal_volume

16

pub_type

杂志文章

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