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Insufficient diagnostic accuracy of imported serological kits for Helicobacter pylori infection in Japanese population.

Abstract：

:Although there are many reports of the high diagnostic accuracy of commercially available serologic kits for Helicobacter pylori infection in Western countries, they rarely has been investigated in oriental population. Accordingly we examined their usefulness in 492 Japanese patients with dyspeptic symptoms. Diagnostic accuracy of 4 imported serologic kits (HEL-p TEST, HM CAP, G.A.P IgG, Helico G2) was investigated using the (13)C-urea breath test as the gold standard. When intermediate results were excluded, the sensitivity, specificity and accuracy of these serologic tests ranged from 88.6% to 97.8%, 67.9% to 85.9%, and 87.9% to 91.4%, respectively, which were comparable with reported median accuracy in the Western population. However, there were many intermediate results in these tests, ranging from 5.3% to 23.0%. Their usefulness seemed to be limited in our patient population because of the large number of intermediate results.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Miwa H,Kikuchi S,Ohtaka K,Kobayashi O,Ogihara A,Hojo M,Nagahara A,Sato N

doi

10.1016/s0732-8893(99)00143-1

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

95-9

issue

2

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(99)00143-1

journal_volume

36

pub_type

临床试验,杂志文章

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