Assessing next-generation sequencing and 4 bioinformatics tools for detection of Enterovirus D68 and other respiratory viruses in clinical samples.

Abstract:

:We used 4 different bioinformatics algorithms to evaluate the application of a metagenomic shot-gun sequencing method in detection of Enterovirus D68 and other respiratory viruses in clinical specimens. Our data supported that next-generation sequencing, combined with improved bioinformatics tools, is practically feasible and useful for clinical diagnosis of viral infections.

authors

Huang W,Wang G,Lin H,Zhuge J,Nolan SM,Vail E,Dimitrova N,Fallon JT

doi

10.1016/j.diagmicrobio.2016.01.013

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

26-9

issue

1

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(16)00032-8

journal_volume

85

pub_type

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