Abstract:
:Acinetobacter baumannii has emerged as a highly problematic hospital-associated pathogen. Different mechanisms contribute to the formation of multidrug resistance in A. baumannii, including the AdeABC efflux system. Distribution of the structural and regulatory genes encoding the AdeABC efflux system among genetically diverse clinical A. baumannii strains was achieved by using PCR and pulsed-field gel electrophoresis techniques. The distribution of adeABRS genes is extremely high among our A. baumannii strains, except the adeC gene. We have observed a large proportion of strains presenting multidrug-resistance phenotype for several years. The efflux pump could be an important mechanism in these strains in resistance to antibiotics.
journal_name
Diagn Microbiol Infect Disjournal_title
Diagnostic microbiology and infectious diseaseauthors
Wieczorek P,Sacha P,Czaban S,Hauschild T,Ojdana D,Kowalczuk O,Milewski R,Poniatowski B,Nikliński J,Tryniszewska Edoi
10.1016/j.diagmicrobio.2013.06.017subject
Has Abstractpub_date
2013-10-01 00:00:00pages
106-9issue
2eissn
0732-8893issn
1879-0070pii
S0732-8893(13)00349-0journal_volume
77pub_type
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