Matrix-assisted laser desorption/ionization time-of-flight intact cell mass spectrometry to detect emerging pathogenic Candida species.

Abstract:

:Matrix-assisted laser desorption/ionization time-of-flight intact cell mass spectrometry (MALDI-TOF-ICMS) was used to differentiate pathogenic Candida species, difficult to identify by traditional methods such as growth and biochemical reactions. Results showed that species complexes like C. parapsilosis, C. orthopsilosis, and C. metapsilsosis, and very closely related species like C. glabrata and C. bracarensis, and C. albicans and C. dubliniensis could be clearly separated. MALDI-TOF-ICMS stands out as a promising tool for the rapid detection of emerging pathogens.

authors

Santos C,Lima N,Sampaio P,Pais C

doi

10.1016/j.diagmicrobio.2011.07.002

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

304-8

issue

3

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(11)00278-1

journal_volume

71

pub_type

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