In vitro activity of l-ofloxacin against norfloxacin-resistant coagulase-negative staphylococci.

Abstract:

:The in vitro activity of l-ofloxacin was determined against coagulase-negative staphylococci that were induced to norfloxacin resistance. l-Ofloxacin was the most active agent tested with an MIC90 of 4 micrograms/ml compared with greater than 128, 32, and 128 micrograms/ml for norfloxacin, ciprofloxacin, and enoxacin, respectively. Rifampin-resistant, coagulase-negative staphylococci were not cross-resistant to the quinolones tested. Among the rifampin-resistant organisms tested, l-ofloxacin was also the most active agent with an MIC90 of 0.25 micrograms/ml.

authors

Foleno B,Fu KP

doi

10.1016/0732-8893(92)90109-7

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

557-9

issue

6

eissn

0732-8893

issn

1879-0070

pii

0732-8893(92)90109-7

journal_volume

15

pub_type

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