The clinical significance of isolation of two different organisms from the urine of patients with an indwelling catheter.

Abstract:

BACKGROUND:We evaluated the clinical significance of urine cultures from patients with an indwelling urinary catheter (UC) from which 2 different pathogens were isolated. METHODS:Urine cultures from patients with a UC from which 2 different organisms were isolated were randomly divided into a control group (culture results were reported as usual) and a study group (culture results were reported as "mixed growth"). Endpoints included change in antibiotic treatment, use of broad spectrum agents, time for clinical improvement, and duration of admission. RESULTS:A total of 81 cultures met the inclusion criteria. Antibiotic treatment was changed after 72-96 h in 19 (48%) study patients and in 25 (61%) controls (NS). There was no difference regarding narrowing or broadening of antibiotic spectrum, and duration of hospitalization was similar. In each group, 15 (36%) patients died. CONCLUSION:Our findings imply that laboratory work-up of 2 pathogens from patients with an indwelling catheter may be discarded.

authors

Wiener-Well Y,Gofman I,Assous MV,Freier-Dror Y,Yinnon AM,Lachish T

doi

10.1016/j.diagmicrobio.2013.01.015

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

1-4

issue

1

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(13)00021-7

journal_volume

76

pub_type

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