Performance of the Gen-Probe amplified Mycobacterium tuberculosis direct test in a laboratory that infrequently isolates Mycobacterium tuberculosis.

Abstract:

:The performance of the Gen-Probe Mycobacterium tuberculosis direct (MTD) test was assessed in a laboratory whose specimens were derived from a population with a low prevalence (1.3%) of tuberculosis. A total of 339 specimens from 113 patients were included in the study. Nine of 10 MTD positive samples were culture positive (smear positive, n = 7; smear negative, n = 1; smear not ordered, n = 2). The 10th MTD-positive sample, which was smear and culture negative, was from a patient whose two other study specimens were smear and culture positive and who had a clinical history consistent with tuberculosis. Prior to and following resolution of discrepant results, the sensitivities and specificities of the MTD test relative to culture were 100 and 99.7% and 100 and 100%, respectively.

authors

Welch K,Brown G,Jonas V,Ferraro MJ

doi

10.1016/0732-8893(95)00065-i

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

297-9

issue

3

eissn

0732-8893

issn

1879-0070

pii

0732-8893(95)00065-I

journal_volume

22

pub_type

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