A novel OXA-10-like beta-lactamase is present in different Enterobacteriaceae.


:OXA 101, a novel OXA-10 like enzyme, was found forming part of a class 1 integron located in a conjugative plasmid in three different species of Enterobacteriaceae. This beta-lactamase is related to OXA-35 and OXA-56 and displays a narrow substrate hydrolysis profile.


Porto A,Ayala J,Gutkind G,Di Conza J




Has Abstract


2010-02-01 00:00:00














  • Group-C beta-hemolytic streptococcal bacteremia.

    abstract::Group-C beta-hemolytic streptococci (GCBHS) is an uncommon cause of bacteremia. In a 5-year period, GCBHS accounted for 0.28% of positive blood cultures and 0.35% of bacteremias documented at our hospital. The incidence of GCBHS bacteremia was 0.05 episodes per 1000 admissions. We were able to analyze clinical data of...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Berenguer J,Sampedro I,Cercenado E,Baraia J,Rodríguez-Créixems M,Bouza E

    更新日期:1992-02-01 00:00:00

  • Colistin-resistant Enterobacteriaceae infections: clinical and molecular characterization and analysis of in vitro synergy.

    abstract::We described 27 polyclonal colistin-resistant Enterobacteriaceae (MIC 4-16 μg/mL) infections (12 pneumonia, 12 urinary tract infection (UTI), two Bacteremia, and one skin/soft tissue infection) in which 74% harbored KPC. The isolates were polyclonal, 6 STs were identified and the colistin resistance was due to chromos...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: de Maio Carrillho CM,Gaudereto JJ,Martins RC,de Castro Lima VA,de Oliveira LM,Urbano MR,Perozin JS,Levin AS,Costa SF

    更新日期:2017-03-01 00:00:00

  • Antimicrobial susceptibility of Streptococcus pyogenes in Central, Eastern, and Baltic European Countries, 2005 to 2006: the cefditoren surveillance program.

    abstract::The in vitro activity of penicillin, ampicillin, cefditoren, cefotaxime, erythromycin, clarithromycin, and levofloxacin against 763 clinical isolates of Streptococcus pyogenes was determined. Clinically significant isolates collected from November 2005 to December 2006 in the Czech Republic, Slovakia, Hungary, Poland,...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Gracia M,Díaz C,Coronel P,Gimeno M,García-Rodas R,Rodríguez-Cerrato V,del Prado G,Huelves L,Ruiz V,Naves PF,Ponte MC,Granizo JJ,Soriano F

    更新日期:2009-05-01 00:00:00

  • Comparison of two oral antibiotics, roxithromycin and amoxicillin plus clavulanic acid, in lower respiratory tract infections.

    abstract::In a randomized, multicenter, open-label study, 490 ambulatory adult patients with lower respiratory tract infection (LRTI) were randomized to roxithromycin (ROX) 150 mg b.i.d. orally (n = 244) or amoxicillin plus clavulanic acid (AMX + CA) as 500 mg AMX + 125 mg CA t.i.d orally (n = 24). Clinical results were analyze...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Dautzenberg B,Scheimberg A,Brambilla C,Camus P,Godard P,Guerin JC,Lemarie E,Rezvani Y,Rosembaum M,Tuchais E

    更新日期:1992-05-01 00:00:00

  • Evaluation of rapid culture centrifugation method for adenovirus detection in stools.

    abstract::Routine laboratory testing for adenovirus (Adv) requires a procedure that is rapid and reliable, especially for samples from children and immunosuppressed patients, when diarrhea may signal the onset of severe gastrointestinal disorders. An improved culture technique for Adv isolation, using centrifugation step of 24-...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Durepaire N,Ranger-Rogez S,Denis F

    更新日期:1996-01-01 00:00:00

  • Prevalence and epidemiology of microbial pathogens causing bloodstream infections: results of the OASIS multicenter study.

    abstract::Beginning on April 2007, a prospective multicenter study was performed to investigate prevalence and epidemiology of microbial pathogens causing bloodstream infections (BSIs). Twenty microbiology laboratories participated to the survey over a 1-year period. A total of 11,638 episodes of BSI occurred in 11 202 patients...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,多中心研究


    authors: Luzzaro F,Ortisi G,Larosa M,Drago M,Brigante G,Gesu G

    更新日期:2011-04-01 00:00:00

  • Cultures of sternal wound and mediastinum taken at the end of heart surgery do not predict postsurgical mediastinitis.

    abstract::The aim of the study was to assess of the role of intraoperative cultures taken at the end of major heart surgery (MHS) in the prediction of postoperative mediastinitis (PM) in patients undergoing MHS over a 6-month period in a tertiary university hospital. Just before wound closure, a sample of the sternal border was...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Bouza E,Muñoz P,Alcalá L,Pérez MJ,Rincón C,Barrio JM,Pinto A

    更新日期:2006-12-01 00:00:00

  • Risk factors for acquisition of vancomycin-resistant enterococci among hematology-oncology patients.

    abstract::The incidence of VRE has increased dramatically and hematology-oncology patients are at high risk for acquisition of colonization and development of infection. Therefore, we performed a prospective cohort study to determine risk factors for VRE acquisition among hematology-oncology patients. Patients admitted to a sin...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Suntharam N,Lankford MG,Trick WE,Peterson LR,Noskin GA

    更新日期:2002-07-01 00:00:00

  • Methods incorporating a polymerase chain reaction and restriction fragment length polymorphism and their use as a 'gold standard' in diagnosing Old World cutaneous leishmaniasis.

    abstract::Three polymerase chain reaction (PCR) assays - kinetoplast DNA (kDNA) PCR, 7SL PCR, ITS1 PCR - were compared for their ability to detect leishmanial parasites in the skin tissue aspirates of 212 Palestinian suspect cases of cutaneous leishmaniasis (CL). The kDNA PCR was the most sensitive, detecting 156/170 (91.8%) of...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Azmi K,Nasereddin A,Ereqat S,Schnur L,Schonian G,Abdeen Z

    更新日期:2011-10-01 00:00:00

  • Pleural effusion with negative culture: a challenge for pneumococcal diagnosis in children.

    abstract:BACKGROUND:Pneumococcal parapneumonic effusion seems to be increasing in children in the postvaccine era and is frequently associated with negative culture. Due to the low yield of culture, culture-independent tools are evaluated. METHODS:Culture-negative pleural fluid specimens from 38 children with parapneumonic eff...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Perez VP,Caierão J,Fischer GB,Dias CA,d'Azevedo PA

    更新日期:2016-10-01 00:00:00

  • In vitro activity of ampicillin, amoxicillin, ampicillin-sulbactam, and amoxicillin-clavulanic acid against consecutive clinical isolates of Enterobacteriaceae.

    abstract::Ampicillin was generally twice as active as amoxicillin against 2440 consecutive isolates of Enterobacteriaceae from five medical centers. When beta-lactamase inhibitors were added to the penicillins, there was a significant increase in susceptibility. The magnitude of the increased susceptibility to ampicillin-sulbac...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Fuchs PC,Barry AL,Pfaller MA,Hardy DJ,McLaughlin JC,Gerlach EH

    更新日期:1993-08-01 00:00:00

  • Major methodology-dependent discordant susceptibility results for Bacteroides fragilis group isolates but not other anaerobes.

    abstract::Two standardized susceptibility test methods, a broth microdilution (BMD) and agar dilution (AD) method were performed on a total of 441 clinical isolates of anaerobes with ceftizoxime, cefotaxime, ceftriaxone, cefoxitin, piperacillin, and metronidazole. Against the 339 strains of the Bacteroides fragilis group BMD mi...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Aldridge KE,Schiro DD

    更新日期:1994-11-01 00:00:00

  • IncX3 plasmid harboring a non-Tn4401 genetic element (NTEKPC) in a hospital-associated clone of KPC-2-producing Klebsiella pneumoniae ST340/CG258.

    abstract::IncX-type plasmids have achieved clinical significance for their contribution in the dissemination of genes confering resistance to carbapenems (most blaKPC- and blaNDM-type genes) and polymyxins (mcr-type genes), both antibiotics considered last resort for multidrug-resistant Gram-negative infections. In this study, ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Cerdeira LT,Cunha MPV,Francisco GR,Bueno MFC,Araujo BF,Ribas RM,Gontijo-Filho PP,Knöbl T,de Oliveira Garcia D,Lincopan N

    更新日期:2017-10-01 00:00:00

  • Characteristics and outcomes of Fusobacterium nucleatum bacteremia--a 6-year experience at a tertiary care hospital in northern Taiwan.

    abstract::Fusobacterium nucleatum bacteremia is critical and not well defined. To identify the clinical characteristics and outcomes, we conducted a retrospective review of hospitalized patients from January 2004 to December 2009 at a tertiary center in northern Taiwan. Fifty-seven patients were enrolled. The mean age was 58.1 ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Yang CC,Ye JJ,Hsu PC,Chang HJ,Cheng CW,Leu HS,Chiang PC,Lee MH

    更新日期:2011-06-01 00:00:00

  • Prevalence and risk factors for carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae among patients prior to bowel surgery.

    abstract::Prophylactic antibiotics are an important measure in preventing perioperative infection, Failure to cover multidrug-resistant pathogens may place carriers at increased risk of infection. We conducted a prospective, cross-sectional study in patients prior to bowel surgery to measure the carriage prevalence of extended-...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Pfeffer I,Zemel M,Kariv Y,Mishali H,Adler A,Braun T,Klein A,Matalon MK,Klausner J,Carmeli Y,Schwaber MJ

    更新日期:2016-07-01 00:00:00

  • Rapid identification of Branhamella catarrhalis. A comparison of five rapid methods.

    abstract::Five methods for the rapid identification and differentiation of Branhamella catarrhalis from other Neisseria species in 86 respiratory specimens were compared. These tests included the 4-methylumbelliferyl butyrate (MUB), API quadFerm, B.CAT.Confirm, Gonochek II, and the Tributyrin disc. All five tests reliably and a...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Louie M,Ongsansoy EG,Forward KR

    更新日期:1990-05-01 00:00:00

  • An evaluation of a leukocyte esterase/nitrite test strip and a bioluminescence assay for detection of bacteriuria.

    abstract::A leukocyte esterase/nitrite (Chemstrip LNTM) and a bioluminescence assay (LumacTM) were evaluated for detection of bacteriuria in 1,000 urine specimens. Both devices provided high predictive negative values (95.4-97.8%); however, false-negative values at levels of bacteriuria greater than or equal to 10(4) CFU/ml wer...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Hughes JG,Snyder RJ,Washington JA 2nd

    更新日期:1985-03-01 00:00:00

  • Hepatitis C virus core antigen in the management of patients treated with new direct-acting antivirals.

    abstract::We evaluated the utility of Architect core antigen assay® Abbott Diagnostics (HCVAg) for monitoring patients with HCV infection and compared to HCV-RNA quantification (Cobas Ampliprep TaqMan-Roche Diagnostics). Samples from 262 patients were studied. Mean baseline HCV RNA and HCVAg levels were similar for responders (...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Arboledas JCA,Guerrero IP,Rodríguez MJB,Martos ET,Pérez AB,León CC,Sierra Sánchez JF,Prieto MDL,Porcuna NC,Mochón MDO,Macías J,de la Iglesia Salgado A,Granger JR,Fernández MD,Lozano IG,Ramírez ER,Rivero A,Del Carmen Loz

    更新日期:2017-09-01 00:00:00

  • Colonization and microbiology of the motile enterococci in a patient population.

    abstract::The motile enterococci with the vanC gene have intrinsic low-level resistance to vancomycin, but have not been implicated in a nosocomial outbreak. We determined the colonization rate of motile enterococci in hospitalized and nonhospitalized patients. Perianal or stool specimens were cultured in Enterococcosel broth s...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Van Horn KG,Rodney KM

    更新日期:1998-08-01 00:00:00

  • Comparison of the performance of IFA, CFA, and ELISA assays for the serodiagnosis of acute Q fever by quality assessment.

    abstract::The indirect immunofluorescence assay (IFA) is considered the reference method for diagnosing Q fever, but serology is also performed by complement fixation assay (CFA) or enzyme-linked immunosorbent assay (ELISA). However, comparability between these assays is not clear, and therefore a quality assessment was perform...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Herremans T,Hogema BM,Nabuurs M,Peeters M,Wegdam-Blans M,Schneeberger P,Nijhuis C,Notermans DW,Galama J,Horrevorts A,van Loo IH,Vlaminckx B,Zaaijer HL,Koopmans MP,Berkhout H,Socolovschi C,Raoult D,Stenos J,Nicholson W

    更新日期:2013-01-01 00:00:00

  • Pharmacokinetics of cefotaxime in healthy volunteers and patients.

    abstract::Cefotaxime is a third-generation cephalosporin that has maintained good susceptibility pattern despite its extensive use. It is available for intravenous and intramuscular administration. Its pharmacokinetic property includes a small volume of distribution with low protein binding. Cefotaxime's half-life is approximat...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Patel KB,Nicolau DP,Nightingale CH,Quintiliani R

    更新日期:1995-05-01 00:00:00

  • Optimization of LipL32 PCR assay for increased sensitivity in diagnosing leptospirosis.

    abstract::Early diagnosis of leptospirosis in humans is critical with regard to initiation of appropriate treatment; however, the gold standard serological test cannot detect antibodies until nearly a week after symptom onset. PCR has been shown to be sensitive and specific in the early phase of leptospirosis. Previously, we de...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Galloway RL,Hoffmaster AR

    更新日期:2015-07-01 00:00:00

  • Molecular diagnosis of Arcobacter and Campylobacter in diarrhoeal samples among Portuguese patients.

    abstract::The present study was conducted to investigate the prevalence and diversity of Arcobacter and Campylobacter spp. in 298 stool samples of patients with diarrhoea, collected from 22 Portuguese hospitals, between September and November 2012. Detection of Arcobacter and Campylobacter spp. was performed using molecular-bas...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,多中心研究


    authors: Ferreira S,Júlio C,Queiroz JA,Domingues FC,Oleastro M

    更新日期:2014-03-01 00:00:00

  • Evaluation of antimicrobial susceptibility for beta-lactams using the Etest method against clinical isolates from 100 medical centers in Japan (2006).

    abstract::This antimicrobial resistance surveillance study was performed in 100 medical centers. Susceptibility testing (Etest; AB BIODISK, Solna, Sweden) of 9152 strains including Escherichia coli (991 strains), Klebsiella spp. (1000 strains), Enterobacter spp. (971 strains), Citrobacter spp. (803 strains), indole-positive Pro...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Ishii Y,Tateda K,Yamaguchi K,Japan Antimicrobial Resistance Surveillance Participants Group (JARS).

    更新日期:2008-02-01 00:00:00

  • Predicting β-lactam resistance using whole genome sequencing in Klebsiella pneumoniae: the challenge of β-lactamase inhibitors.

    abstract::Although multiple antimicrobial resistance (AMR) determinants can confer the same in vitro antimicrobial susceptibility testing (AST) phenotype, their differing effect on optimal therapeutic choices is uncertain. Using a large population-based collection of clinical strains spanning a 3.5-year period, we applied WGS t...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Hujer AM,Long SW,Olsen RJ,Taracila MA,Rojas LJ,Musser JM,Bonomo RA

    更新日期:2020-11-01 00:00:00

  • Occurrence of single-point gyrA mutations among ciprofloxacin-susceptible Escherichia coli isolates causing urinary tract infections in Latin America.

    abstract::To detect if isolates susceptible to quinolones already carry mutations in the gyrA and parC genes, we selected 12 ciprofloxacin-susceptible Escherichia coli strains collected from patients with urinary tract infections in Latin America in 1998, as part of ongoing SENTRY Antimicrobial Surveillance Program. The isolate...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Gales AC,Gordon KA,Wilke WW,Pfaller MA,Jones RN

    更新日期:2000-01-01 00:00:00

  • Prevalence of beta-lactam nonsusceptible Gram-negative bacilli and use and interpretation of current susceptibility breakpoints: a survey of infectious disease physicians.

    abstract::Beta-lactam-resistant Enterobacteriaceae represent an important public health problem; however, questions exist about their prevalence and the impact of recent breakpoint changes on clinical practice. We surveyed infectious disease physicians to better understand these issues. Many reported encountering resistant Ente...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Kallen AJ,Beekmann SE,Limbago B,Lentnek AL,Polgreen PM,Patel J,Srinivasan A

    更新日期:2011-11-01 00:00:00

  • Expansion of the E138A mutation in newly diagnosed HIV-infected patients in Gran Canaria.

    abstract::Molecular epidemiology allows us to know local HIV transmission and to design strategies of prevention. We studied 25 HIV newly diagnosed patients with the E138A mutation since the year 2010. Most transmission networks involved young and promiscuous men who have sex with men. Recent infection was only documented in pa...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Chamizo F,Gilarranz R,Tosco T,Carrillo D,Holguín Á,Santana É,Pérez-Arellano JL,Hernández M,Francés A,Cárdenes MÁ,Zarzalejos JM,Pena-López MJ

    更新日期:2016-09-01 00:00:00

  • In vivo selection of carbapenem-resistant Klebsiella pneumoniae by OmpK36 loss during meropenem treatment.

    abstract::We recovered a carbapenem-resistant Klebsiella pneumoniae isolate H224 under in vivo meropenem selection pressure. Insertional inactivation of a major porin gene, ompK36, by IS5 element might play a role in acquiring carbapenem resistance in this strain harboring plasmid-borne DHA-1 AmpC beta-lactamase. ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Song W,Suh B,Choi JY,Jeong SH,Jeon EH,Lee YK,Hong SG,Lee K

    更新日期:2009-12-01 00:00:00

  • A new diagnostic problem: isolation of Escherichia coli O157:H7 strains with aberrant biochemical properties.

    abstract::Over a five-year period (1995-1999) the Microbial Diseases Laboratory received 34 strains of E. coli O157:H7 each with a single aberrant biochemical property. In addition, 27 O157 strains with negative or delayed motility were noted during the same time period. These observations suggest that there may be an increased...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Ware JM,Abbott SL,Janda JM

    更新日期:2000-11-01 00:00:00