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Detection of antibodies to Mycoplasma pneumoniae adhesion P1 in serum specimens from infected and non-infected subjects by immunoblotting.

Abstract：

:Paired serum specimens from 17 patients with Mycoplasma pneumoniae infection, as demonstrated by a rise in complement fixation (CF) antibody titer and 14 single sera, negative in the CF test, were tested for the presence of Ig A, Ig G, and Ig M antibodies to a polypeptide with a molecular weight of 170 KDa (P1) in an immunoblot assay. In acute phase sera, collected in the 1st week of the disease, frequency of occurrence of the antibodies against P1 protein did not exceed 18%. Two to three weeks later, Ig A antibodies were detectable in 82.4%, Ig M in 76.5%, and Ig G antibodies in all convalescent phase sera. No sera negative in the CF test (titer < 4) had antibodies against M. pneumoniae adhesin P1.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Rastawicki W,Räty R,Kleemola M

doi

10.1016/s0732-8893(96)00216-7

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

141-3

issue

3-4

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(96)00216-7

journal_volume

26

pub_type

杂志文章

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