Research of flow dynamics and occlusion condition in roller pump systems used for ventricular assist.

abstract：:The energy dissipated in blood or on a total artificial heart (TAH) chamber's elements directly or indirectly decreases the biological or technical safety of the TAH's work. The energetic analysis of the Polish total artificial heart (POLTAH) external work with the objective of estimating the valve and membrane roles ...

journal_title：Artificial organs

authors： Nawrat Z,Malota Z

更新日期：1998-10-01 00:00:00

abstract：:The purpose was to evaluate the cytotoxicity of two novel formulations (alpha and beta) of calcium phosphate cements. Positive control, represented by a commercial hydroxyapatite cement, and negative control were included for comparative purposes. A continuous lineage of fibroblastic cells was used, and the effect of ...

journal_title：Artificial organs

authors： Rossa C Jr,Marcantonio E Jr,Santos LA,Boschi AO,Raddi MS

更新日期：2005-02-01 00:00:00

abstract：:Microcapsules containing insulin crystals or islets of Langerhans were made by extruding a mixture of insulin crystals or islets and sodium alginate into a calcium chloride solution, and then coating it with poly-l-lysine. When these microcapsules were incubated at 37 degrees C, insulin could be detected readily in th...

journal_title：Artificial organs

authors： Leung YF,O'Shea GM,Goosen MF,Sun AM

更新日期：1983-05-01 00:00:00

abstract：:Heparin remains the predominant anticoagulant during extracorporeal membrane oxygenation (ECMO). Heparin acts by potentiating the anticoagulant effect of antithrombin (ATIII). Acquired ATIII deficiency, common in pediatric patients requiring ECMO, may result in ineffective anticoagulation with heparin. ATIII replaceme...

journal_title：Artificial organs

authors： Niebler RA,Christensen M,Berens R,Wellner H,Mikhailov T,Tweddell JS

更新日期：2011-11-01 00:00:00

abstract：:We aimed to evaluate the timing of preoperative intra-aortic balloon pump (IABP) placement and outcomes in patients undergoing off-pump coronary artery bypass grafting (OPCAB). Patients with prophylactic IABP placement before OPCAB presenting between January 1, 2010 and December 31, 2013 were included. Patients were c...

journal_title：Artificial organs

authors： Liu F,Yang F,Du Z,Miao N,Zhao Y,Xu B,Hou X

更新日期：2018-03-01 00:00:00

abstract：:Biofilms are communities of bacteria that can cause infections which are resistant to the immune system and antimicrobial treatments, posing a significant threat for patients with implantable and indwelling medical devices. The purpose of our research was to determine if utilizing specific parameters for electric curr...

journal_title：Artificial organs

authors： Haddad PA,Mah TF,Mussivand T

更新日期：2016-08-01 00:00:00

abstract：:We aimed to determine the effect of elective left heart decompression at the time of initiation of central venoarterial extracorporeal membrane oxygenation (VA ECMO) on VA ECMO duration and clinical outcomes in children in a single tertiary ECMO referral center with a large pediatric population from a national referra...

journal_title：Artificial organs

authors： Hacking DF,Best D,d'Udekem Y,Brizard CP,Konstantinov IE,Millar J,Butt W

更新日期：2015-04-01 00:00:00

abstract：:Ten dialysis patients were followed in a prospective study to determine the neurotoxicity of metabolites in the middle molecule (MM) molecular weight (mol wt) range of 500-200 daltons/molecule. In the absence of readily available direct serum measurements of MM concentrations, a theoretically calculated dialysis index...

journal_title：Artificial organs

authors： Milutinovic J,Babb AL,Eschbach JW,Follette WC,Graefe U,Strand MJ,Scribner BH

更新日期：1978-02-01 00:00:00

abstract：:To study the microvessels in bulbar conjunctiva, we conducted an experiment in goat with a pneumatically driven left heart bypass pump, which was replaced with an undulation pump-left ventricle assist device for 9 days. Three flow patterns were tested: complete pulsatile, continuous, and percentage of pulsatile. We st...

journal_title：Artificial organs

authors： Dobsák P,Novakova M,Baba A,Vasku J,Isoyama T,Saito I,Abe Y,Chinzei T,Imachi K

更新日期：2006-06-01 00:00:00

abstract：:The use of Berlin Heart EXCOR VAD (BH) is a validated therapy to bridge pediatric patients to heart transplant. Serial echocardiographic (ECHO) assessment of VAD patients is necessary to support patients' management. This work aims at developing an innovative strategy to evaluate the BH device functioning by ECHO and ...

journal_title：Artificial organs

authors： Di Molfetta A,Iacobelli R,Ferrari G,Filippelli S,Perri G,Toscano A,Adorisio R,Guccione P,Amodeo A

更新日期：2018-04-01 00:00:00

abstract：:Medial opening-wedge has gained popularity in comparison to other techniques of high tibial osteotomy. This technique involves the creation of a gap in the tibia. Filling the gap with autologous iliac bone graft was recommended in the classic description, to prevent complications such as correction loss or delayed bon...

journal_title：Artificial organs

authors： Zorzi AR,da Silva HG,Muszkat C,Marques LC,Cliquet A Jr,de Miranda JB

更新日期：2011-03-01 00:00:00

abstract：:Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to...

journal_title：Artificial organs

authors： Mårtensson L,Nilsson R,Sjögren HO,Strand SE,Tennvall J

更新日期：2007-04-01 00:00:00

abstract：:This study explores a quantitative evaluation of blood damage that occurs in a continuous flow left ventricular assist device due to fluid stress. Computational fluid dynamics (CFD) analysis is used to track the shear stress history of 388 particle streaklines. The accumulation of shear and exposure time is integrated...

journal_title：Artificial organs

authors： Song X,Throckmorton AL,Wood HG,Antaki JF,Olsen DB

更新日期：2003-10-01 00:00:00

abstract：:Although current continuous-flow total artificial hearts (CFTAHs) are much smaller than previous models, venous kinking may still occur after device implantation, especially in smaller animals. By inserting a self-expanding stent at the site of venous narrowing in a sheep model implanted with a CFTAH, we were able to ...

journal_title：Artificial organs

authors： Tuzun E,Parnis S,Rios J,Winkler JA,Cohn WE

更新日期：2011-07-01 00:00:00

abstract：:With the goal of investigating artificial proprioception elicited by electrical stimulation, we have developed a tactile phi phenomenon-based stimulator. This two-channel microprocessed pulse amplitude modulation system generates two different envelope waveforms (triangular and elliptical) and allows programming and v...

journal_title：Artificial organs

authors： Nohama P,Lopes AV,Cliquet Júnior A

更新日期：1995-03-01 00:00:00

abstract：:Recently, there has been an increase in the use of rat models of cardiopulmonary bypass (CPB) for research purposes. Much of this work has focused on cerebral injury associated with CPB. Many of these studies employ a peripheral cannulation approach, often utilizing the caudal artery and internal or external jugular v...

journal_title：Artificial organs

authors： Gourlay T,Modine T

更新日期：2010-06-01 00:00:00

abstract：:Patients with end-stage renal failure and peripheral vascular disease pose a difficult management problem in establishing long-term angioaccess for hemodialysis. In 4 patients with access problems, we created axillary artery to contralateral axillary vein Goretex grafts. The grafts were cannulated regularly for period...

journal_title：Artificial organs

authors： Ono K,Muto Y,Yano K,Yukizane T

更新日期：1995-12-01 00:00:00

abstract：:Effect of hemodialysis (HD) on some indices of immune response was studied in nine chronic uremics. Total lymphocyte, OKT4+, and OKT8+ cell numbers significantly decreased during the first 20 min of HD, and they were decreased till the third hour of the procedure, whereas the OKT4+/OKT8+ cell number ratio did not chan...

journal_title：Artificial organs

authors： Tchórzewski H,Luciak M,Trznadel K,Majewska E,Pokoca L

更新日期：1989-06-01 00:00:00

abstract：:Midsize molecule retention is related with renal-failure-associated mortality. Here, the authors describe a new dialysis modality, pulse push/pull hemodialysis (PPPHD), which increases convective clearance. Blood and dialysate are circulated by a pulsatile pump, but with pulsatile flow patterns that are 180 degrees ou...

journal_title：Artificial organs

authors： Lee K,Lee SR,Mun CH,Min BG

更新日期：2008-05-01 00:00:00

abstract：:Testing failed to detect free isocyanates in dialyzer rinses or significant levels of immunoglobulin E antibodies to isocyanate-protein conjugates in the serum of individuals reacting during hemodialysis with dialyzers containing Cuprophan membranes. Extended immunization of rabbits with Limulus lysate-reactive materi...

journal_title：Artificial organs

authors： Butcher BT,Reed MA,O'Neil CE,Leech S,Pearson FC

更新日期：1984-08-01 00:00:00

abstract：:Over a 4 year period, five of 98 patients at our dialysis unit developed signs and symptoms consistent with first-use syndrome (FUS). Marked improvement was noted after subjecting new dialyzers to automated processing using either formaldehyde or peracetic acid. No episodes of FUS occurred in patients being treated wi...

journal_title：Artificial organs

authors： Vanholder R,Ringoir S

更新日期：1987-04-01 00:00:00

abstract：:The characteristic depressed hemodynamic state and gradually declining circulatory function in Fontan patients necessitates alternative postoperative management strategies incorporating a system level approach. In this study, the single-ventricle Fontan circulation is modeled by constructing a practical in vitro bench...

journal_title：Artificial organs

authors： Dur O,Lara M,Arnold D,Vandenberghe S,Keller BB,DeGroff C,Pekkan K

更新日期：2009-11-01 00:00:00

abstract：:The cochlea is an end organ, which is metabolically dependent on a nutrient and oxygen supply to maintain its normal physiological function. Cochlear ischemia and reperfusion (IR) injury is considered one of the most important causes of human idiopathic sudden sensorineural hearing loss. The aim of the present study w...

journal_title：Artificial organs

authors： Onal M,Elsurer C,Selimoglu N,Yilmaz M,Erdogan E,Bengi Celik J,Kal O,Onal O

更新日期：2017-08-01 00:00:00

abstract：:In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessary step prior to in vivo testing. A MCL that accurately represents the physiology of the cardiovascular system accelerates the assessment of the device's ability to treat pathological conditions. To serve this purpose, a...

journal_title：Artificial organs

authors： Timms DL,Gregory SD,Greatrex NA,Pearcy MJ,Fraser JF,Steinseifer U

更新日期：2011-04-01 00:00:00

abstract：:Tissue engineering utilizes an interdisciplinary approach to generate constructs for the treatment and repair of diseased organs. Generation of small vessels as vascular grafts or as envisioned central vessel for vascularized constructs is still a challenge. Here, the decellularization of porcine vessels by a non-dete...

journal_title：Artificial organs

authors： Eyre K,Samper E,Haverich A,Hilfiker A,Andrée B

更新日期：2020-10-01 00:00:00

abstract：:Recently, the use of electrolyzed solutions has attracted considerable interest in Japan. This study investigates the efficiency of electrolyzed solutions as disinfecting agents (DA) in the reuse of dialyzers and compares their efficiency to that of other disinfectants currently in use. The following 3 methods were em...

journal_title：Artificial organs

authors： Tanaka N,Tanaka N,Fujisawa T,Daimon T,Fujiwara K,Yamamoto M,Abe T

更新日期：2000-12-01 00:00:00

abstract：:The major restrictions to the transport of solute and solvent across the peritoneum are the limited peritoneal blood flow, area and permeability. Recent investigations have demonstrated that several vasoactive drugs influence transport parameters. Isoproterenol, nitroprusside, dipyridamole and dopamine exemplify drugs...

journal_title：Artificial organs

authors： Maher JF

更新日期：1979-08-01 00:00:00

abstract：:The effectiveness of the blood substitute neo red cells (NRC) on hemorrhagic shock was evaluated in dogs. Shock was induced by bloodletting, and NRC was infused immediately until the dogs recovered from shock; the process was repeated 3 times (mild shock), or NRC was infused after shock was maintained for 30 min, and ...

journal_title：Artificial organs

authors： Usuba A,Osuka F,Kimura T,Sato R,Fujita Y,Yamashita M,Hoshino C

更新日期：1998-02-01 00:00:00

abstract：:Twelve patients, 8 male and 4 female, aged from 26 to 70 years were studied. They were on hemodialysis (HD) 4 h three times weekly with cuprophan hollow fiber dialyzers (Gambro 120M) and dialysate containing 35 mEq/L of acetate. The study compares two random HD sessions on each patient. Sixty minutes prior to one rand...

journal_title：Artificial organs

authors： Grekas D,Alivanis P,Karamouzis M,Pyrpasopoulos M,Tourkantonis A

更新日期：1989-10-01 00:00:00

abstract：:The nanocomposites (denoted "CII-Au") of porcine type II collagen (CII) with 0.05, 0.1, 0.5, 1, or 2.5% (wt/wt) Au nanoparticles ( approximately 5 nm) were fabricated for potential use in cartilage tissue engineering. Au formed clusters on the surface of all nanocomposites and appeared to distribute along the collagen...

journal_title：Artificial organs

authors： Hsu SH,Yen HJ,Tsai CL

更新日期：2007-12-01 00:00:00