The role of IFN-gamma in murine Salmonella typhimurium infection.

abstract：BACKGROUND:Brucella is a Gram-negative and facultative intracellular organism that causes brucellosis, a common zoonotic disease. Over 500,000 people are annually affected by brucellosis. Brucella is highly infectious through inhalation route; for this reason it is used for biological warfare aims. This study aimed to ...

journal_title：Microbial pathogenesis

authors： Abadi AH,Mahdavi M,Khaledi A,Esmaeili SA,Esmaeili D,Sahebkar A

更新日期：2018-08-01 00:00:00

abstract：:Food-production animals were considered to be a major reservoir of antimicrobial-resistant bacteria and clinically relevant pathogens. The potential of commensal Escherichia coli from pigs as a source of opportunistic pathogens associated with extraintestinal infections in humans needs to be assessed. In this study, 1...

journal_title：Microbial pathogenesis

authors： Li Y,Ma X,Li C,Dai X,Zhang L

更新日期：2020-11-01 00:00:00

abstract：:The bacterial phylum Synergistetes consists of Gram-negative anaerobes. Oral Synergistetes are divided in two main clusters, namely A and B. Increasing evidence demonstrates their involvement in etiology of oral infections, including apical periodontitis. This condition causes bone loss around the apex of the tooth, s...

journal_title：Microbial pathogenesis

authors： Fernandes Cdo C,Rechenberg DK,Zehnder M,Belibasakis GN

更新日期：2014-08-01 00:00:00

abstract：:The antigenic site normally situated in the EF loop of VP2 (2EF) of poliovirus type 2 (Lansing) [PV2 (L)] was expressed in 2EF or in the BC loop of VP1 (1BC) of PV1 (Mahoney) [PV1 (M)]. A hybrid virus expressing the site in 2EF of PV1 (M) is known to be neutralizable by PV2 (L)-specific antisera and to induce neutrali...

journal_title：Microbial pathogenesis

authors： Murdin AD,Mirzayan C,Kameda A,Wimmer E

更新日期：1991-01-01 00:00:00

abstract：:Protein D, having a glycerol-3-phosphodiester phosphodiesterase activity, is found at the surface of all Haemophilus influenzae strains and is a possible virulence factor. In the present study, the involvement of protein D in the entry of NTHi into human monocytic cells is reported. Primary monocytes and the monocytic...

journal_title：Microbial pathogenesis

authors： Ahrén IL,Janson H,Forsgren A,Riesbeck K

更新日期：2001-09-01 00:00:00

abstract：:A virus inhibitor found in gastric secretions and in extracts from gastrointestinal tissues is described. The inhibitor shares a number of characteristics with the recently described contact-blocking virus inhibitor (CVI), which is produced by unstimulated cells in culture, and occurs naturally in some body fluids. Th...

journal_title：Microbial pathogenesis

authors： Baron JL,Li JL,McKerlie ML,Shabot JM,Coppenhaver DH

更新日期：1986-06-01 00:00:00

abstract：:Mycobacterium tuberculosis genome encodes several high and low molecular mass penicillin binding proteins. One such low molecular mass protein is DacB2 encoded by open reading frame Rv2911 of M. tuberculosis which is predicted to play a role in peptidoglycan synthesis. In this study we have tried to gain an insight in...

journal_title：Microbial pathogenesis

authors： Bourai N,Jacobs WR Jr,Narayanan S

更新日期：2012-02-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is a common cause of hospital-acquired infection and has become an epidemic globally. Alpha-haemolysin (α-haemolysin), a pore-forming toxin, is one of the most important virulence factors secreted by most S. aureus strains. α-haemolysin monomers form a 232.4-kDa membrane-inserted hept...

journal_title：Microbial pathogenesis

authors： Zhou Y,Chen C,Pan J,Deng X,Wang J

更新日期：2018-02-01 00:00:00

abstract：:Oxidative stress is implicated in the pathogenesis of influenza virus infection. Increasing evidences show that transient receptor potential melastatin 2 (TRPM2), a Ca2+-permeable non-selective cation channel, plays an important role in the pathomechanism of reactive oxygen species (ROS)-coupled diseases. The present ...

journal_title：Microbial pathogenesis

authors： Wang S,Liang T,Luo Q,Li P,Zhang R,Xu M,Su J,Xu T,Wu Q

更新日期：2020-11-01 00:00:00

abstract：:In this paper, we have assessed the role of changing physicochemical parameters and substrate types on the production of α-amylase enzyme from Penicillium chrysogenum, with a view to determining the optimal conditions required for its maximum production. The findings of this research revealed that, at pH 6 using linse...

journal_title：Microbial pathogenesis

authors： Dar GH,Kamili AN,Nazir R,Bandh SA,Jan TR,Chishti MZ

更新日期：2015-11-01 00:00:00

abstract：:Oropharyngeal candidiasis is a frequent opportunistic infection associated with immunocompromised hosts. Candida albicans is the principal species responsible for this infection. Production of interleukin-8 (IL-8), by oral epithelial cells can be expected to play a major role in the recruitment and activation of profe...

journal_title：Microbial pathogenesis

authors： Dongari-Bagtzoglou A,Kashleva H

更新日期：2003-04-01 00:00:00

abstract：:Respiratory infections caused by nontypeable Haemophilus influenzae (NTHi) are a major medical problem. Evidence suggests that the ability to form biofilms on mucosal surfaces may play a role in NTHi pathogenesis. However, the factors that contribute to NTHi biofilm cohesion remain largely unknown. In this study we in...

journal_title：Microbial pathogenesis

authors： Izano EA,Shah SM,Kaplan JB

更新日期：2009-04-01 00:00:00

abstract：:The corticosteroid-treated animal is well established as an experimental model for the study of Pneumocystis carinii pneumonitis (PCP). Latent or acquired infection with P. carinii in the murine lung progresses to fatal pneumonitis when the host is profoundly immunocompromized. In this study the effects of five immuno...

journal_title：Microbial pathogenesis

authors： Oz HS,Hughes WT,Rehg JE,Thomas EK

更新日期：2000-09-01 00:00:00

abstract：:Little is known about the virulence factors of Burkholderia mallei, the etiologic agent of glanders. We employed subtractive hybridization to identify genetic determinants present in B. mallei but not in Burkholderia thailandensis, a non-pathogenic soil microbe. Three subtractive hybridization products were mapped to ...

journal_title：Microbial pathogenesis

authors： DeShazer D,Waag DM,Fritz DL,Woods DE

更新日期：2001-05-01 00:00:00

abstract：:Chronic hepatitis B (CHB) infection is a typical inflammatory disease characterized by a dysregulated expression of cytokines, which contributes to the pathogenesis of chronic Hepatitis B virus (HBV) infection. IL-36 cytokines (IL-36α, IL-36β, IL-36γ and IL-36Ra) are important players in infection and immunity. Howeve...

journal_title：Microbial pathogenesis

authors： Gong Y,Tingxi Z,Qing L,Guozhen Z,Bing T,Xiaoliang Y,Yan W,Wenjuan J,Yan X,Hui L,Xue H,Zebo Y

更新日期：2017-12-01 00:00:00

abstract：:The Aeromonas genus has several virulence factors associated with the development of diseases in aquatic organisms, leading to losses in aquaculture. One of these factors is the flagella's formation which allows the biofilm's formation that provides the microorganisms a greater pathogenicity, greater protection to cer...

journal_title：Microbial pathogenesis

authors： Freire NB,Magalhães TC,Nunes Soares RA,da Costa MM,Gouveia GV

更新日期：2019-02-01 00:00:00

abstract：:Mannheimia(Pasteurella)haemolytica serotype 1 is the primary causative agent responsible for bovine pneumonic mannheimiosis, also known as shipping fever in cattle. The bacterium produces a variety of virulence factors, foremost of which is the exotoxic leukotoxin. The leukotoxin is a calcium-dependent cytolysin that ...

journal_title：Microbial pathogenesis

authors： Thumbikat P,Briggs RE,Kannan MS,Maheswaran SK

更新日期：2003-05-01 00:00:00

abstract：:Stored rice and rice products are prone to contamination by pathogenic fungi and bacteria such as Aspergillus niger, Bacillus cereus, and Paenibacillus amylolyticus. Treatment with antimicrobial essential oils (EOs) and irradiation are options to control spoilage organisms. Microbial samples with or without fumigation...

journal_title：Microbial pathogenesis

authors： Shankar S,Follett P,Ayari S,Hossain F,Salmieri S,Lacroix M

更新日期：2020-06-01 00:00:00

abstract：:The type III secretion system of Pseudomonas aeruginosa, responsible for acute infection, is composed of over twenty proteins that facilitate cytotoxin injection directly into host cells. Integral to this process is production and secretion of PcrV. Administration of a recently developed, anti-PcrV immunoglobulin, eit...

journal_title：Microbial pathogenesis

authors： Lynch SV,Flanagan JL,Sawa T,Fang A,Baek MS,Rubio-Mills A,Ajayi T,Yanagihara K,Hirakata Y,Kohno S,Misset B,Nguyen JC,Wiener-Kronish JP

更新日期：2010-06-01 00:00:00

abstract：:Roselle, or Jamaica sorrel (Hibiscus sabdariffa) is a popular vegetable in many tropical regions, cultivated for its leaves, seeds, stems and calyces which, the dried calyces are used to prepare tea, syrup, jams and jellies and as beverages. The main objectives of this study were to identify and characterise fungal pa...

journal_title：Microbial pathogenesis

authors： Eslaminejad T,Zakaria M

更新日期：2011-11-01 00:00:00

abstract：:The enteropathogenic potential of 32 Vibrio cholerae O1 isolates that do not produce cholera toxin was examined in the orally inoculated, sealed adult mouse model. Live cultures (2 x 10(10) cfu/ml) of 7/16 clinical and 6/16 environmental isolates produced a positive intestinal fluid accumulation (FA) ratio that reache...

journal_title：Microbial pathogenesis

authors： Moyenuddin M,Wachsmuth K,Richardson SH,Cook WL

更新日期：1992-06-01 00:00:00

abstract：:The non-fimbrial adhesin NFA-4 from uropathogenic Escherichia coli O7:K98:H6 mediates the agglutination of human red cells (RBC), notably of blood group MM. The adhesin can be separated from the bacteria by heat extraction and was purified to homogeneity by ammonium sulphate precipitation and anion exchange chromatogr...

journal_title：Microbial pathogenesis

authors： Hoschützky H,Nimmich W,Lottspeich F,Jann K

更新日期：1989-05-01 00:00:00

abstract：:Helicobacter pylori (H. pylori) usually colonizes the gastric mucosa of more than 50% of the human population, causing an infection that may appear in early childhood and can persist for life. H. pylori is suggested as the main cause of peptic ulcer and chronic gastritis. It is also associated with gastric cancer. Its...

journal_title：Microbial pathogenesis

authors： Bagheri N,Azadegan-Dehkordi F,Rafieian-Kopaei M,Rahimian G,Asadi-Samani M,Shirzad H

更新日期：2016-11-01 00:00:00

abstract：:Opa-expressing variants of Neisseria gonorrhoeae strain F62-SF and an Opa- variant, all non-piliated, were examined for differences in the interaction of the bacteria within colonies and in attachment to and damage of human fallopian tube mucosa. Expression of certain Opas was associated with the formation of transpar...

journal_title：Microbial pathogenesis

authors： Dekker NP,Lammel CJ,Mandrell RE,Brooks GF

更新日期：1990-07-01 00:00:00

abstract：:Endometritis is commonly occurred in dairy cows after calving and results in a great deal of property damage. Although numerous studies have been performed to find the therapeutic agents for endometritis, the incidence of this disease remains high. Short-chain fatty acids (SCFAs), the major metabolic products of anaer...

journal_title：Microbial pathogenesis

authors： Guo J,Wang Y,Jiang P,Yao H,Zhao C,Hu X,Cao Y,Zhang N,Fu Y,Shen H

更新日期：2019-12-01 00:00:00

abstract：:Three coagulase-negative Staphylococcus species (CNS) (Staphylococcus epidermidis, Staphylococcus xylosus and Staphylococcus hyicus), from the milk of cows with mastitis, were used to evaluate adherence to and internalization by bovine mammary epithelial cells, and to investigate involvement of host cell signal transd...

journal_title：Microbial pathogenesis

authors： Almeida RA,Oliver SP

更新日期：2001-11-01 00:00:00

abstract：:Bacillus halotolerans is a rhizobacterium with the potential to promote plant growth and tolerance to drought and salinity stress. Here, we present the complete genome sequence of B. halotolerans ZB201702, which consists of 4,150,000 bp in a linear chromosome, including 3074 protein-coding sequences, 30 rRNAs, and 85 ...

journal_title：Microbial pathogenesis

authors： Zhang Z,Yin L,Li X,Zhang C,Liu C,Wu Z

更新日期：2018-10-01 00:00:00

abstract：:A novel N-acyl substituted indole-linked benzimidazoles and naphthoimidazoles were synthesized. Their chemical structures were confirmed using spectroscopic tools including 1H NMR, 13C NMR and CHN-elemental analyses. Anti inflammatory activity for all target compounds was evaluated in-vitro. The synthesized compounds ...

journal_title：Microbial pathogenesis

authors： Abraham R,Prakash P,Mahendran K,Ramanathan M

更新日期：2018-01-01 00:00:00

abstract：:The reactivity of anti-pilus antibodies to native and denatured Haemophilus influenzae b (Hib) pili was studied using rabbit serum prepared against piliated H. influenzae b strain M43 (p+) and adsorbed with its non-piliated variant, strain M42 (p-). The specificity of the adsorbed serum for Hib pili was documented by ...

journal_title：Microbial pathogenesis

authors： Gilsdorf JR,Forney LJ,LiPuma JJ

更新日期：1989-10-01 00:00:00

abstract：:The major limitation in histological examination of orally inoculated mice of Salmonella typhimurium has been the difficulty of attaining high enough levels for immunochemical detection. This problem has been solved by the use of confocal laser scanning microscopy (CLSM) analysis, which allows detection of bacteria in...

journal_title：Microbial pathogenesis

authors： Matsui H,Eguchi M,Kikuchi Y

更新日期：2000-07-01 00:00:00