Elevated production of IL-36α in chronic hepatitis B virus-infected patients correlates with viral load.

abstract：:An mdaB mutant strain in a quinone reductase (MdaB) of Helicobacter hepaticus type strain ATCC51449 was constructed by insertional mutagenesis, and the MdaB protein was purified and compared to the Helicobacter pylori enzyme. While wild type H. hepaticus cells could tolerate 6% O(2) for growth, the mdaB strain was cle...

journal_title：Microbial pathogenesis

authors： Hong Y,Wang G,Maier RJ

更新日期：2008-02-01 00:00:00

abstract：:A number of different techniques were used to analyse classic and atypical serogroup O:11 Aeromonas isolates. Five of seven atypical O:11, S layer-negative strains lacking a homogeneous LPS side-chain pattern exhibited varying degrees of mouse pathogenecity. One virulent atypical strain (AH-77) synthesized a surface a...

journal_title：Microbial pathogenesis

authors： Kokka RP,Vedros NA,Janda JM

更新日期：1991-01-01 00:00:00

abstract：:The IrgA homolog adhesin (Iha) is an adherence-conferring outer membrane protein of Escherichia coli associated with enterohemorrhagic and uropathogenic strains. Here, we used primer extension analysis to identify iha promoters in O157:H7 and uropathogenic E. coli strains. Transcriptional fusions demonstrated that iha...

journal_title：Microbial pathogenesis

authors： Rashid RA,Tarr PI,Moseley SL

更新日期：2006-12-01 00:00:00

abstract：:Upon oxygen shift-down, Mycobacterium tuberculosis complex bacteria can induce a genetic program characterized by halted duplication, which is called Non-replicating persistence (NRP). During this phase, at least 48 genes, collectively named Dormancy survival regulator (DosR) regulon, are important for the long-term s...

journal_title：Microbial pathogenesis

authors： Jiménez BA,Hinojoza-Loza E,Flores-Valdez MA,Prado-Montes de Oca E,Allen K,Estrada-Chávez C,Herrera-Rodríguez S,Flores-Fernández JM,Martínez-Velázquez M,Hernández-Gutiérrez R,Alvarez AH

更新日期：2013-08-01 00:00:00

abstract：:Sigma factor B (SigB) controls the expression of Staphylococcus aureus genes including virulence factors and plays a role in the bacterial secretion system through membrane vesicle production. Inhibition of SigB could attenuate SigB dependent virulence and secretion system. The objective of this study was to determine...

journal_title：Microbial pathogenesis

authors： Mitsuwan W,Jiménez-Munguía I,Visutthi M,Sianglum W,REIPI\/GEIH Study Group.,Rodríguez-Ortega MJ,Voravuthikunchai SP

更新日期：2019-03-01 00:00:00

abstract：:Binding of human enterotoxigenic Escherichia coli (ETEC) to the small intestine is a prerequisite for colonization and is mediated by colonization factor (CF) antigens. Coli surface antigen 6 (CS6) is considered a CF but binding to isolated enterocytes has not been established. In this study bacteria expressing CS6 we...

journal_title：Microbial pathogenesis

authors： Helander A,Hansson GC,Svennerholm AM

更新日期：1997-12-01 00:00:00

abstract：:Crohn's disease (CD) is characterized by a pathogenic intestinal inflammation mediated by a Th1-skewed immune system and a dysregulated intestinal mucosal community. In this study, we investigated the role of bacteria on the activation and function of monocytes, and its association with CD pathogenesis. To this end, f...

journal_title：Microbial pathogenesis

authors： Gu J,Liu G,Xing J,Song H,Wang Z

更新日期：2018-08-01 00:00:00

abstract：:The gene clusters encoding various P-fimbriae (F7(1), F7(2), F9 and F11) were compared. Deletion plasmids that lack the gene encoding the fimbrillin were derived from these gene clusters. Introduction of these deletion plasmids into an E. coli K12 strain resulted in non-fimbriated cells that still showed mannose-resis...

journal_title：Microbial pathogenesis

authors： van Die I,Zuidweg E,Hoekstra W,Bergmans H

更新日期：1986-02-01 00:00:00

abstract：:The mechanism of Cronobacter pathogenesis in neonatal meningitis and potential virulence factors (aside from host cell invasion ability) remain largely unknown. To ascertain whether Cronobacter can invade and transcytose across intestinal epithelial cells, enter into the blood stream and then transcytose across the bl...

journal_title：Microbial pathogenesis

authors： Giri CP,Shima K,Tall BD,Curtis S,Sathyamoorthy V,Hanisch B,Kim KS,Kopecko DJ

更新日期：2012-02-01 00:00:00

abstract：:In this study experimental mouse model for Chlamydia pneumoniae infection was used to elucidate the nature of immune response developing during primary and secondary infection. First we examined the mononuclear cells from different lymphoid organs in BALB/c mice during C. pneumoniae infection and detected a strong lym...

journal_title：Microbial pathogenesis

authors： Kyläniemi MK,Haveri A,Vuola JM,Puolakkainen M,Lahesmaa R

更新日期：2009-05-01 00:00:00

abstract：:The re-emerging field of phage therapy is the potential biocontrol agents for the transfer of virulence factor and to kill their bacterial hosts. In this study, the lytic Vibrio vulnificus phages were studied to provide a better understanding of phage-host interactions and development of phage therapy. Four new V. vul...

journal_title：Microbial pathogenesis

authors： Srinivasan P,Ramasamy P

更新日期：2017-10-01 00:00:00

abstract：:We have described a new class of live attenuated salmonella vaccines harbouring lesions in htrA, a stress protein gene previously. The virulence and invasiveness of Salmonella htrA mutants was investigated in three models of increased susceptibility to Salmonella infection. These included BALB/c mice, either given sub...

journal_title：Microbial pathogenesis

authors： Strahan K,Chatfield SN,Tite J,Dougan G,Hormaeche CE

更新日期：1992-04-01 00:00:00

abstract：:Mannheimia(Pasteurella)haemolytica serotype 1 is the primary causative agent responsible for bovine pneumonic mannheimiosis, also known as shipping fever in cattle. The bacterium produces a variety of virulence factors, foremost of which is the exotoxic leukotoxin. The leukotoxin is a calcium-dependent cytolysin that ...

journal_title：Microbial pathogenesis

authors： Thumbikat P,Briggs RE,Kannan MS,Maheswaran SK

更新日期：2003-05-01 00:00:00

abstract：:The present study was aimed to assess the prevalence and efficiency of techniques for the diagnosis of bovine tuberculosis (bTB) including enzyme-linked immunosorbent assay (ELISA), Gamma interferon assay (IFN-γ) and polymerase chain reaction (PCR) in comparison to skin tuberculin test and culture technique. A total o...

journal_title：Microbial pathogenesis

authors： Algammal AM,Wahdan A,Elhaig MM

更新日期：2019-09-01 00:00:00

abstract：:The antimicrobial resistance (AMR) exhibited against broad spectrum and new generation antibiotics used for Pseudomonas infections is a major threat and renders the treatment ineffective. In our present study, we have used a computational approach to understand various drug resistance mechanisms which contribute to Mu...

journal_title：Microbial pathogenesis

authors： Miryala SK,Anbarasu A,Ramaiah S

更新日期：2019-11-01 00:00:00

abstract：:The antigenic site normally situated in the EF loop of VP2 (2EF) of poliovirus type 2 (Lansing) [PV2 (L)] was expressed in 2EF or in the BC loop of VP1 (1BC) of PV1 (Mahoney) [PV1 (M)]. A hybrid virus expressing the site in 2EF of PV1 (M) is known to be neutralizable by PV2 (L)-specific antisera and to induce neutrali...

journal_title：Microbial pathogenesis

authors： Murdin AD,Mirzayan C,Kameda A,Wimmer E

更新日期：1991-01-01 00:00:00

abstract：:Staphylococcus aureus is a bacterial pathogen causing approximately 80% of all cases of human osteomyelitis. This bacterium can adhere to and become internalized by osteoblasts and previous studies indicate that osteoblasts are active in the internalization process. In the current study, we examined the roles of micro...

journal_title：Microbial pathogenesis

authors： Ellington JK,Reilly SS,Ramp WK,Smeltzer MS,Kellam JF,Hudson MC

更新日期：1999-06-01 00:00:00

abstract：:This study aims to investigate whether IL-10 regulate decidual Treg cells apoptosis to reverse the abnormal pregnancy outcomes with Toxoplasma gondii (T. gondii) infection. Recombinant mouse IL-10 (rIL-10) treatment and IL-10 deficiency (IL-10(-/-)) abnormal pregnancy animal models with T. gondii infection were establ...

journal_title：Microbial pathogenesis

authors： Lao K,Zhao M,Li Z,Liu X,Zhang H,Jiang Y,Wang Y,Hu X

更新日期：2015-12-01 00:00:00

abstract：:The aim of this study was to use fluorescence in-situ hybridisation (FISH) to search for the tissues and cell types important in survival and persistence of Mycoplasma haemofelis, "Candidatus Mycoplasma haemominutum" or "Candidatus Mycoplasma turicensis" in infected cats. A 16S rDNA probe for each species was applied ...

journal_title：Microbial pathogenesis

authors： Peters IR,Helps CR,Willi B,Hofmann-Lehmann R,Gruffydd-Jones TJ,Day MJ,Tasker S

更新日期：2011-02-01 00:00:00

abstract：:The Gram-positive bacterium Group B Streptococcus (GBS) is an important cause of serious neonatal and adult infections. Toll-like receptor 2 (TLR2) recognizes components of the cell wall of Gram-positive bacteria and is critical for defense against certain invasive pathogens. In GBS, penicillin-binding protein 1a (PBP...

journal_title：Microbial pathogenesis

authors： Asplin IR,Carl DJ,Way SS,Jones AL

更新日期：2008-01-01 00:00:00

abstract：:Streptococcus suis is an important pathogen in swine, and it also represents an emerging zoonotic agent. Zebrafish as a model for the evaluation of virulence of S. suis has been demonstrated before. Here, an Affymetrix Zebrafish GeneChip was used to identify alterations in gene expression of zebrafish injected with S....

journal_title：Microbial pathogenesis

authors： Wu Z,Zhang W,Lu Y,Lu C

更新日期：2010-05-01 00:00:00

abstract：:The pathogenesis and development of ankylosing spondylitis (AS) is concealed and complicated. In recent years, alterations in gut microbiota of AS patients have been largely investigated, although the underlying mechanisms remain unclear. This article reviews the recent studies on changes of gut microbiota in AS patie...

journal_title：Microbial pathogenesis

authors： Zhang L,Hu Y,Xu Y,Li P,Ma H,Li X,Li M

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of occurrence of Mycoplasma genitalium infection in the peritoneal fluid of infertile women as compared to fertile women. MATERIALS AND METHODS:We have selected 162 infertile women aged 22-40 years as study subject and 162 women posted for elective caesarean section, were taken as ...

journal_title：Microbial pathogenesis

authors： Rekha S,Nooren M,Kalyan S,Mohan M,Bharti M,Monika R,Anita S,Kiran M,Vandana N

更新日期：2019-04-01 00:00:00

abstract：:The clinical implications of recently discovered porcine circovirus 3 (PCV3) infections are still unknown. The potential role of this emerging virus in reproductive loss in swine has been described. Herein, we report a high prevalence of PCV3 in mummified fetuses from sows maintained in modern farms in Rio Grande do S...

journal_title：Microbial pathogenesis

authors： Dal Santo AC,Cezario KC,Bennemann PE,Machado SA,Martins M

更新日期：2020-04-01 00:00:00

abstract：:Recently, microbial exopolysaccharides (EPSs) have offered very large field for medical applications owing to their bioactive characteristics. This study aimed to obtain antitumor EPS and to optimize its production using different optimization approaches. Eighty EPSs-producing bacteria were obtained from mud samples. ...

journal_title：Microbial pathogenesis

authors： Farag MMS,Moghannem SAM,Shehabeldine AM,Azab MS

更新日期：2020-03-01 00:00:00

abstract：:Group A streptococci demonstrate a number of distinct ways to interact with the human fibrinolytic system to acquire unregulatable cell-surface enzymatic activity. Interactions between bacteria, fibrinogen, streptokinase and plasminogen resulted in acquisition of cell-associated enzymatic activity that can lyse fibrin...

journal_title：Microbial pathogenesis

authors： Wang H,Lottenberg R,Boyle MD

更新日期：1995-03-01 00:00:00

abstract：:In the amino acid (AA) sequences of alpha antigen from mycobacteria, C-terminal regions were variable among a variety of mycobacterial species though the N-terminal regions were relatively conserved. These regions may possess some species-specific antigenic determinants of the alpha antigen from Mycobacterium scrofula...

journal_title：Microbial pathogenesis

authors： Takano M,Ohara N,Naito M,Matsumoto S,Matsuo T,Shirai R,Mizuno A,Yamada T

更新日期：1997-08-01 00:00:00

abstract：:Toxoplasma gondii is one of the most successful intracellular protozoan parasites in the world, which can infect most warm-blooded animals including foxes in the world and cause toxoplasmosis. This is the first meta-analysis to assess the overall prevalence and potential risk factors of T. gondii among foxes in the wo...

journal_title：Microbial pathogenesis

authors： Wei XY,Gao Y,Lv C,Wang W,Chen Y,Zhao Q,Gong QL,Zhang XX

更新日期：2020-12-28 00:00:00

abstract：:The non-fimbrial adhesin NFA-4 from uropathogenic Escherichia coli O7:K98:H6 mediates the agglutination of human red cells (RBC), notably of blood group MM. The adhesin can be separated from the bacteria by heat extraction and was purified to homogeneity by ammonium sulphate precipitation and anion exchange chromatogr...

journal_title：Microbial pathogenesis

authors： Hoschützky H,Nimmich W,Lottspeich F,Jann K

更新日期：1989-05-01 00:00:00

abstract：:Many virulence genes have been reported to play important roles in Helicobacter pylori pathogenesis. However the detailed mechanisms of many of them have not been completely clear. In this study, we found gene hp0169, encoding a putative collagenase (HpPrtC), was involved in pathogenesis of H. pylori. Recombinant HpPr...

journal_title：Microbial pathogenesis

authors： Zhao H,Ji X,Chen X,Li J,Zhang Y,Du Z,Zhang Y,Li B

更新日期：2017-03-01 00:00:00