Circ_LAS1L regulates cardiac fibroblast activation, growth, and migration through miR-125b/SFRP5 pathway.

abstract：:The possibility that inositol lipid metabolism is related to nuclear events accompanying steroid hormone action has been investigated by comparing lipid phosphorylation and breakdown in normal rat liver nuclei and in hypo- and hypercortisolemic conditions. Lipid phosphorylation in vitro showed the presence of diacylgl...

journal_title：Cell biochemistry and function

authors： Santi P,Marmiroli S,Falcieri E,Bertagnolo V,Capitani S

更新日期：1994-09-01 00:00:00

abstract：:The main purpose of the present investigation was to study the effect of cloturin on aerobic glycolysis, endogenous and exogenous respiration and the level of ATP in both Ehrlich ascites carcinoma (EAC) and P388 murine leukaemia cells incubated in vitro. Also its effect on the level of total (T-SH) and non-protein (NP...

journal_title：Cell biochemistry and function

authors： Miko M,Krepelka J,Melka M

更新日期：1992-06-01 00:00:00

abstract：:The melastatin-related transient receptor potential channel TRPM2 is a plasma membrane Ca(2+)-permeable cation channel that is activated by hydrogen peroxide (H(2)O(2)) as a consequence of oxidative stress although the channel activation by H(2)O(2) appears to represent a cell-specific process in cells with endogenous...

journal_title：Cell biochemistry and function

authors： Naziroğlu M,Lückhoff A,Jüngling E

更新日期：2007-07-01 00:00:00

abstract：:The aim of this brief communication was to determine the correlation between pre-eclampsia (PE), Helicobacter pylori pathogenic strains seropositivity, and interleukin-18 (IL-18) levels. To this purpose 25 pre-eclamptic women and 25 healthy parturient women of similar age were evaluated for: IL-18 levels, by ELISAH. p...

journal_title：Cell biochemistry and function

authors： Pugliese A,Beltramo T,Todros T,Cardaropoli S,Ponzetto A

更新日期：2008-10-01 00:00:00

abstract：:The gene expression of heme oxygenase-1 (HO-1) was studied in mammalian cell lines exposed to hyperoxia. Northern blot analysis demonstrated that hyperoxic exposure increased the HO-1 mRNA levels in various types of cells, including human hepatoma (HepG2) cells. This increase was time- and dose-dependent, and reversib...

journal_title：Cell biochemistry and function

authors： Takahashi S,Takahashi Y,Yoshimi T,Miura T

更新日期：1998-09-01 00:00:00

abstract：:The dietary administration of selenium (sodium selenite; 4 p.p.m.) daily has been found to be highly effective in reducing the incidence of cancer induced by N-nitrosodiethylamine (DEN) in Wistar strain rats. Selenium treatment either before initiation, during initiation and selection/phenobarbital promotion phases of...

journal_title：Cell biochemistry and function

authors： Thirunavukkarasu C,Prince Vijeya Singh J,Thangavel M,Selvendiran K,Sakthisekaran D

更新日期：2002-12-01 00:00:00

abstract：:The biochemical and quantitative cytochemical assays of the activity of uridine diphosphoglucose dehydrogenase (UDPG-D) have produced perplexing results. It is now shown that the perplexity may be due to the possibility that the coenzyme (NAD) required for UDPG-D activity, may be acting as a substrate for a second deh...

journal_title：Cell biochemistry and function

authors： Mehdizadeh S,Bitensky L,Chayen J

更新日期：1991-04-01 00:00:00

abstract：:Nuclear, chromatin and microsomal fractions were isolated from hepatocytes prepared from rats injected with [32P]O4(2-) and killed subsequently at times between 1 and 48 h. Specific activities of the total phospholipids (PL) were determined for each subcellular fraction. The major points noted were the initial specifi...

journal_title：Cell biochemistry and function

authors： Viola-Magni MP,Gahan PB,Albi E,Iapoce R,Gentilucci PF

更新日期：1986-10-01 00:00:00

abstract：:Human cytochrome P450 2J2 (CYP2J2) is abundant in cardiovascular tissue and active in the metabolism of arachidonic acid to eicosanoids that have potent vasodilatory properties. Variability of the CYP2J2 gene is highly constrained except for its proximal promoter: there is a relatively common and functionally relevant...

journal_title：Cell biochemistry and function

authors： Takeshita H,Tsubota E,Takatsuka H,Kunito T,Fujihara J

更新日期：2008-10-01 00:00:00

abstract：:Glioblastoma is one of the most malignant tumors and causes the high mortality in cancer patients. Currently, there is no highly efficient therapy against glioblastoma. Therefore, searching for a new molecular target to anti-glioblastoma therapy is urgent and necessary. In this study, we elucidated the role of Signal ...

journal_title：Cell biochemistry and function

authors： Zhao L,Li X,Su J,Wang Gong F,Lu J,Wei Y

更新日期：2020-07-01 00:00:00

abstract：:Because of limited treatment options, preeclampsia (PE) is the leading cause of perinatal morbidity and mortality worldwide. Recently, lncRNA TDRG1 is reported to be aberrantly down-regulated in PE placenta, and the abnormal expression of TDRG1 might play a key or partial role in PE development. In this study, we foun...

journal_title：Cell biochemistry and function

authors： Gong F,Cheng H,Shi Y,Cui L,Jia G

更新日期：2020-06-01 00:00:00

abstract：:We report a functional characterisation of the novel protein MGC13096. MGC13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1),...

journal_title：Cell biochemistry and function

authors： Chen Q,Yan C,Yan Q,Feng L,Chen J,Qian K

更新日期：2008-03-01 00:00:00

abstract：:Chemotherapeutic drugs that induce DNA damage have the potential to kill cancer cells, but DNA repair protects cells from damage-induced cell death. Thus, eliminating DNA repair is a potential approach to overcome cell drug resistance. In this study, we observed that the gene expression of C-terminal binding protein i...

journal_title：Cell biochemistry and function

authors： Yang L,Yang B,Wang Y,Liu T,He Z,Zhao H,Xie L,Mu H

更新日期：2019-10-01 00:00:00

abstract：:While transcription plays an obviously important role in gene expression, translation has recently been emerged as a key step that defines the composition and quality of the proteome in the cell of higher eukaryotes including mammals. Selective translation is supposed to be regulated by the structural heterogeneity of...

journal_title：Cell biochemistry and function

authors： Muto A,Sugihara Y,Shibakawa M,Oshima K,Matsuda T,Nadano D

更新日期：2018-08-01 00:00:00

abstract：:Incidence and mortality rates of cancer continue to increase greatly despite the improved diagnostic and therapeutic methods. Based on GLOBOCAN estimates, the numbers of new cancer cases reported in 2018 were ~18.1 million, while the numbers of cancer mortalities were ~9.6 million. It remains difficult to diagnose mos...

journal_title：Cell biochemistry and function

authors： El-Ashmawy NE,Al-Ashmawy GM,Hamouda SM

更新日期：2020-11-06 00:00:00

abstract：:Effects of methotrexate (MTX) on mitochondrial oxidative metabolism and ion transport were studied. MTX decreases the membrane potential (delta psi) upon energization of the mitochondrial membrane by NAD+-linked substrates and decreases the amplitude and velocity of swelling induced by glutamate and alpha-ketoglutarat...

journal_title：Cell biochemistry and function

authors： Yamamoto N,Lopes LC,Campello AP,Klüppel ML

更新日期：1989-04-01 00:00:00

abstract：:The aim of the present study was to measure plasma uric acid (UA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and xanthine oxidase (XO) activities and to evaluate the relationship between these parameters and the severity of pre-eclampsia. Twenty-five pre-eclamptic, 15 healthy pregnant and 1...

journal_title：Cell biochemistry and function

authors： Yildirim A,Altinkaynak K,Aksoy H,Sahin YN,Akcay F

更新日期：2004-07-01 00:00:00

abstract：:The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated with Δ(9)-tetrahydrocannabinol (Δ(9)-THC). Rats were randomly divided into four groups: control, Δ(...

journal_title：Cell biochemistry and function

authors： Coskun ZM,Bolkent S

更新日期：2014-10-01 00:00:00

abstract：:Epidermal growth factor plays a major role in breast cancer cell proliferation, survival, and metastasis. Quercetin, a bioactive flavonoid, is shown to exhibit anticarcinogenic effects against various cancers including breast cancer. Hence, the present study was designed to evaluate the effects of gold nanoparticles-c...

journal_title：Cell biochemistry and function

authors： Balakrishnan S,Mukherjee S,Das S,Bhat FA,Raja Singh P,Patra CR,Arunakaran J

更新日期：2017-06-01 00:00:00

abstract：:Several polymorphisms in the CYP1A1 locus have been identified and their genotypes appear to exhibit population frequencies that depend on ethnicity. We studied two CYP1A1 polymorphic sites (position 4889 and 6235) in a group of 212 unrelated healthy individuals belonging to three different Mexican populations (106 Me...

journal_title：Cell biochemistry and function

authors： Fragoso JM,Juárez-Cedillo T,Hernández-Pacheco G,Ramírez E,Zuñiga J,Izaguirre R,de la Peña A,Granados J,Vargas-Alarcón G

更新日期：2005-05-01 00:00:00

abstract：:The aim of this work was to determine the role of intraperitoneally-administered vitamin E and selenium on the biochemical and haematological parameters in the blood of rats. Thirty-two adult male Wistar rats were used in this study. All rats were randomly divided into four groups. The first group was used as the cont...

journal_title：Cell biochemistry and function

authors： Cay M,Naziroğlu M

更新日期：1999-06-01 00:00:00

abstract：:The phospholipid profiles of the myocardium (from 10- and 18-day old chick embryos and 13-day old chick) and their in vitro response to the endogenous lipolytic enzymes (mainly of the phospholipase group) at pH 7.4 and 38 degrees C for 60 min were analyzed by TLC technology and densitometry. Cardiolipin (CL) was shown...

journal_title：Cell biochemistry and function

authors： Helmy FM,Aikins A,Hughes J,Belfield C,Juracka A

更新日期：2007-09-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is an endothelium-specific mitogen and a promising inducer of angiogenesis and lymphangiogenesis. The VEGF receptors on endothelial cell membrane include the tyrosine kinases VEGFR-1 (Flt-1), VEGFR-2 (Flk-1/KDR) and VEGFR-3 (Flt-4). KDR is a major mediator of mitogenic, angiog...

journal_title：Cell biochemistry and function

authors： Ge X,Zhao L,He L,Chen W,Li X

更新日期：2012-03-01 00:00:00

abstract：:Organochalcogens are extensively produced and employed by industry and agriculture, and the risk of occupational and environmental toxicity to them has been poorly understood. Here, we investigated the acute effect of a new organochalcogen 3-methyl-1-phenyl-2-(phenylseleno)oct-2-en-1-one on biochemical and hematologic...

journal_title：Cell biochemistry and function

authors： dos Santos Lacerda D,de Oliveira Castro V,Mascarenhas M,Guerra RB,Dani C,Coitinho A,Gomez R,Funchal C

更新日期：2012-06-01 00:00:00

abstract：:We studied the effect of PTH (10-100 nM) on transductive mechanisms (adenylate cyclase activity, Ca2+ metabolism, IP3 levels) in cell cultures derived from normal and otosclerotic human bone fragments. The cultured cells were osteoblast-like but with calcitonin-receptors still present and with PTH receptors coupled wi...

journal_title：Cell biochemistry and function

authors： Fanó G,Venti-Donti G,Belia S,Paludetti G,Antonica A,Donti E,Maurizi M

更新日期：1993-12-01 00:00:00

abstract：:Scanning and integrating microdensitometry of azure B- and Coomassie brilliant blue G-stained tissue sections was used to measure the levels of RNA and protein, respectively, in pyramidal neurons of the insular cortex (INS) and midfrontal gyrus (MFG) in patients with Alzheimer's disease (AD) and age-matched, nondement...

journal_title：Cell biochemistry and function

authors： Colurso GJ,Kan RK,Anthony A

更新日期：1995-12-01 00:00:00

abstract：:The aim of this study was to evaluate the role of mitochondria in the recovery of cardiac energetics induced by ischaemic preconditioning at reperfusion. Isolated rat hearts were aerobically perfused (control), subjected to global ischaemia and reperfusion (reperfusion), or subjected to 3 brief cycles of ischaemia/rep...

journal_title：Cell biochemistry and function

authors： Muscari C,Bonafè F,Gamberini C,Giordano E,Lenaz G,Caldarera CM

更新日期：2006-11-01 00:00:00

abstract：:Hyperglycemia induces overproduction of superoxide and it is related to diabetic complications. In this study, we analyzed the antioxidant enzymatic defense and the lipid peroxidation of rat salivary glands in six different periods of diabetic condition. Ninety-six rats were divided into 12 groups: C7/14/21/28/45/60 (...

journal_title：Cell biochemistry and function

authors： Ibuki FK,Simões A,Nogueira FN

更新日期：2010-08-01 00:00:00

abstract：:Rat liver mitochondria were stored at 0-4 degrees C for several days using an appropriate medium and energy source. The elimination of the majority of microsomes and lysosomes, that normally contaminate isolated mitochondria, had a positive effect in preservation of respiratory control, P:O ratio, and monoamine oxidas...

journal_title：Cell biochemistry and function

authors： Higuti IH,Murata LY,Stencel M,De Paiva Campello A,Do Nascimento AJ

更新日期：1985-10-01 00:00:00

abstract：:Specific binding of a fully biologically active 125I-gonadotrophin releasing hormone (GnRH) to isolated anterior pituitary cells is time dependent, saturable and the concentration dependent binding curves exhibit positive cooperativity. Binding to intact or solubilized plasma membranes and an affinity purified GnRH re...

journal_title：Cell biochemistry and function

authors： Zolman JC,Theodoropoulos TJ

更新日期：1984-10-01 00:00:00