The novel MGC13096 protein is correlated with proliferation.

Abstract:

:We report a functional characterisation of the novel protein MGC13096. MGC13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1), cAMP response element binding protein (CREB), nuclear factor of activated T cells (NFAT), NF-kappaB, signal transducer and activator of transcription 1 (STAT1) took part in the process.

journal_name

Cell Biochem Funct

authors

Chen Q,Yan C,Yan Q,Feng L,Chen J,Qian K

doi

10.1002/cbf.1410

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

141-5

issue

2

eissn

0263-6484

issn

1099-0844

journal_volume

26

pub_type

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