Abstract:
:We report a functional characterisation of the novel protein MGC13096. MGC13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1), cAMP response element binding protein (CREB), nuclear factor of activated T cells (NFAT), NF-kappaB, signal transducer and activator of transcription 1 (STAT1) took part in the process.
journal_name
Cell Biochem Functjournal_title
Cell biochemistry and functionauthors
Chen Q,Yan C,Yan Q,Feng L,Chen J,Qian Kdoi
10.1002/cbf.1410subject
Has Abstractpub_date
2008-03-01 00:00:00pages
141-5issue
2eissn
0263-6484issn
1099-0844journal_volume
26pub_type
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