Proton NMR study of the state of water in fibrin gels, plasma, and blood clots.

abstract：:MRI using hyperpolarized (13) C-labeled pyruvate is a promising tool to biochemically profile tumors and monitor their response to therapy. This technique requires injection of pyruvate into tumor-bearing animals. Pyruvate is an endogenous entity but the influence of exogenously injected bolus doses of pyruvate on tum...

journal_title：Magnetic resonance in medicine

authors： Saito K,Matsumoto S,Devasahayam N,Subramanian S,Munasinghe JP,Morris HD,Lizak MJ,Ardenkjaer-Larsen JH,Mitchell JB,Krishna MC

更新日期：2012-03-01 00:00:00

abstract：:We present new diffusion phantoms dedicated to the study and validation of high-angular-resolution diffusion imaging (HARDI) models. The phantom design permits the application of imaging parameters that are typically employed in studies of the human brain. The phantoms were made of small-diameter acrylic fibers, chose...

journal_title：Magnetic resonance in medicine

authors： Poupon C,Rieul B,Kezele I,Perrin M,Poupon F,Mangin JF

更新日期：2008-12-01 00:00:00

abstract：:The design of a piezoelectric-controlled trimmer capacitor and its use as a tuning element of an MRI surface coil at 63.8 MHz are described. It is found that image quality does not depend strongly on match of the coil to the transmission line but that tuning can be a significant factor. The work is intended to lead ev...

journal_title：Magnetic resonance in medicine

authors： Hyde JS,Rilling RJ,Jesmanowicz A,Kneeland JB

更新日期：1989-10-01 00:00:00

abstract：:T2-weighted MRI of edema in acute myocardial infarction (MI) provides a means of differentiating acute and chronic MI, and assessing the area at risk of infarction. Conventional T2-weighted imaging of edema uses a turbo spin-echo (TSE) readout with dark-blood preparation. Clinical applications of dark-blood TSE method...

journal_title：Magnetic resonance in medicine

authors： Kellman P,Aletras AH,Mancini C,McVeigh ER,Arai AE

更新日期：2007-05-01 00:00:00

abstract：:A simple and reliable method for quantifying the fluid content and characterizing the tissue T2 relaxation properties of animal extremities has been devised. This one-dimensional magnetic resonance imaging experiment, applied to the adjuvant arthritis model in rats, provides a useful, noninvasive monitor of the course...

journal_title：Magnetic resonance in medicine

authors： Borah B,Szeverenyi NM

更新日期：1990-08-01 00:00:00

abstract：:The feasibility of MR subtraction imaging of lung ventilation using air against oxygen using a multiple inversion recovery half-Fourier single-shot turbo spin echo (MIR-HASTE) sequence was investigated. Eight healthy, nonsmoking volunteers (3 males, 5 females; from 27 to 48 years of age) were studied on a 1.5 T MR uni...

journal_title：Magnetic resonance in medicine

authors： Mai VM,Chen Q,Bankier AA,Edelman RR

更新日期：2000-06-01 00:00:00

abstract：:The resolution in conventional BOLD FMRI is considerably lower than can be achieved with other MRI methods, and is insufficient for many important applications. One major difficulty in robustly improving spatial resolution is the poor image quality in BOLD FMRI, which suffers from distortions, blurring, and signal dro...

journal_title：Magnetic resonance in medicine

authors： Miller KL,Smith SM,Jezzard P,Pauly JM

更新日期：2006-01-01 00:00:00

abstract：:When developing new techniques for NMR imaging and in vivo spectroscopy it is a major advantage to be able to calculate the magnetization slice profiles, at any point during a pulse sequence in the presence of a field gradient. While this has frequently been done by treating the problem as a number of discrete resonan...

journal_title：Magnetic resonance in medicine

authors： Bulsing JM,Galloway GJ,Brereton IM,Doddrell DM

更新日期：1987-11-01 00:00:00

abstract：:The signals of water in the different compartments of rat sciatic nerve are resolved in the (2)H double-quantum-filtered NMR spectrum, due to their different quadrupolar splittings and relaxation rates. This resolution allowed the independent measurement of the water diffusion coefficients in the different compartment...

journal_title：Magnetic resonance in medicine

authors： Seo Y,Shinar H,Morita Y,Navon G

更新日期：1999-09-01 00:00:00

abstract：:High-resolution turbo spin echo (TSE) images have demonstrated important details of carotid artery morphology; however, it is evident that pulsatile blood and wall motion related to the cardiac cycle are still significant sources of image degradation. Although ECG gating can reduce artifacts due to cardiac-induced pul...

journal_title：Magnetic resonance in medicine

authors： Mendes J,Parker DL,Hulet J,Treiman GS,Kim SE

更新日期：2011-11-01 00:00:00

abstract：:A method for evaluating the sensitivity of MRI protocols to changes in an arbitrary number of tissue parameters over a broad range of parameter values is presented. This analysis is useful for choosing an optimal basis set of images for either a "survey" protocol or tissue segmentation algorithms. A survey protocol is...

journal_title：Magnetic resonance in medicine

authors： McVeigh ER,Henkelman RM,Bronskill MJ

更新日期：1990-02-01 00:00:00

abstract：:It has been suggested that orientational changes in the collagen network of articular cartilage account for the depthwise T2 anisotropy of MRI through the magic angle effect. To investigate the relationship between laminar T2 appearance and collagen organization (anisotropy), bovine osteochondral plugs (N = 9) were T2...

journal_title：Magnetic resonance in medicine

authors： Nieminen MT,Rieppo J,Töyräs J,Hakumäki JM,Silvennoinen J,Hyttinen MM,Helminen HJ,Jurvelin JS

更新日期：2001-09-01 00:00:00

abstract：:Strong, extensive magnetic fringe fields are a significant problem with magnetic resonance imaging magnets. This is particularly acute with 4-T, whole-body research magnets. To date this problem has been addressed by restricting an extensive zone around the unshielded magnet or by placing external unsaturated iron shi...

journal_title：Magnetic resonance in medicine

authors： Huson FR,Bryan RN,MacKay WW,Herrick RC,Colvin J,Ford JJ,Pissanetzky S,Plishker GA,Rocha R,Schmidt W

更新日期：1993-01-01 00:00:00

abstract：:Due to a delayed echo-formation, echo-shifted gradient echo sequences (ES-GRE) allow for an enhanced T(2)*-weighting at short repetition times. While they are in use with and without RF spoiling, analytical solutions are only known for the latter. The signal formation in the former could only be assessed in approximat...

journal_title：Magnetic resonance in medicine

authors： Ganter C

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To investigate Shift Undersampling improves Parametric mapping Efficiency and Resolution (SUPER), a novel blockwise curve-fitting method for accelerating parametric mapping with very fast reconstruction. METHODS:SUPER uses interleaved k-space undersampling, which enables a blockwise decomposition of the otherw...

journal_title：Magnetic resonance in medicine

authors： Hu C,Peters DC

更新日期：2019-06-01 00:00:00

abstract：:Imaging of stable paramagnetic spin probes in phantom objects and in vivo was evaluated using a RF time domain EPR spectrometer/imager operating at 300 MHz. Projections were collected using static magnetic field gradients and images were reconstructed using filtered back-projection techniques. Results from phantom obj...

journal_title：Magnetic resonance in medicine

authors： Afeworki M,van Dam GM,Devasahayam N,Murugesan R,Cook J,Coffin D,Larsen JH,Mitchell JB,Subramanian S,Krishna MC

更新日期：2000-03-01 00:00:00

abstract：:The estrogen receptor (ER) is a major prognostic biomarker of breast cancer, currently determined in surgical specimens by immunohistochemistry. Two new ER-targeted probes, pyridine-tetra-acetate-Gd chelate (PTA-Gd) conjugated either to 17β-estradiol (EPTA-Gd) or to tamoxifen (TPTA-Gd), were explored as contrast agent...

journal_title：Magnetic resonance in medicine

authors： Pais A,Biton IE,Margalit R,Degani H

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:For the application of compressive sensing to parallel MRI, Poisson disk sampling (PDS) has been shown to generate superior results compared with random sampling methods. However, due to its limited flexibility to incorporate additional constraints, PDS is not readily extendible to dynamic applications. Here, w...

journal_title：Magnetic resonance in medicine

authors： Ahmad R,Xue H,Giri S,Ding Y,Craft J,Simonetti OP

更新日期：2015-11-01 00:00:00

abstract：:Skeletal muscle triglycerides are markers for insulin resistance in type 2 diabetes. Recently, MR spectroscopy was adapted for in vivo measurement of triglycerides in animal models and for the characterization of new therapeutic approaches. Because of small MR spectroscopy voxel sizes used in skeletal muscles, surface...

journal_title：Magnetic resonance in medicine

authors： Neumaier M,Niessen HG,Kaulisch T,Stiller D

更新日期：2009-10-01 00:00:00

abstract：:Orientational anisotropy of T2 and T1 relaxation times, diffusion, and magnetization transfer has been investigated for six different tissues: tendon, cartilage, kidney, muscle, white matter, and optic nerve. Relaxation anisotropy was observed for tendon and cartilage, and diffusional anisotropy was measured in kidney...

journal_title：Magnetic resonance in medicine

authors： Henkelman RM,Stanisz GJ,Kim JK,Bronskill MJ

更新日期：1994-11-01 00:00:00

abstract：:A new decoupling sequence, PBAR, is described for broadband heteronuclear decoupling in vivo in humans at 1.5T. The sequence uses non-adiabatic, frequency- and amplitude-modulated inversion pulses designed to minimize decoupling sidebands at low applied gammaB(2) RF field levels and to cover only the narrow range of r...

journal_title：Magnetic resonance in medicine

authors： Barker PB,Golay X,Artemov D,Ouwerkerk R,Smith MA,Shaka AJ

更新日期：2001-02-01 00:00:00

abstract：PURPOSE:To investigate the influence of transcytolemmal water exchange on estimates of tissue microstructural parameters derived from diffusion MRI using conventional PGSE and IMPULSED methods. METHODS:Computer simulations were performed to incorporate a broad range of intracellular water life times τin (50-∞ ms), cel...

journal_title：Magnetic resonance in medicine

authors： Li H,Jiang X,Xie J,Gore JC,Xu J

更新日期：2017-06-01 00:00:00

abstract：:Using a 32-echo imaging pulse sequence, T2 relaxation decay curves were acquired from five white- and six gray-matter brain structures outlined in 12 normal volunteers. The water contents of white and gray matter were 0.71 (0.01) and 0.83 (0.03) g/ml, respectively. All white-matter structures had significantly higher ...

journal_title：Magnetic resonance in medicine

authors： Whittall KP,MacKay AL,Graeb DA,Nugent RA,Li DK,Paty DW

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:The goal of this work was to detect disease-related microstructural changes to the liver using magnetic resonance imaging. Chronic liver disease can cause microstructural changes in the liver that reduce plasma access to the perisinusoidal space--the site of exchange between the blood plasma and the hepatic par...

journal_title：Magnetic resonance in medicine

authors： Beeman SC,Mandarino LJ,Georges JF,Bennett KM

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Multiple nonlinear gradient fields offer many potential benefits for spatial encoding including reduced acquisition time, fewer artefacts and region-specific imaging, although designing a suitable trajectory for such a setup is difficult. This work aims to optimize encoding trajectories for multiple nonlinear g...

journal_title：Magnetic resonance in medicine

authors： Layton KJ,Kroboth S,Jia F,Littin S,Yu H,Zaitsev M

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:To characterize the fundamental limits of MRI near metallic implants on RF excitation, frequency encoding, and chemical shift-encoding water-fat separation. METHODS:Multicomponent three-dimensional (3D) digital models of a total hip and a total knee replacement were used to construct material-specific suscepti...

journal_title：Magnetic resonance in medicine

authors： Smith MR,Artz NS,Wiens C,Hernando D,Reeder SB

更新日期：2015-12-01 00:00:00

abstract：:MR techniques have proven their ability to investigate skeletal muscle function in situ. Their benefit in terms of noninvasiveness is, however, lost in animal research, given that muscle stimulation and force output measurements are usually achieved using invasive surgical procedures, thereby excluding repeated invest...

journal_title：Magnetic resonance in medicine

authors： Giannesini B,Vilmen C,Le Fur Y,Dalmasso C,Cozzone PJ,Bendahan D

更新日期：2010-07-01 00:00:00

abstract：:Volume-localized proton NMR spectroscopy was used to estimate bone marrow cellularity in the posterior iliac crests of patients undergoing treatment with hematopoietic growth factors for a variety of hematologic and neoplastic disorders. Twelve patients were accrued, six of whom were studied more than once, yielding a...

journal_title：Magnetic resonance in medicine

authors： Ballon D,Jakubowski A,Gabrilove J,Graham MC,Zakowski M,Sheridan C,Koutcher JA

更新日期：1991-05-01 00:00:00

abstract：:We have demonstrated that echo-planar imaging can be used to produce high-quality snapshot images of the human fetus in utero in a fraction of a second. These images are free of motional artifact or blurring and allow detailed depiction of fetal structures in normal and pathological pregnancies. ...

journal_title：Magnetic resonance in medicine

authors： Stehling MK,Mansfield P,Ordidge RJ,Coxon R,Chapman B,Blamire A,Gibbs P,Johnson IR,Symonds EM,Worthington BS

更新日期：1990-02-01 00:00:00

abstract：:Quantitative estimation of T1 is a challenging but important task inherent to many clinical applications. The most commonly used paradigm for estimating T1 in vivo involves performing a sequence of spoiled gradient-recalled echo acquisitions at different flip angles, followed by fitting of an exponential model to the ...

journal_title：Magnetic resonance in medicine

authors： Trzasko JD,Mostardi PM,Riederer SJ,Manduca A

更新日期：2013-06-01 00:00:00