Abstract:
:We analyzed the whole genomes of cecum microbiomes of Ethiopian indigenous chickens from two distinct geographical zones: Afar (AF) district (Dulecha, 730 m above sea level) and Amhara (AM) district (Menz Gera Midir, 3300 m). Through metagenomic analysis we found that microbial populations were mainly dominated by Bacteroidetes and Firmicutes. We identified 2210 common genes in the two groups. LEfSe showed that the distribution of Coprobacter, Geobacter, Cronobacter, Alloprevotella, and Dysgonomonas were more abundant in AF than AM. Analyses using KEGG, eggNOG, and CAZy databases indicated that the pathways of metabolism, genetic information processing, environmental information processing, and cellular process were significantly enriched. Functional abundance was found to be associated with the nutrient absorption and microbial localization of indigenous chickens. We also investigated antibiotic resistant genes and found antibiotics like LSM, cephalosporin, and tetracycline were significantly more abundant in AF than AM.
journal_name
Genomicsjournal_title
Genomicsauthors
Kumar H,Park W,Lim D,Srikanth K,Kim JM,Jia XZ,Han JL,Hanotte O,Park JE,Oyola SOdoi
10.1016/j.ygeno.2019.11.011subject
Has Abstractpub_date
2020-03-01 00:00:00pages
1988-1999issue
2eissn
0888-7543issn
1089-8646pii
S0888-7543(19)30577-4journal_volume
112pub_type
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