Abstract:
:We have constructed a genetic linkage map of 17 markers on the long arm of human chromosome 21, including six genes and two anonymous loci with a variable number of tandem repeats. The estimated length of the map is 103 cM in males and 140 cM in females, assuming Kosambi interference. Recombination in females was approximately twice that in males between proximal markers. However, over half of the recombination events in either sex occur distally, in 21q22.3, although this region accounts for only about 15% of the physical length of chromosome 21.
journal_name
Genomicsjournal_title
Genomicsauthors
Warren AC,Slaugenhaupt SA,Lewis JG,Chakravarti A,Antonarakis SEdoi
10.1016/0888-7543(89)90282-6subject
Has Abstractpub_date
1989-05-01 00:00:00pages
579-91issue
4eissn
0888-7543issn
1089-8646journal_volume
4pub_type
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