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Mapping of human chromosome 5 microsatellite DNA polymorphisms.

Abstract：

:Thirteen moderately to highly informative microsatellite DNA polymorphisms based on (dC-dA)n.(dG-dT)n repeats were mapped to segments of human chromosome 5 using both linkage analysis and a panel of somatic cell hybrids which contained rearranged chromosomes. The markers were distributed throughout most of the length of the chromosome from the regions p15.3-p15.1 to q33.3-qter. Maps of the sites of meiotic recombination within the reference families proved particularly useful for the purpose of integrating new polymorphisms into the existing linkage map.

journal_name

Genomics

journal_title

Genomics

authors

Weber JL,Polymeropoulos MH,May PE,Kwitek AE,Xiao H,McPherson JD,Wasmuth JJ

doi

10.1016/0888-7543(91)90077-r

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

695-700

issue

3

eissn

0888-7543

issn

1089-8646

pii

0888-7543(91)90077-R

journal_volume

11

pub_type

杂志文章

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