Abstract:
:The human homeobox-containing genes EN1 and EN2 are closely related to the Drosophila pattern formation gene engrailed (en), which may be important in brain development, as shown by gene expression studies during mouse embryogenesis. Here, we have refined the localization of EN1 to human chromosome 2q13-q21 using a mapping panel of rodent/human cell hybrids containing different regions of chromosome 2 and a lymphoblastoid cell line with an interstitial deletion, del(2)(q21-q23.2). This regional assignment of EN1 increases to 22 the number of currently known genes on human chromosome 2q that have homologs on the proximal region of mouse chromosome 1.
journal_name
Genomicsjournal_title
Genomicsauthors
Köhler A,Logan C,Joyner AL,Muenke Mdoi
10.1006/geno.1993.1045subject
Has Abstractpub_date
1993-01-01 00:00:00pages
233-5issue
1eissn
0888-7543issn
1089-8646pii
S0888-7543(83)71045-1journal_volume
15pub_type
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