Abstract:
:We have used probes from the human genes PI, PIL, and AACT (alpha 1-antitrypsin, alpha 1-antitrypsin-related sequence, and alpha 1-antichymotrypsin) to make a pulsed-field map of the surrounding region of 14q31-32. We have discovered that the PI-PIL gene cluster is only 220 kb away from the AACT gene and that it is orientated in the opposite direction. The comparatively short distance between the genes comes as a surprise given previous estimates of the level of genetic recombination between them.
journal_name
Genomicsjournal_title
Genomicsauthors
Sefton L,Kelsey G,Kearney P,Povey S,Wolfe Jdoi
10.1016/0888-7543(90)90172-qsubject
Has Abstractpub_date
1990-07-01 00:00:00pages
382-8issue
3eissn
0888-7543issn
1089-8646pii
0888-7543(90)90172-Qjournal_volume
7pub_type
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