Abstract:
:A cDNA clone encoding the major antigen (CDR62) associated with the antibody-induced paraneoplastic cerebellar degeneration has been used to identify the chromosomal location of the corresponding structural gene(s) by screening for its retention in a panel of rodent-human somatic cell hybrids. Having established the synteny of the gene with the autosome 16, we proceeded to its precise subregional mapping by in situ fluorescence hybridization with a recombinant lambda phage containing the genomic region homologous to the cDNA gene. The latter studies pin-pointed the chromosomal localization of the structural CDR62 gene within the interval 16p12-16p13.1.
journal_name
Genomicsjournal_title
Genomicsauthors
Gress T,Baldini A,Rocchi M,Furneaux H,Posner JB,Siniscalco Mdoi
10.1016/0888-7543(92)90063-xsubject
Has Abstractpub_date
1992-08-01 00:00:00pages
1340-2issue
4eissn
0888-7543issn
1089-8646journal_volume
13pub_type
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