Abstract:
:In our previous studies, diploid and triploid hybrids have been detected from the hybridization of Epinephelus coioides♀ × E. lanceolatus♂. The triploid groupers have been found to be delayed in gonadal development, but the mechanism remains poorly understood. In this study, we examined the gonadal development, assayed the serum steroid hormone levels, and compared the BP (brain and pituitary) and G (gonad) transcriptomes of 18-month-old diploid and triploid hybrids. The results showed that levels of serum estradiol-17β and testosterone were significantly higher in triploid groupers. The RNA-seq data revealed that 1518 and 14,963 differentially expressed genes were identified in the BP and G transcriptome, respectively. Further analysis revealed that the expression levels of genes involved in the sexual differentiation pathway and sex steroid synthesis pathway are significantly higher in triploid hybrids. Our findings provided a comprehensive insight into a better understanding of the regulatory mechanisms of sterility in triploid hybrid fish.
journal_name
Genomicsjournal_title
Genomicsauthors
Xiao L,Wang D,Guo Y,Tang Z,Liu Q,Li S,Zhang Y,Lin Hdoi
10.1016/j.ygeno.2018.11.010subject
Has Abstractpub_date
2019-05-01 00:00:00pages
251-259issue
3eissn
0888-7543issn
1089-8646pii
S0888-7543(18)30052-1journal_volume
111pub_type
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