Abstract:
:This work describes a novel method, multiplex solid-phase fluorescent minisequencing, for the simultaneous detection of several point mutations and/or small deletions and insertions. The method is applied to the analysis of mitochondrial DNA polymorphisms for the purposes of individual identification. A database of 152 British Caucasians and 103 British Afro-Caribbeans has been constructed, and the probability of a chance match between two unrelated individuals is calculated as 0.054 for Caucasians and 0.026 for Afro-Caribbeans.
journal_name
Genomicsjournal_title
Genomicsauthors
Tully G,Sullivan KM,Nixon P,Stones RE,Gill Pdoi
10.1006/geno.1996.0247subject
Has Abstractpub_date
1996-05-15 00:00:00pages
107-13issue
1eissn
0888-7543issn
1089-8646pii
S0888-7543(96)90247-5journal_volume
34pub_type
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