当前位置： SCI文献检索 > Brain Stimulation期刊下所有文献 > Common and unique responses to dopamine agonist therapy and deep brain stimulation in Parkinson's disease: an H(2)(15)O PET study.

Common and unique responses to dopamine agonist therapy and deep brain stimulation in Parkinson's disease: an H(2)(15)O PET study.

Abstract：

BACKGROUND:Dopamine agonist therapy and deep brain stimulation (DBS) of the subthalamic nucleus (STN) are antiparkinsonian treatments that act on a different part of the basal ganglia-thalamocortical motor circuitry, yet produce similar symptomatic improvements. OBJECTIVE/HYPOTHESIS:The purpose of this study was to identify common and unique brain network features of these standard treatments. METHODS:We analyzed images produced by H(2)(15)O positron emission tomography (PET) of patients with Parkinson's disease (PD) at rest. Nine patients were scanned before and after injection of apomorphine, and 11 patients were scanned while bilateral stimulators were off and while they were on. RESULTS:Both treatments produced common deactivations of the neocortical sensorimotor areas, including the supplementary motor area, precentral gyrus, and postcentral gyrus, and in subcortical structures, including the putamen and cerebellum. We observed concomitant activations of the superior parietal lobule and the midbrain in the region of the substantia nigra/STN. We also detected unique, treatment-specific changes with possible motor-related consequences in the basal ganglia, thalamus, neocortical sensorimotor cortex, and posterolateral cerebellum. Unique changes in nonmotor regions may reflect treatment-specific effects on verbal fluency and limbic functions. CONCLUSIONS:Many of the common effects of these treatments are consistent with the standard pathophysiologic model of PD. However, the common effects in the cerebellum are not readily explained by the model. Consistent deactivation of the cerebellum is interesting in light of recent reports of synaptic pathways directly connecting the cerebellum and basal ganglia, and may warrant further consideration for incorporation into the model.

journal_name

Brain Stimul

journal_title

Brain stimulation

authors

Bradberry TJ,Metman LV,Contreras-Vidal JL,van den Munckhof P,Hosey LA,Thompson JL,Schulz GM,Lenz F,Pahwa R,Lyons KE,Braun AR

doi

10.1016/j.brs.2011.09.002

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

605-15

issue

4

eissn

1935-861X

issn

1876-4754

pii

S1935-861X(11)00126-4

journal_volume

5

pub_type

杂志文章

相关文献

Brain Stimulation文献大全
  • Effects of transcutaneous spinal direct current stimulation in idiopathic restless legs patients.

    abstract：BACKGROUND:Transcutaneous spinal direct current stimulation (tsDCS) is a new non-invasive technique to modulate spinal cord activity. The pathophysiological concept of primary RLS proposes increased spinal excitability. OBJECTIVE:This pilot study used tsDCS to reduce pathologically enhanced spinal excitability in RLS ...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2014.06.008

    authors： Heide AC,Winkler T,Helms HJ,Nitsche MA,Trenkwalder C,Paulus W,Bachmann CG

    更新日期：2014-09-01 00:00:00

  • rTMS of the dorsomedial prefrontal cortex for major depression: safety, tolerability, effectiveness, and outcome predictors for 10 Hz versus intermittent theta-burst stimulation.

    abstract：BACKGROUND:Conventional rTMS protocols for major depression commonly employ stimulation sessions lasting >30 min. However, recent studies have sought to improve costs, capacities, and outcomes by employing briefer protocols such as theta burst stimulation (iTBS). OBJECTIVE:To compare safety, effectiveness, and outcome...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2014.11.002

    authors： Bakker N,Shahab S,Giacobbe P,Blumberger DM,Daskalakis ZJ,Kennedy SH,Downar J

    更新日期：2015-03-01 00:00:00

  • Dorsomedial prefrontal cortex repetitive transcranial magnetic stimulation for treatment-refractory major depressive disorder: A three-arm, blinded, randomized controlled trial.

    abstract：BACKGROUND:Dorsomedial prefrontal cortex (DMPFC) repetitive transcranial magnetic stimulation (rTMS) is a novel intervention for treatment-refractory depression (TRD). To date, many open-label case series and one randomized controlled trial of modest sample size have provided preliminary evidence that DMPFC-rTMS is an ...

    journal_title：Brain stimulation

    pub_type： 信件,随机对照试验

    doi：10.1016/j.brs.2019.10.020

    authors： Dunlop K,Sheen J,Schulze L,Fettes P,Mansouri F,Feffer K,Blumberger DM,Daskalakis ZJ,Kennedy SH,Giacobbe P,Woodside B,Downar J

    更新日期：2020-01-01 00:00:00

  • Neuro-Cardiac-Guided TMS (NCG-TMS): Probing DLPFC-sgACC-vagus nerve connectivity using heart rate - First results.

    abstract：BACKGROUND:Given that many studies suggest a role of DLPFC-sgACC connectivity in depression and prior research demonstrating that neuromodulation of either of these nodes modulates parasympathetic activity and results in a heart rate deceleration, a new method is proposed to individualize localization of the DLPFC. Thi...

    journal_title：Brain stimulation

    pub_type： 信件

    doi：10.1016/j.brs.2017.05.002

    authors： Iseger TA,Padberg F,Kenemans JL,Gevirtz R,Arns M

    更新日期：2017-01-01 00:00:00

  • Repetitive transcranial magnetic stimulation-associated neurobehavioral gains during coma recovery.

    abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive method to induce changes in cortical neural excitability. This report presents findings from the first participant of a safety and efficacy study that examined a therapeutic rTMS protocol for persons with severe traumatic brain injury (TBI)...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2008.09.004

    authors： Louise-Bender Pape T,Rosenow J,Lewis G,Ahmed G,Walker M,Guernon A,Roth H,Patil V

    更新日期：2009-01-01 00:00:00

  • Dualistic effect of pallidal deep brain stimulation on motor speech disorders in dystonia.

    abstract：BACKGROUND:Although pallidal deep brain stimulation (GPi-DBS) is an effective treatment for dystonia, it may cause important stimulation-induced side-effects such as hypokinetic dysarthria or stuttering. However, the reasons behind the occurrence of these side-effects remain unknown. OBJECTIVE:To objectively investiga...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2018.03.007

    authors： Rusz J,Tykalová T,Fečíková A,Šťastná D,Urgošík D,Jech R

    更新日期：2018-01-01 00:00:00

  • Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): A proof-of-concept study.

    abstract：OBJECTIVE:To assay peripheral inter-ictal cytokine serum levels and possible relations with non-invasive vagus nerve stimulation (nVNS) responsiveness in migraineurs. METHODS:This double-blinded, sham-controlled study enrolled 48 subjects and measured headache severity, frequency [headache days/month, number of total ...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2019.01.008

    authors： Chaudhry SR,Lendvai IS,Muhammad S,Westhofen P,Kruppenbacher J,Scheef L,Boecker H,Scheele D,Hurlemann R,Kinfe TM

    更新日期：2019-01-01 00:00:00

  • Predictors of deep brain stimulation outcome in tremor patients.

    abstract：BACKGROUND:Deep brain stimulation of the ventro-intermedius nucleus of the thalamus is an established treatment for tremor of differing etiologies but factors that may predict the short- and especially long-term outcome of surgery are still largely unknown. METHODS:We retrospectively investigated the clinical, pharmac...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2017.12.014

    authors： Sandoe C,Krishna V,Basha D,Sammartino F,Tatsch J,Picillo M,di Biase L,Poon YY,Hamani C,Reddy D,Munhoz RP,Lozano AM,Hutchison WD,Fasano A

    更新日期：2018-01-01 00:00:00

  • Novel attempts to optimize vagus nerve stimulation parameters on serotonin neuronal firing activity in the rat brain.

    abstract：BACKGROUND:Vagus nerve stimulation (VNS) is indicated for treatment-resistant epilepsy and depression. Electrophysiologic recordings in the rat brain have shown that VNS promptly increases the firing rate of NE neurons and subsequently that of 5-HT neurons. Thus far, it appears that the standard stimulation parameters ...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2011.04.005

    authors： Manta S,El Mansari M,Blier P

    更新日期：2012-07-01 00:00:00

  • Entrainment of cerebellar purkinje cells with directional AC electric fields in anesthetized rats.

    abstract：BACKGROUND:Transcranial electrical stimulation (tES) shows promise to treat neurological disorders. Knowledge of how the orthogonal components of the electric field (E-field) alter neuronal activity is required for strategic placement of transcranial electrodes. Yet, essentially no information exists on this relationsh...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2020.08.017

    authors： Asan AS,Lang EJ,Sahin M

    更新日期：2020-01-01 00:00:00

  • Cortical inhibitory and excitatory function in drug-naive generalized anxiety disorder.

    abstract：BACKGROUND:A growing body of evidence suggests that deficits in GABAergic inhibitory and glutamatergic excitatory neurotransmission may be involved in the core pathophysiology of generalized anxiety disorder (GAD), a disease characterized by pathological anxious worrying. The aim of the present study was to measure mot...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2016.12.007

    authors： Li CT,Lu CF,Lin HC,Huang YZ,Juan CH,Su TP,Bai YM,Chen MH,Lin WC

    更新日期：2017-01-01 00:00:00

  • Experimental Characterization of the Electric Field Distribution Induced by TMS Devices.

    abstract：BACKGROUND:In transcranial magnetic stimulation (TMS) a strong, brief current pulse driven through a coil is used for non-invasively stimulating the cortex. Properties of the electric field (E-field) induced by the pulse together with physiological parameters determine the outcome of the stimulation. In research and cl...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2015.01.004

    authors： Nieminen JO,Koponen LM,Ilmoniemi RJ

    更新日期：2015-05-01 00:00:00

  • Induction of LTD-like corticospinal plasticity by low-frequency rTMS depends on pre-stimulus phase of sensorimotor μ-rhythm.

    abstract：BACKGROUND:Neural oscillations reflect rapidly changing brain excitability states. We have demonstrated previously with EEG-triggered transcranial magnetic stimulation (TMS) of human motor cortex that the positive vs. negative peak of the sensorimotor μ-oscillation reflect corticospinal low-vs. high-excitability states...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2020.09.005

    authors： Baur D,Galevska D,Hussain S,Cohen LG,Ziemann U,Zrenner C

    更新日期：2020-01-01 00:00:00

  • Temporal plasticity in auditory cortex improves neural discrimination of speech sounds.

    abstract：BACKGROUND:Many individuals with language learning impairments exhibit temporal processing deficits and degraded neural responses to speech sounds. Auditory training can improve both the neural and behavioral deficits, though significant deficits remain. Recent evidence suggests that vagus nerve stimulation (VNS) paire...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2017.01.007

    authors： Engineer CT,Shetake JA,Engineer ND,Vrana WA,Wolf JT,Kilgard MP

    更新日期：2017-01-01 00:00:00

  • The antidepressant-like effect of tDCS in mice: A behavioral and neurobiological characterization.

    abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) is a non-invasive method increasingly popular for the treatment of several brain disorders, such as major depression. Despite great enthusiasm and promising results, some studies report discrepant findings and no consensus exists for the clinical use of tDCS. O...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2017.03.012

    authors： Peanlikhit T,Van Waes V,Pedron S,Risold PY,Haffen E,Etiévant A,Monnin J

    更新日期：2017-01-01 00:00:00

  • External trigeminal nerve stimulation for drug resistant epilepsy: A randomized controlled trial.

    abstract：BACKGROUND:External trigeminal nerve stimulation (ETNS) is an emergent, non-invasive neurostimulation therapy delivered bilaterally with adhesive skin electrodes. In previous studies, ETNS was associated to a decrease in seizure frequency in patients with focal drug-resistant epilepsy (DRE). OBJECTIVE:To determine the...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2020.06.005

    authors： Gil-López F,Boget T,Manzanares I,Donaire A,Conde-Blanco E,Baillés E,Pintor L,Setoaín X,Bargalló N,Navarro J,Casanova J,Valls J,Roldán P,Rumià J,Casanovas G,Domenech G,Torres F,Carreño M

    更新日期：2020-01-01 00:00:00

  • High frequency stimulation of the infralimbic cortex induces morphological changes in rat hippocampal neurons.

    abstract：BACKGROUND:Although a significant subset of patients with major depressive disorder (MDD) fail to respond to medical or behavioural therapy, deep brain stimulation (DBS) applied to the subgenual cingulate cortex (SCC; sg25) has been shown to reduce depressive symptoms in a subset of patients. This area receives project...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2016.11.013

    authors： Bezchlibnyk YB,Stone SSD,Hamani C,Lozano AM

    更新日期：2017-01-01 00:00:00

  • The Impact of Accelerated HF-rTMS on the Subgenual Anterior Cingulate Cortex in Refractory Unipolar Major Depression: Insights From 18FDG PET Brain Imaging.

    abstract：BACKGROUND:Although one of the most frequent diagnosed mental illnesses worldwide, it appears to be challenging to successfully treat major depressive disorder (MDD). Although the phenomenon of treatment-resistant depression (TRD) still remains unclear, the subgenual anterior cingulate cortex (sgACC) has been put forwa...

    journal_title：Brain stimulation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.brs.2015.01.415

    authors： Baeken C,Marinazzo D,Everaert H,Wu GR,Van Hove C,Audenaert K,Goethals I,De Vos F,Peremans K,De Raedt R

    更新日期：2015-07-01 00:00:00

  • Brain stimulation and inhibitory control.

    abstract：:Inhibitory control mechanisms are important in a range of behaviours to prevent execution of motor acts which, having been planned, are no longer necessary or appropriate. Examples of this can be seen in a range of sports, such as cricket and baseball, where the choice between execution and inhibition of a bat swing m...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2012.03.012

    authors： Juan CH,Muggleton NG

    更新日期：2012-04-01 00:00:00

  • Targeting the parahippocampal area by auditory cortex stimulation in tinnitus.

    abstract：BACKGROUND:The final common pathway in tinnitus generation is considered to be synchronized auditory oscillatory hyperactivity. Intracranial auditory cortex stimulation (iACS) via implanted electrodes has been developed to treat severe cases of intractable tinnitus targeting this final common pathway, in the hope of be...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2014.04.004

    authors： De Ridder D,Vanneste S

    更新日期：2014-09-01 00:00:00

  • Disentangling EEG responses to TMS due to cortical and peripheral activations.

    abstract：BACKGROUND:the use of combined transcranial magnetic stimulation (TMS) and electroencephalography (EEG) for the functional evaluation of the cerebral cortex in health and disease is becoming increasingly common. However, there is still some ambiguity regarding the extent to which brain responses to auditory and somatos...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2020.10.011

    authors： Rocchi L,Di Santo A,Brown K,Ibáñez J,Casula E,Rawji V,Di Lazzaro V,Koch G,Rothwell J

    更新日期：2021-01-01 00:00:00

  • Electrical low frequency stimulation of the kindling site preserves the electrophysiological properties of the rat hippocampal CA1 pyramidal neurons from the destructive effects of amygdala kindling: the basis for a possible promising epilepsy therapy.

    abstract：BACKGROUND:Deep brain stimulation (DBS) has emerged as a potential therapeutic strategy in the treatment of neurological disorders including epilepsy. However, the cellular mechanism responsible for the effects of DBS remains largely undefined. Therefore, using electrophysiological approach, we aimed to determine the a...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2012.11.001

    authors： Ghotbedin Z,Janahmadi M,Mirnajafi-Zadeh J,Behzadi G,Semnanian S

    更新日期：2013-07-01 00:00:00

  • Brain-state determines learning improvements after transcranial alternating-current stimulation to frontal cortex.

    abstract：BACKGROUND:Theories of executive control propose that communication between medial frontal cortex (MFC) and lateral prefrontal cortex (lPFC) is critical for learning. 6-Hz phase synchronization may be the mechanism by which neural activity between MFC and lPFC is coordinated into a functional network. Recent evidence s...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2018.02.008

    authors： Nguyen J,Deng Y,Reinhart RMG

    更新日期：2018-01-01 00:00:00

  • Mapping early changes of cortical motor output after subcortical stroke: a transcranial magnetic stimulation study.

    abstract：:After acute stroke several changes in cortical excitability occur involving affected (AH) and unaffected hemisphere (UH) but whether they contribute to motor recovery is still controversial. We performed transcranial magnetic stimulation mapping of several upper limb muscles over the two hemispheres in thirteen patien...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2012.06.003

    authors： Chieffo R,Inuggi A,Straffi L,Coppi E,Gonzalez-Rosa J,Spagnolo F,Poggi A,Comi G,Comola M,Leocani L

    更新日期：2013-05-01 00:00:00

  • Sound comparison of seven TMS coils at matched stimulation strength.

    abstract：BACKGROUND:Accurate data on the sound emitted by transcranial magnetic stimulation (TMS) coils is lacking. METHODS:We recorded the sound waveforms of seven coils with high bandwidth. We estimated the neural stimulation strength by measuring the induced electric field and applying a strength-duration model to account f...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2020.03.004

    authors： Koponen LM,Goetz SM,Tucci DL,Peterchev AV

    更新日期：2020-01-01 00:00:00

  • Deep brain stimulation evoked potentials may relate to clinical benefit in childhood dystonia.

    abstract：BACKGROUND:Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a treatment for severe childhood-onset dystonia. A common challenge for clinicians is determining which contacts of the DBS electrode to stimulate in order to provide maximum future benefit to the patient. OBJECTIVE:To characterize how th...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2014.06.003

    authors： Bhanpuri NH,Bertucco M,Ferman D,Young SJ,Liker MA,Krieger MD,Sanger TD

    更新日期：2014-09-01 00:00:00

  • Electrical stimulation of the vagus nerve dermatome in the external ear is protective in rat cerebral ischemia.

    abstract：BACKGROUND:Although cervical vagus nerve stimulation is effective for reducing infarct volume in rats, it is not feasible for acute human stroke as it requires surgical incision of the neck. We hypothesized that stimulation of the dermatome in the external ear innervated by the vagus nerve (auricular vagus nerve stimul...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2014.09.009

    authors： Ay I,Napadow V,Ay H

    更新日期：2015-01-01 00:00:00

  • Add-on rTMS for the acute treatment of depressive symptoms is probably more effective in adolescents than in adults: Evidence from real-world clinical practice.

    abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) is considered as an effective treatment for adults with major depressive disorder. However, it remains unknown whether rTMS has comparable or better efficacy in adolescents. OBJECTIVE:The current naturalistic study aimed to investigate the efficacy and cli...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2018.09.007

    authors： Zhang T,Zhu J,Xu L,Tang X,Cui H,Wei Y,Wang Y,Hu Q,Qian Z,Liu X,Tang Y,Li C,Wang J

    更新日期：2019-01-01 00:00:00

  • Catecholaminergic modulation of indices of cognitive flexibility: A pharmaco-tDCS study.

    abstract：BACKGROUND:Dopaminergic activity within the dorsolateral prefrontal cortex (dlPFC) has been implicated in the control of cognitive flexibility. Much of the evidence for a causative relationship between cognitive flexibility and dopamine has come from animal studies, whilst human data have largely been correlational. O...

    journal_title：Brain stimulation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.brs.2018.12.001

    authors： Dennison O,Gao J,Lim LW,Stagg CJ,Aquili L

    更新日期：2019-01-01 00:00:00

  • EEG-triggered TMS reveals stronger brain state-dependent modulation of motor evoked potentials at weaker stimulation intensities.

    abstract：BACKGROUND:Corticospinal excitability depends on the current brain state. The recent development of real-time EEG-triggered transcranial magnetic stimulation (EEG-TMS) allows studying this relationship in a causal fashion. Specifically, it has been shown that corticospinal excitability is higher during the scalp surfac...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2018.09.009

    authors： Schaworonkow N,Triesch J,Ziemann U,Zrenner C

    更新日期：2019-01-01 00:00:00