Abstract:
BACKGROUND:The final common pathway in tinnitus generation is considered to be synchronized auditory oscillatory hyperactivity. Intracranial auditory cortex stimulation (iACS) via implanted electrodes has been developed to treat severe cases of intractable tinnitus targeting this final common pathway, in the hope of being a panacea for tinnitus. However, not everybody responds to this treatment. OBJECTIVE:The electrical brain activity and functional connectivity at rest might determine who is going to respond or not to iACS and might shed light on the pathophysiology of auditory phantom sound generation. METHOD:The resting state electrical brain activity of 5 patients who responded and 5 patients who did not respond to auditory cortex implantation are compared using source localized spectral activity (Z-score of log transformed current density) and lagged phase synchronization. RESULTS:sLORETA source localization reveals significant differences between responders vs non-responders for beta3 in left posterior parahippocampal, hippocampal and amygdala area extending into left insula. Gamma band differences exist in the posterior parahippocampal areas and BA10. Functional connectivity between the auditory cortex and the hippocampal area is increased for beta2, delta and theta2 in responders, as well as between the parahippocampal area and auditory cortex for beta3. CONCLUSION:The resting state functional connectivity and activity between the auditory cortex and parahippocampus might determine whether a tinnitus patient will respond to a cortical implant. The auditory cortex may only be a functional entrance into a larger parahippocampal based tinnitus network.
journal_name
Brain Stimuljournal_title
Brain stimulationauthors
De Ridder D,Vanneste Sdoi
10.1016/j.brs.2014.04.004subject
Has Abstractpub_date
2014-09-01 00:00:00pages
709-17issue
5eissn
1935-861Xissn
1876-4754pii
S1935-861X(14)00163-6journal_volume
7pub_type
杂志文章abstract:OBJECTIVE:To examine the effects of transcranial direct current stimulation (tDCS) on objective and subjective indexes of exercise performance. DESIGN:Systematic review and meta-analysis. DATA SOURCES:A systematic literature search of electronic databases (PubMed, Web of Science, Scopus, Google Scholar) and reference...
journal_title:Brain stimulation
pub_type: 杂志文章,meta分析
doi:10.1016/j.brs.2018.12.002
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Cognitive dysfunction is commonly observed in diabetic patients. We have previously reported that anodal transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex can facilitate visuospatial working memory in diabetic patients with concomitant diabetic peripheral neuropathy and m...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2017.08.007
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:External trigeminal nerve stimulation (ETNS) is an emergent, non-invasive neurostimulation therapy delivered bilaterally with adhesive skin electrodes. In previous studies, ETNS was associated to a decrease in seizure frequency in patients with focal drug-resistant epilepsy (DRE). OBJECTIVE:To determine the...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2020.06.005
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Accurate data on the sound emitted by transcranial magnetic stimulation (TMS) coils is lacking. METHODS:We recorded the sound waveforms of seven coils with high bandwidth. We estimated the neural stimulation strength by measuring the induced electric field and applying a strength-duration model to account f...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2020.03.004
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Electroconvulsive therapy (ECT) is the most effective treatment option for major depressive disorder, so understanding whether its clinical effect relates to structural brain changes is vital for current and future antidepressant research. OBJECTIVE:To determine whether clinical response to ECT is related t...
journal_title:Brain stimulation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.brs.2020.02.020
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has shown significant efficiency in the treatment of several psychiatric disorders. In depressive disorders, the dorsolateral prefrontal cortex (DLPFC) is the main target for rTMS, but the effects of this stimulation on cognitive functions and their neural ...
journal_title:Brain stimulation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brs.2012.10.009
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Non-invasive direct current stimulation (DCS) of the brain induces functional plasticity in vitro and facilitates motor learning across species. The effect of DCS on structural synaptic plasticity is currently unknown. OBJECTIVE:This study addresses the effects and the underlying mechanisms of anodal DCS on...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2019.07.026
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:A prime objective driving the recent development of human neural prosthetics is to stimulate neural circuits in a manner time-locked to ongoing brain activity. The human supplementary motor area (SMA) is a particularly useful target for this objective because it displays characteristic neural activity just p...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2018.03.003
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a treatment for severe childhood-onset dystonia. A common challenge for clinicians is determining which contacts of the DBS electrode to stimulate in order to provide maximum future benefit to the patient. OBJECTIVE:To characterize how th...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2014.06.003
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To assay peripheral inter-ictal cytokine serum levels and possible relations with non-invasive vagus nerve stimulation (nVNS) responsiveness in migraineurs. METHODS:This double-blinded, sham-controlled study enrolled 48 subjects and measured headache severity, frequency [headache days/month, number of total ...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2019.01.008
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Burning mouth syndrome (BMS) is a burning oral sensation without any corresponding abnormal findings. In some cases, BMS is refractory to pharmacologic treatments. Repetitive transcranial magnetic stimulation (rTMS) over left prefrontal cortex induces analgesic effect in both acute and chronic pain. However,...
journal_title:Brain stimulation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brs.2015.10.005
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has shown promise as a treatment for refractory auditory hallucinations (AH) in Schizophrenia. Most previous studies have examined the effect of low frequency, left-sided stimulation (LFL) (1 Hz) to the temporoparietal cortex (TPC). Priming stimulation (6 H...
journal_title:Brain stimulation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brs.2011.12.002
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Recently, navigated transcranial magnetic stimulation (nTMS) has been suggested to be useful in preoperative functional localization of motor cortex in patients having tumors close to the somatomotor cortex. Resection of tumors in anatomically predicted eloquent areas without adverse effects have emphasized ...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2012.04.012
更新日期:2013-05-01 00:00:00
abstract::Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become the surgical therapy of choice for medically intractable Parkinson's disease. However, quantitative understanding of the interaction between the electric field generated by DBS and the underlying neural tissue is limited. Recently, computational ...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2010.01.003
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Given that many studies suggest a role of DLPFC-sgACC connectivity in depression and prior research demonstrating that neuromodulation of either of these nodes modulates parasympathetic activity and results in a heart rate deceleration, a new method is proposed to individualize localization of the DLPFC. Thi...
journal_title:Brain stimulation
pub_type: 信件
doi:10.1016/j.brs.2017.05.002
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) is a surgical neuromodulation procedure with a historically wide range of possible therapeutic indications, including movement disorders, neuropsychiatric conditions, and cognitive disorders. Ongoing research in this field is critical to gain further insights into the mechanisms ...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2019.11.008
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:In transcranial magnetic stimulation (TMS) a strong, brief current pulse driven through a coil is used for non-invasively stimulating the cortex. Properties of the electric field (E-field) induced by the pulse together with physiological parameters determine the outcome of the stimulation. In research and cl...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2015.01.004
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:Previous work in the language domain has shown that 10 Hz rTMS of the left or right posterior inferior frontal gyrus (pIFG) in the prefrontal cortex impaired phonological decision-making, arguing for a causal contribution of the bilateral pIFG to phonological processing. However, the neurophysiological cor...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2019.06.021
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Traditional transcranial magnetic stimulation mapping involves systematically delivering stimuli over a predefined grid. The pseudorandom walk method seeks to improve map acquisition times by abandoning the grid in favour of delivering stimuli randomly over a given area. OBJECTIVES:To i) determine the minim...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2018.07.043
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The left dorsal premotor cortex (PMd) plays an important role in movement selection and is abnormally activated in imaging studies in patients with right-sided focal hand dystonia (FHD). OBJECTIVE:The aims of this study were to assess the role of left PMd in patients with FHD and in the genesis of surround ...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2009.03.004
更新日期:2009-10-01 00:00:00
abstract::Deep brain stimulation (DBS) has evolved into a powerful clinical therapy for a range of neurological disorders, but even with impressive clinical growth, DBS technology has been relatively stagnant over its history. However, enhanced collaborations between neural engineers, neuroscientists, physicists, neurologists, ...
journal_title:Brain stimulation
pub_type: 杂志文章,评审
doi:10.1016/j.brs.2014.07.039
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Combined transcranial magnetic stimulation (TMS) and electroencephalography (EEG) can provide insights into how differing cognitive contexts produce different brain states, through TMS-based measures of effective connectivity. For instance, in a recent study, the amplitude of the TMS-evoked response (TMS-ER)...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2013.11.004
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) has emerged as a potential therapeutic strategy in the treatment of neurological disorders including epilepsy. However, the cellular mechanism responsible for the effects of DBS remains largely undefined. Therefore, using electrophysiological approach, we aimed to determine the a...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2012.11.001
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression, but only some individuals respond. Predicting response could reduce patient and clinical burden. Neural activity related to working memory (WM) has been related to mood improvements, so may represent a biomarker for...
journal_title:Brain stimulation
pub_type: 临床试验,杂志文章
doi:10.1016/j.brs.2017.10.015
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Although one of the most frequent diagnosed mental illnesses worldwide, it appears to be challenging to successfully treat major depressive disorder (MDD). Although the phenomenon of treatment-resistant depression (TRD) still remains unclear, the subgenual anterior cingulate cortex (sgACC) has been put forwa...
journal_title:Brain stimulation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brs.2015.01.415
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Temporal resolution of cortical, auditory processing mechanisms is suggested to be linked to peak frequency of neuronal gamma oscillations in auditory cortex areas (individual gamma frequency, IGF): Individuals with higher IGF tend to have better temporal resolution. HYPOTHESIS:Modulating ongoing gamma acti...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2017.10.008
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:A session of motor skill learning is accompanied by transient increases in corticospinal excitability(CSE), which are thought to reflect acute changes in neuronal connectivity associated with improvements in sensorimotor performance. Factors influencing changes in excitability and motor skill with continued ...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2017.11.005
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Transcutaneous vagus nerve stimulation (tVNS) is a new, non-invasive technique being investigated as an intervention for a variety of clinical disorders, including epilepsy and depression. It is thought to exert its therapeutic effect by increasing central norepinephrine (NE) activity, but the evidence suppo...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2018.12.224
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Studies have found that pairing vagus nerve stimulation (VNS) with motor activity accelerates cortical reorganization. This synchronous pairing may enhance motor recovery. OBJECTIVE:To develop and validate a motor-activated auricular vagus nerve stimulation (MAAVNS) system as a potential neurorehabilitation...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2020.02.028
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Neuromodulation therapies are currently being investigated as potential treatments for depression. One of these treatments involves the stimulation of supraorbital branches of the trigeminal nerve. OBJECTIVE:To show that supraorbital stimulation is effective in preclinical models. METHODS:Rats were given s...
journal_title:Brain stimulation
pub_type: 杂志文章
doi:10.1016/j.brs.2013.11.002
更新日期:2014-03-01 00:00:00