当前位置： SCI文献检索 > Brain Stimulation期刊下所有文献 > EEG-triggered TMS reveals stronger brain state-dependent modulation of motor evoked potentials at weaker stimulation intensities.

EEG-triggered TMS reveals stronger brain state-dependent modulation of motor evoked potentials at weaker stimulation intensities.

Abstract：

BACKGROUND:Corticospinal excitability depends on the current brain state. The recent development of real-time EEG-triggered transcranial magnetic stimulation (EEG-TMS) allows studying this relationship in a causal fashion. Specifically, it has been shown that corticospinal excitability is higher during the scalp surface negative EEG peak compared to the positive peak of μ-oscillations in sensorimotor cortex, as indexed by larger motor evoked potentials (MEPs) for fixed stimulation intensity. OBJECTIVE:We further characterize the effect of μ-rhythm phase on the MEP input-output (IO) curve by measuring the degree of excitability modulation across a range of stimulation intensities. We furthermore seek to optimize stimulation parameters to enable discrimination of functionally relevant EEG-defined brain states. METHODS:A real-time EEG-TMS system was used to trigger MEPs during instantaneous brain-states corresponding to μ-rhythm surface positive and negative peaks with five different stimulation intensities covering an individually calibrated MEP IO curve in 15 healthy participants. RESULTS:MEP amplitude is modulated by μ-phase across a wide range of stimulation intensities, with larger MEPs at the surface negative peak. The largest relative MEP-modulation was observed for weak intensities, the largest absolute MEP-modulation for intermediate intensities. These results indicate a leftward shift of the MEP IO curve during the μ-rhythm negative peak. CONCLUSION:The choice of stimulation intensity influences the observed degree of corticospinal excitability modulation by μ-phase. Lower stimulation intensities enable more efficient differentiation of EEG μ-phase-defined brain states.

journal_name

Brain Stimul

journal_title

Brain stimulation

authors

Schaworonkow N,Triesch J,Ziemann U,Zrenner C

doi

10.1016/j.brs.2018.09.009

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

110-118

issue

1

eissn

1935-861X

issn

1876-4754

pii

S1935-861X(18)30311-5

journal_volume

12

pub_type

杂志文章

相关文献

Brain Stimulation文献大全
  • Structural changes induced by electroconvulsive therapy are associated with clinical outcome.

    abstract：BACKGROUND:Electroconvulsive therapy (ECT) is the most effective treatment option for major depressive disorder, so understanding whether its clinical effect relates to structural brain changes is vital for current and future antidepressant research. OBJECTIVE:To determine whether clinical response to ECT is related t...

    journal_title：Brain stimulation

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.brs.2020.02.020

    authors： Mulders PCR,Llera A,Beckmann CF,Vandenbulcke M,Stek M,Sienaert P,Redlich R,Petrides G,Oudega ML,Oltedal L,Oedegaard KJ,Narr KL,Magnusson PO,Kessler U,Jorgensen A,Espinoza R,Enneking V,Emsell L,Dols A,Dannlowski U,

    更新日期：2020-01-01 00:00:00

  • Alcohol Intoxication by Binge Drinking Impairs Neuroplasticity.

    abstract：BACKGROUND:Binge drinking, resulting in acute alcohol intoxication, is considered an initial step in developing alcohol use disorders (AUDs). It has been suggested that alcohol intoxication may act on mechanisms of neuroplasticity to produce brain changes that contribute to the pathophysiology of AUDs. However, the eff...

    journal_title：Brain stimulation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.brs.2015.08.011

    authors： Loheswaran G,Barr MS,Rajji TK,Blumberger DM,Le Foll B,Daskalakis ZJ

    更新日期：2016-01-01 00:00:00

  • Progressive practice promotes motor learning and repeated transient increases in corticospinal excitability across multiple days.

    abstract：BACKGROUND:A session of motor skill learning is accompanied by transient increases in corticospinal excitability(CSE), which are thought to reflect acute changes in neuronal connectivity associated with improvements in sensorimotor performance. Factors influencing changes in excitability and motor skill with continued ...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2017.11.005

    authors： Christiansen L,Madsen MJ,Bojsen-Møller E,Thomas R,Nielsen JB,Lundbye-Jensen J

    更新日期：2018-01-01 00:00:00

  • After-effects of 10 Hz tACS over the prefrontal cortex on phonological word decisions.

    abstract：INTRODUCTION:Previous work in the language domain has shown that 10 Hz rTMS of the left or right posterior inferior frontal gyrus (pIFG) in the prefrontal cortex impaired phonological decision-making, arguing for a causal contribution of the bilateral pIFG to phonological processing. However, the neurophysiological cor...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2019.06.021

    authors： Moliadze V,Sierau L,Lyzhko E,Stenner T,Werchowski M,Siniatchkin M,Hartwigsen G

    更新日期：2019-01-01 00:00:00

  • The role of inhibition from the left dorsal premotor cortex in right-sided focal hand dystonia.

    abstract：BACKGROUND:The left dorsal premotor cortex (PMd) plays an important role in movement selection and is abnormally activated in imaging studies in patients with right-sided focal hand dystonia (FHD). OBJECTIVE:The aims of this study were to assess the role of left PMd in patients with FHD and in the genesis of surround ...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2009.03.004

    authors： Beck S,Houdayer E,Richardson SP,Hallett M

    更新日期：2009-10-01 00:00:00

  • Functional connectivity of the left DLPFC to striatum predicts treatment response of depression to TMS.

    abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (TMS) is a non-invasive, safe, and efficacious treatment for depression. TMS has been shown to normalize abnormal functional connectivity of cortico-cortical circuits in depression and baseline functional connectivity of these circuits predicts treatment response....

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2017.07.002

    authors： Avissar M,Powell F,Ilieva I,Respino M,Gunning FM,Liston C,Dubin MJ

    更新日期：2017-01-01 00:00:00

  • Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): A proof-of-concept study.

    abstract：OBJECTIVE:To assay peripheral inter-ictal cytokine serum levels and possible relations with non-invasive vagus nerve stimulation (nVNS) responsiveness in migraineurs. METHODS:This double-blinded, sham-controlled study enrolled 48 subjects and measured headache severity, frequency [headache days/month, number of total ...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2019.01.008

    authors： Chaudhry SR,Lendvai IS,Muhammad S,Westhofen P,Kruppenbacher J,Scheef L,Boecker H,Scheele D,Hurlemann R,Kinfe TM

    更新日期：2019-01-01 00:00:00

  • Effects of Stochastic Vestibular Galvanic Stimulation and LDOPA on Balance and Motor Symptoms in Patients With Parkinson's Disease.

    abstract：BACKGROUND:Balance problems contribute to reduced quality of life in Parkinson's disease (PD) and available treatments are often insufficient for treating axial and postural motor symptoms. OBJECTIVE:To investigate the safety of use and possible effects of stochastic vestibular stimulation (SVS) alone and combined wit...

    journal_title：Brain stimulation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.brs.2014.11.019

    authors： Samoudi G,Jivegård M,Mulavara AP,Bergquist F

    更新日期：2015-05-01 00:00:00

  • Closed-loop intracranial stimulation alters movement timing in humans.

    abstract：BACKGROUND:A prime objective driving the recent development of human neural prosthetics is to stimulate neural circuits in a manner time-locked to ongoing brain activity. The human supplementary motor area (SMA) is a particularly useful target for this objective because it displays characteristic neural activity just p...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2018.03.003

    authors： Moore BD 4th,Aron AR,Tandon N

    更新日期：2018-01-01 00:00:00

  • Effects of transcranial direct current stimulation of the primary sensory cortex on somatosensory perception.

    abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) is able to modify cortical excitability and activity in humans. OBJECTIVE:The aim of the present study was to analyze the effects of tDCS of the primary sensory cortex (SI) on thermal and mechanical perception, assessed by quantitative sensory testing (QST). M...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2010.12.002

    authors： Grundmann L,Rolke R,Nitsche MA,Pavlakovic G,Happe S,Treede RD,Paulus W,Bachmann CG

    更新日期：2011-10-01 00:00:00

  • Effects of chronic abdominal vagal stimulation of small-diameter neurons on brain metabolism and food intake.

    abstract：BACKGROUND:Abdominal bilateral vagal stimulation reduces food intake in animals. However, the classical square wave, mA range current generator is poorly effective to evoke action potentials on A∂ and C neurons that represent the majority of vagal neurons at the abdominal level. OBJECTIVE/HYPOTHESIS:METHODS: The curre...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2017.04.126

    authors： Malbert CH,Bobillier E,Picq C,Divoux JL,Guiraud D,Henry C

    更新日期：2017-01-01 00:00:00

  • Response to deep TMS in depressive patients with previous electroconvulsive treatment.

    abstract：BACKGROUND:The efficacy of transcranial magnetic stimulation (TMS) in the treatment of major depression has already been shown. Novel TMS coils allowing stimulation of deeper brain regions have recently been developed and studied. OBJECTIVE:Our study is aimed at exploring the possible efficacy of deep TMS in patients ...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2009.12.001

    authors： Rosenberg O,Zangen A,Stryjer R,Kotler M,Dannon PN

    更新日期：2010-10-01 00:00:00

  • Interactions Among Learning Stage, Retention, and Primary Motor Cortex Excitability in Motor Skill Learning.

    abstract：BACKGROUND:Previous studies have shown that primary motor cortex (M1) excitability is modulated by motor skill learning and that the M1 plays a crucial role in motor memory. However, the following questions remain: (1) At what stage do changes in M1 excitability occur? (2) Are learning-induced changes in leg M1 excitab...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2015.07.025

    authors： Hirano M,Kubota S,Tanabe S,Koizume Y,Funase K

    更新日期：2015-11-01 00:00:00

  • Hearing safety of long-term treatment with theta burst stimulation.

    abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) for the experimental treatment of tinnitus or auditory hallucinations aims at a modulation of cortical activity in areas of auditory perception and processing. Continuous theta burst stimulation (cTBS) is a patterned rTMS paradigm with lower stimulation int...

    journal_title：Brain stimulation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.brs.2012.10.005

    authors： Schraven SP,Plontke SK,Rahne T,Wasserka B,Plewnia C

    更新日期：2013-07-01 00:00:00

  • Somatosensory-motor cortex interactions measured using dual-site transcranial magnetic stimulation.

    abstract：BACKGROUND:Dual-site transcranial magnetic stimulation (ds-TMS) is a neurophysiological technique to measure functional connectivity between cortical areas. OBJECTIVE/HYPOTHESIS:To date, no study has used ds-TMS to investigate short intra-hemispheric interactions between the somatosensory areas and primary motor corte...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2019.04.009

    authors： Brown MJN,Weissbach A,Pauly MG,Vesia M,Gunraj C,Baarbé J,Münchau A,Bäumer T,Chen R

    更新日期：2019-01-01 00:00:00

  • The efficacy and safety of low frequency repetitive transcranial magnetic stimulation for treatment-resistant depression: the results from a large multicenter French RCT.

    abstract：CONTEXT:The aim of this study was to assess whether the combination of low frequency repetitive transcranial magnetic stimulation (rTMS) and venlafaxine (150-225 mg/day) is effective and safe for treatment-resistant unipolar depression (TRD). METHOD:In a multicenter (18 centers) randomized double blind controlled tria...

    journal_title：Brain stimulation

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.brs.2014.07.040

    authors： Brunelin J,Jalenques I,Trojak B,Attal J,Szekely D,Gay A,Januel D,Haffen E,Schott-Pethelaz AM,Brault C,STEP Group.,Poulet E

    更新日期：2014-11-01 00:00:00

  • The effects of transcranial direct current stimulation on objective and subjective indexes of exercise performance: A systematic review and meta-analysis.

    abstract：OBJECTIVE:To examine the effects of transcranial direct current stimulation (tDCS) on objective and subjective indexes of exercise performance. DESIGN:Systematic review and meta-analysis. DATA SOURCES:A systematic literature search of electronic databases (PubMed, Web of Science, Scopus, Google Scholar) and reference...

    journal_title：Brain stimulation

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.brs.2018.12.002

    authors： Holgado D,Vadillo MA,Sanabria D

    更新日期：2019-01-01 00:00:00

  • Responders to rTMS for depression show increased fronto-midline theta and theta connectivity compared to non-responders.

    abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression, but only some individuals respond. Predicting response could reduce patient and clinical burden. Neural activity related to working memory (WM) has been related to mood improvements, so may represent a biomarker for...

    journal_title：Brain stimulation

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.brs.2017.10.015

    authors： Bailey NW,Hoy KE,Rogasch NC,Thomson RH,McQueen S,Elliot D,Sullivan CM,Fulcher BD,Daskalakis ZJ,Fitzgerald PB

    更新日期：2018-01-01 00:00:00

  • Trait-like differences in underlying oscillatory state predict individual differences in the TMS-evoked response.

    abstract：BACKGROUND:Combined transcranial magnetic stimulation (TMS) and electroencephalography (EEG) can provide insights into how differing cognitive contexts produce different brain states, through TMS-based measures of effective connectivity. For instance, in a recent study, the amplitude of the TMS-evoked response (TMS-ER)...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2013.11.004

    authors： Kundu B,Johnson JS,Postle BR

    更新日期：2014-03-01 00:00:00

  • Add-on rTMS for the acute treatment of depressive symptoms is probably more effective in adolescents than in adults: Evidence from real-world clinical practice.

    abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) is considered as an effective treatment for adults with major depressive disorder. However, it remains unknown whether rTMS has comparable or better efficacy in adolescents. OBJECTIVE:The current naturalistic study aimed to investigate the efficacy and cli...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2018.09.007

    authors： Zhang T,Zhu J,Xu L,Tang X,Cui H,Wei Y,Wang Y,Hu Q,Qian Z,Liu X,Tang Y,Li C,Wang J

    更新日期：2019-01-01 00:00:00

  • A fast and general method to empirically estimate the complexity of brain responses to transcranial and intracranial stimulations.

    abstract：BACKGROUND:The Perturbational Complexity Index (PCI) was recently introduced to assess the capacity of thalamocortical circuits to engage in complex patterns of causal interactions. While showing high accuracy in detecting consciousness in brain-injured patients, PCI depends on elaborate experimental setups and offline...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2019.05.013

    authors： Comolatti R,Pigorini A,Casarotto S,Fecchio M,Faria G,Sarasso S,Rosanova M,Gosseries O,Boly M,Bodart O,Ledoux D,Brichant JF,Nobili L,Laureys S,Tononi G,Massimini M,Casali AG

    更新日期：2019-01-01 00:00:00

  • rTMS of the dorsomedial prefrontal cortex for major depression: safety, tolerability, effectiveness, and outcome predictors for 10 Hz versus intermittent theta-burst stimulation.

    abstract：BACKGROUND:Conventional rTMS protocols for major depression commonly employ stimulation sessions lasting >30 min. However, recent studies have sought to improve costs, capacities, and outcomes by employing briefer protocols such as theta burst stimulation (iTBS). OBJECTIVE:To compare safety, effectiveness, and outcome...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2014.11.002

    authors： Bakker N,Shahab S,Giacobbe P,Blumberger DM,Daskalakis ZJ,Kennedy SH,Downar J

    更新日期：2015-03-01 00:00:00

  • Induction of LTD-like corticospinal plasticity by low-frequency rTMS depends on pre-stimulus phase of sensorimotor μ-rhythm.

    abstract：BACKGROUND:Neural oscillations reflect rapidly changing brain excitability states. We have demonstrated previously with EEG-triggered transcranial magnetic stimulation (TMS) of human motor cortex that the positive vs. negative peak of the sensorimotor μ-oscillation reflect corticospinal low-vs. high-excitability states...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2020.09.005

    authors： Baur D,Galevska D,Hussain S,Cohen LG,Ziemann U,Zrenner C

    更新日期：2020-01-01 00:00:00

  • Deep brain stimulation evoked potentials may relate to clinical benefit in childhood dystonia.

    abstract：BACKGROUND:Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a treatment for severe childhood-onset dystonia. A common challenge for clinicians is determining which contacts of the DBS electrode to stimulate in order to provide maximum future benefit to the patient. OBJECTIVE:To characterize how th...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2014.06.003

    authors： Bhanpuri NH,Bertucco M,Ferman D,Young SJ,Liker MA,Krieger MD,Sanger TD

    更新日期：2014-09-01 00:00:00

  • Publication trends in transcranial magnetic stimulation: a 30-year panorama.

    abstract：BACKGROUND:Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulatory technique that has broad diagnostic and therapeutic potential across a range of neurological and psychiatric diseases. OBJECTIVE:This study utilises a bibliometric approach to systematically and comprehensively evaluate the literature...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2019.01.002

    authors： Lawson McLean A

    更新日期：2019-01-01 00:00:00

  • Neuro-Cardiac-Guided TMS (NCG-TMS): Probing DLPFC-sgACC-vagus nerve connectivity using heart rate - First results.

    abstract：BACKGROUND:Given that many studies suggest a role of DLPFC-sgACC connectivity in depression and prior research demonstrating that neuromodulation of either of these nodes modulates parasympathetic activity and results in a heart rate deceleration, a new method is proposed to individualize localization of the DLPFC. Thi...

    journal_title：Brain stimulation

    pub_type： 信件

    doi：10.1016/j.brs.2017.05.002

    authors： Iseger TA,Padberg F,Kenemans JL,Gevirtz R,Arns M

    更新日期：2017-01-01 00:00:00

  • The Efficacy of Daily Prefrontal Repetitive Transcranial Magnetic Stimulation (rTMS) for Burning Mouth Syndrome (BMS): A Randomized Controlled Single-blind Study.

    abstract：BACKGROUND:Burning mouth syndrome (BMS) is a burning oral sensation without any corresponding abnormal findings. In some cases, BMS is refractory to pharmacologic treatments. Repetitive transcranial magnetic stimulation (rTMS) over left prefrontal cortex induces analgesic effect in both acute and chronic pain. However,...

    journal_title：Brain stimulation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.brs.2015.10.005

    authors： Umezaki Y,Badran BW,DeVries WH,Moss J,Gonzales T,George MS

    更新日期：2016-03-01 00:00:00

  • Modulation of Hippocampal Activity by Vagus Nerve Stimulation in Freely Moving Rats.

    abstract：BACKGROUND:Vagus Nerve Stimulation (VNS) has seizure-suppressing effects but the underlying mechanism is not fully understood. To further elucidate the mechanisms underlying VNS-induced seizure suppression at a neurophysiological level, the present study examined effects of VNS on hippocampal excitability using dentate...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2015.09.009

    authors： Larsen LE,Wadman WJ,van Mierlo P,Delbeke J,Grimonprez A,Van Nieuwenhuyse B,Portelli J,Boon P,Vonck K,Raedt R

    更新日期：2016-01-01 00:00:00

  • The Effect of Transcranial Direct Current Stimulation (tDCS) Electrode Size and Current Intensity on Motor Cortical Excitability: Evidence From Single and Repeated Sessions.

    abstract：BACKGROUND:Current density is considered an important factor in determining the outcomes of tDCS, and is determined by the current intensity and electrode size. Previous studies examining the effect of these parameters on motor cortical excitability with small sample sizes reported mixed results. OBJECTIVE/HYPOTHESIS:...

    journal_title：Brain stimulation

    pub_type： 杂志文章

    doi：10.1016/j.brs.2015.08.003

    authors： Ho KA,Taylor JL,Chew T,Gálvez V,Alonzo A,Bai S,Dokos S,Loo CK

    更新日期：2016-01-01 00:00:00

  • A new device to improve target localization for transcranial magnetic stimulation therapy.

    abstract：BACKGROUND:Accurate identification of cranial midline structures is essential for many targeting techniques that use repetitive transcranial magnetic stimulation (rTMS), including the Beam F3 method used for depression treatment. OBJECTIVE:Evaluate whether a novel, laser-sighted device will assist with more accurate i...

    journal_title：Brain stimulation

    pub_type： 信件

    doi：10.1016/j.brs.2019.07.028

    authors： Trapp NT,Uitermarkt B,King Johnson M,Koscik TR,Garrett L,Heinzerling A,Zanaty M,Holland MT,Howard M,Boes AD

    更新日期：2019-01-01 00:00:00