Abstract：
:A new tetramic acid glycoside, aurantoside K, was isolated from a marine sponge belonging to the genus Melophlus. The structure of the compound was elucidated on the basis of spectroscopic analysis (¹H NMR, ¹H-¹H COSY, HSQC, and HMBC, as well as high-resolution ESILCMS). Aurantoside K did not show any significant activity in antimalarial, antibacterial, or HCT-116 cytotoxicity assays, but exhibited a wide spectrum of antifungal activity against wild type Candida albicans, amphotericin-resistant C. albicans, Cryptococcus neoformans, Aspergillus niger, Penicillium sp., Rhizopus sporangia and Sordaria sp.
journal_name
Mar Drugsjournal_title
Marine drugsauthors
Kumar R,Subramani R,Feussner KD,Aalbersberg Wdoi
10.3390/md10010200subject
Has Abstractpub_date
2012-01-01 00:00:00pages
200-8issue
1issn
1660-3397pii
marinedrugs-10-00200journal_volume
10pub_type
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