Abstract：
:Four new xanthene derivatives, penicixanthenes A-D (1-4), and one known compound 5 were isolated from a marine mangrove endophytic fungus Penicillium sp. JY246 that was obtained from the stem of Ceriops tagal. Their structures were determined by detailed NMR, MS spectroscopic data, modified Mosher's method, and calculated electronic circular dichroism data. All of the isolated compounds were examined for insecticidal activity. Compounds 2 and 3 showed growth inhibition activity against newly hatched larvae of Helicoverpa armigera Hubner with the IC50 values 100 and 200 μg/mL, respectively, and compounds 1, 3, and 4 showed insecticidal activity against newly hatched larvae of Culex quinquefasciatus with LC50 values of 38.5 (±1.16), 11.6 (±0.58), and 20.5 (±1) μg/mL, respectively. The four xanthene derivatives have the potential to be developed as new biopesticides.
journal_name
Mar Drugsjournal_title
Marine drugsauthors
Bai M,Zheng CJ,Nong XH,Zhou XM,Luo YP,Chen GYdoi
10.3390/md17120649subject
Has Abstractpub_date
2019-11-20 00:00:00issue
12issn
1660-3397pii
md17120649journal_volume
17pub_type
杂志文章相关文献
Marine Drugs文献大全abstract：:Domoic acid is a marine biotoxin associated with harmful algal blooms and is the causative agent of amnesic shellfish poisoning in marine animals and humans. It is also an excitatory amino acid analog to glutamate and kainic acid which acts through glutamate receptors eliciting a very rapid and potent neurotoxic respo...
journal_title：Marine drugs
pub_type： 杂志文章
doi：
更新日期：2008-02-14 00:00:00
abstract：:Two new compounds-a trioxilin and a sulfoquinovosyl diacylglycerol (SQDG)-were isolated from the methanolic extract of the heterotrophic dinoflagellate Oxyrrhis marina cultivated by feeding on dried yeasts. The trioxilin was identified as (4Z,8E,13Z,16Z,19Z) -7(S),10(S),11(S)-trihydroxydocosapentaenoic acid (1), and t...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md15030057
更新日期：2017-02-27 00:00:00
abstract：:A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md11114585
更新日期：2013-11-14 00:00:00
abstract：:The striking rise of methicillin-resistant Staphylococcus aureus (MRSA) infections has become a serious threat to public health worldwide. In an effort to search for new anti-MRSA agents from natural products, a bioassay-guided phytochemical study was conducted on the semi-mangrove plant Myoporum bontioides A. Gray, w...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md16110438
更新日期：2018-11-08 00:00:00
abstract：:Numerous studies have suggested that hyperlipidemia is closely linked to cardiovascular disease. The aim of this study was to investigate the possible antihyperlipidemia mechanism of HU (high sulfate content of ulvan) in high-cholesterol fed rats. Wistar rats were made hyperlipidemic by feeding with a high-cholesterol...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md13063407
更新日期：2015-05-29 00:00:00
abstract：:Despite the increasing availability of new classes of cancer treatment, such as immune- and targeted therapies, there remains a need for the development of new antiproliferative/cytotoxic drugs with improved pharmacological profiles that can also overcome drug resistant forms of cancer. In this study, we have identifi...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md16020063
更新日期：2018-02-15 00:00:00
abstract：:Six new bis(indole) alkaloids (1-6) along with eight known ones of the topsentin class were isolated from a Spongosorites sp. sponge of Korea. Based on the results of combined spectroscopic analyses, the structures of spongosoritins A-D (1-4) were determined to possess a 2-methoxy-1-imidazole-5-one core connecting the...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md19010003
更新日期：2020-12-23 00:00:00
abstract：:Marine ecosystems are the most prevalent ecosystems on the planet, providing a diversity of living organisms and resources. The development of nanotechnology may provide solutions for utilizing these thousands of potential compounds as marine pharmaceuticals. Here, we designed a liposomal glycol chitosan formulation t...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md17100581
更新日期：2019-10-12 00:00:00
abstract：:In the present study, histone from immature testis of Atlantic salmon was extracted and identified, and its antibacterial activity after enzymolysis was investigated. Histone extracted from Atlantic salmon (Salmo salar) testis using the acid extraction method was successfully identified by LC-MS/MS, and revealed signi...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md18030133
更新日期：2020-02-26 00:00:00
abstract：:Collagen has become a key-molecule in cell culture studies and in the tissue engineering field. Industrially, the principal sources of collagen are calf skin and bones which, however, could be associated to risks of serious disease transmission. In fact, collagen derived from alternative and riskless sources is requir...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md12094912
更新日期：2014-09-24 00:00:00
abstract：:There is an urgent need for novel strategies to fight drug resistance and multi-drug resistance. As an alternative to the classic antibiotic therapy, attenuation of the bacteria virulence affecting their Quorum sensing (QS) system is a promising approach. Quorum sensing (QS) is a genetic regulation system that allows ...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md15030059
更新日期：2017-02-28 00:00:00
abstract：:Pinnatoxins (PnTXs) are emerging neurotoxins that were discovered about 30 years ago. They are solely produced by the marine dinoflagellate Vulcanodinium rugosum, and may be transferred into the food chain, as they have been found in various marine invertebrates, including bivalves. No human intoxication has been repo...
journal_title：Marine drugs
pub_type： 杂志文章,评审
doi：10.3390/md17070425
更新日期：2019-07-20 00:00:00
abstract：:A new compound containing a triene, a tetrahydropyran ring and glycine ester functionalities, restricticin B (1), together with four known compounds (2-5) were obtained from the EtOAc extract of the marine-derived fungus Penicillium janthinellum. The planar structure of 1 was determined by detailed analyses of MS, 1D ...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md18090465
更新日期：2020-09-14 00:00:00
abstract：:Astaxanthin captured peroxynitrite to form nitroastaxanthins. 15-Nitroastaxanthin was a major reaction product of astaxanthin with peroxynitrite. Here, the anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of 15-nitroastaxanthin were investigated. In addition to astaxanthin, 15-nitroastaxanthin s...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md10061391
更新日期：2012-06-01 00:00:00
abstract：:Cone snails produce a distinctive repertoire of venom peptides that are used both as a defense mechanism and also to facilitate the immobilization and digestion of prey. These peptides target a wide variety of voltage- and ligand-gated ion channels, which make them an invaluable resource for studying the properties of...
journal_title：Marine drugs
pub_type： 杂志文章,评审
doi：10.3390/md10061244
更新日期：2012-06-01 00:00:00
abstract：:The development and use of topical microbicides potentially offers an additional strategy to reduce the spread of the Human Immunodeficiency Virus (HIV). Carbohydrate-binding agents (CBAs) that show specificity for high mannose carbohydrates on the surface of the heavily glycosylated envelope of HIV are endowed with p...
journal_title：Marine drugs
pub_type： 杂志文章,评审
doi：10.3390/md10071476
更新日期：2012-07-01 00:00:00
abstract：:In this review, we focus on processes, organs and systems targeted by the marine toxins yessotoxin (YTX), okadaic acid (OA) and palytoxin (PTX). The effects of YTX and their basis are analyzed from data collected in the mollusc Mytilus galloprovincialis, the annelid Enchytraeus crypticus, Swiss CD1 mice and invertebra...
journal_title：Marine drugs
pub_type： 杂志文章,评审
doi：10.3390/md8030658
更新日期：2010-03-16 00:00:00
abstract：:Hepatic fibrosis is an effusive wound healing process, characterized by an excessive deposition of extracellular matrix (ECM), as the consequence of chronic liver injury of any etiology. Current therapeutic repertoire for hepatic fibrosis is limited to withdrawal of the noxious agent, which is not always feasible. Hen...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md13085201
更新日期：2015-08-18 00:00:00
abstract：:Mycosporine-like amino acids (MAAs) have gained considerable attention as highly active photoprotective candidates for human sunscreens. However, more studies are necessary to evaluate the extraction efficiency of these metabolites in solvents compatible with cosmetics and their subsequent analysis by HPLC. In the pre...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md18010027
更新日期：2019-12-28 00:00:00
abstract：:Ten new cembrane-based diterpenes, locrassumins A-G (1-7), (-)-laevigatol B (8), (-)-isosarcophine (9), and (-)-7R,8S-dihydroxydeepoxysarcophytoxide (10), were isolated from a South China Sea collection of the soft coral Lobophytum crassum, together with eight known analogues (11-18). The structures of the new compoun...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md14060111
更新日期：2016-06-03 00:00:00
abstract：:Sargassum horneri (S. horneri), an edible brown alga, has been proposed as a functional food with an improvement effect on abnormal skin immune responses. The present study investigates the anti-allergic effect of an ethanol extract from S. horneri (SHE) on immunoglobulin E (IgE)/bovine serum albumin (BSA)-mediated ac...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md18120594
更新日期：2020-11-26 00:00:00
abstract：:A marine-derived strain of Clonostachys rosea isolated from sediments of the river Loire estuary (France) was investigated for its high lipid production. The fungal strain was grown on six different culture media to explore lipid production changes. An original branched conjugated fatty acid, mainly present in triglyc...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md13084934
更新日期：2015-08-06 00:00:00
abstract：:The potential of marine natural products to become new drugs is vast; however, research is still in its infancy. The chemical and biological diversity of marine toxins is immeasurable and as such an extraordinary resource for the discovery of new drugs. With the rapid development of next-generation sequencing (NGS) an...
journal_title：Marine drugs
pub_type： 杂志文章,评审
doi：10.3390/md15040103
更新日期：2017-03-30 00:00:00
abstract：:Sea cucumbers have been valued for many centuries as a tonic and functional food, dietary delicacies and important ingredients of traditional medicine in many Asian countries. An assortment of bioactive compounds has been described in sea cucumbers. The most important and abundant secondary metabolites from sea cucumb...
journal_title：Marine drugs
pub_type： 杂志文章,评审
doi：10.3390/md14080147
更新日期：2016-08-04 00:00:00
abstract：:The marine alga, Symphyocladia latiuscula (Harvey) Yamada, is a good source of bromophenols with numerous biological activities. This study aims to characterize the anti-diabetic potential of 2,3,6-tribromo-4,5-dihydroxybenzyl derivatives isolated from S. latiuscula via their inhibition of tyrosine phosphatase 1B (PTP...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md17030166
更新日期：2019-03-14 00:00:00
abstract：:In order to search for sulfated polysaccharides in different invertebrate connective tissues and to examine their biological activities, we have isolated three types of polysaccharides from the body wall of the three sea cucumbers Holothuria edulis, Apostichopus japonicas and Holothuria nobilis. The physicochemical pr...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md11020399
更新日期：2013-02-05 00:00:00
abstract：:Being able to quantify ichthyotoxic metabolites from microalgae allows for the determination of ecologically-relevant concentrations that can be simulated in laboratory experiments, as well as to investigate bioaccumulation and degradation. Here, the ichthyotoxin karmitoxin, produced by Karlodinium armiger, was quanti...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md15090278
更新日期：2017-08-31 00:00:00
abstract：:Three new aryl alkaloids named suberitamides A-C (1-3), were isolated from an extract of the marine sponge Pseudosuberites sp. collected along the coast of North Carolina. Their planar structures were established by extensive nuclear magnetic resonance (NMR) and mass spectrometry (MS) analysis. To assign the challengi...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md18110536
更新日期：2020-10-28 00:00:00
abstract：:A bioactivity guided study of a cf. Caldora penicillata species, collected during a 2013 expedition to the Pacific island of Saipan, Northern Mariana Islands (a commonwealth of the USA), led to the isolation of a new thiazoline-containing alkaloid, laucysteinamide A (1). Laucysteinamide A is a new monomeric analogue o...
journal_title：Marine drugs
pub_type： 杂志文章
doi：10.3390/md15040121
更新日期：2017-04-14 00:00:00
abstract：:Agar, alginate, and carrageenans are high-value seaweed hydrocolloids, which are used as gelation and thickening agents in different food, pharmaceutical, and biotechnological applications. The annual global production of these hydrocolloids has recently reached 100,000 tons with a gross market value just above US$ 1....
journal_title：Marine drugs
pub_type： 杂志文章,评审
doi：10.3390/md13063340
更新日期：2015-05-27 00:00:00
