Abstract:
:Experiments have shown that suitably diluted, unpurified IgA paraprotein sera can be substituted for chemically purified IgA proteins in the passive haemagglutination test for the detection of anti-IgA antibodies. The substitution of unpurified IgA paraprotein was made possible by the enhanced serological activity obtained by pre-heating the unpurified immunoglobulin preparations at 56 degrees C for 60 min. Using a small screening panel of suitably coated tanned red cells, various population groups were investigated for the presence of anti-IgA antibodies. Results were similar to those obtained by other workers using purified IgA preparations in the passive haemagglutination test.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Hunt A,Reed Mdoi
10.1111/j.1423-0410.1990.tb02110.xsubject
Has Abstractpub_date
1990-01-01 00:00:00pages
30-3issue
1eissn
0042-9007issn
1423-0410journal_volume
59pub_type
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