Benefits and complications of regular blood transfusion in patients with beta-thalassaemia major.

abstract：:Alanine aminotransferase (ALT), gamma-glutamyl-transferase and hepatitis B core antibodies were evaluated as donor markers in a prospective study of 685 open-heart surgery patients. Of these three surrogate markers, only an ALT level greater than or equal to 2 SD above the log mean had a significant association with r...

journal_title：Vox sanguinis

authors： Ebeling F

更新日期：1991-01-01 00:00:00

abstract：:A selected group of women previously immunized in pregnancy by the Rh(D) antigen were boosted with 0.5 ml of Rh(D)-positive frozen recovered red cells from an accredited donor panel. The response was prompt and sustained and increased the anti-D content by almost 10-fold. In spite of the reduced rate of clinical immun...

journal_title：Vox sanguinis

authors： Gabra GS,Black M,Mitchell R

更新日期：1986-01-01 00:00:00

abstract：:2 patients on the drug azapropazone developed positive antiglobulin tests. Their sera were each found to contain two distinct antibodies. One was an IgG antibody, probably a drug-dependent autoantibody of the alpha-methyldopa type, but could have been related to the disease. The other was certainly a drug-dependent an...

journal_title：Vox sanguinis

authors： Bird GW,Wingham J,Babb RG,Bacon P,Wood D

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Aggregates often appear during apheresis. Sometimes, these persist throughout storage, causing product wastage. This study assessed product quality of apheresis concentrates containing persistent aggregates (PA) and aimed to identify the factors that contribute to their formation. METHODS:Donation (n = 180)...

journal_title：Vox sanguinis

authors： Feys HB,Coene J,Devloo R,Van Aelst B,Pottel H,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There are conflicting data regarding the therapeutic efficacy of platelets inactivated using amotosalen and ultraviolet A light. We have performed a meta-analysis to summarize the results of different randomized controlled trials (RCT). MATERIALS AND METHODS:Five RCTs reported through March 2...

journal_title：Vox sanguinis

authors： Cid J,Escolar G,Lozano M

更新日期：2012-11-01 00:00:00

abstract：:The presence of the glycoproteins haptoglobin and hemopexin in human plasma albumin (HPA) solutions were demonstrated to be responsible for the formation of polymers and aggregates during heat treatment for 10 h at 60 degrees C. Apart from haptoglobin and hemopexin three other contaminating proteins were identified as...

journal_title：Vox sanguinis

authors： Jensen LB,Dam J,Teisner B

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This article aims to characterize some elements that define the organizational models of healthcare actions in the field of blood and blood products. MATERIALS AND METHODS:This exploratory and qualitative study was carried out based on a documentary survey complemented by interviews with key ...

journal_title：Vox sanguinis

authors： Souza MKB

更新日期：2018-05-21 00:00:00

abstract：:The mechanism of CD4+ lymphocyte depletion, which is the main immunological feature in HIV-infected patients, is unclear. We investigated whether gp120-immunoglobulin-complement complexes on the surface of CD4+ cells might be involved in the elimination of CD4+ lymphocytes. The results obtained in 63 HIV-infected pati...

journal_title：Vox sanguinis

authors： Daniel V,Süsal C,Prodeus AP,Weimer R,Zimmermann R,Huth-Kühne A,Opelz G

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Despite long being a mainstay in describing platelet activation via degranulation, interlaboratory variation remains an issue in measurement of membrane CD62P by flow cytometry. Our objective was to identify actions that may minimize this variation. MATERIALS AND METHODS:Sixteen laboratories ...

journal_title：Vox sanguinis

authors： Levin E,Serrano K,Devine DV,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Rh phenotypes hrB- and VS+ are both rare in Whites but more common in Blacks. The high-incidence antigen hrB is present on most red cells that are e+. The presence of VS on red cells is associated with an aberrant expression of e, often called eS. MATERIALS AND METHODS:Using conventional ...

journal_title：Vox sanguinis

authors： Reid ME,Storry JR,Issitt PD,Combs MR,Beal CL,Mallory DA,Blancher A

更新日期：1997-01-01 00:00:00

abstract：:An autoantibody mimicking anti-S specificity is described in an S-s+ patient. The antibody was detected 2 weeks after transfusion. The direct antiglobulin test (DAT) was positive and the antibody was thought to be an alloantibody formed after the transfusion. Eighteen months later, the DAT was still positive and anti-...

journal_title：Vox sanguinis

authors： Puig N,Carbonell F,Soler MA,Perez MT,Arriaga F,Marty ML

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:The platelet gel is made by embedding concentrate platelets within a semisolid (gel) network of polymerized fibrin. It is believed that this blood component will be used more and more in the treatment of several clinical conditions and as an adjunctive material in tissue engineering. Several systems are avai...

journal_title：Vox sanguinis

authors： Mazzucco L,Balbo V,Cattana E,Borzini P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Repeated blood donation produces iron deficiency. Changes in dietary iron intake do not prevent donation-induced iron deficiency. Prolonging the interdonation interval or using oral iron supplements can mitigate donation-induced iron deficiency. The most effective operational methods for reduc...

journal_title：Vox sanguinis

authors： Bialkowski W,Bryant BJ,Schlumpf KS,Wright DJ,Birch R,Kiss JE,D'Andrea P,Cable RG,Spencer BR,Vij V,Mast AE

更新日期：2015-02-01 00:00:00

abstract：:The formation of mono(ethylhexyl)phthalate (MEHP) from di(ethylhexyl)phthalate in human plasma stored in bags of polyvinylchloride has been studied. Substantial amounts were formed and in ten bags from 4 to 56microgram/ml were found. After 2 weeks at room temperature the concentration of MEHP had increased to values b...

journal_title：Vox sanguinis

authors： Vessman J,Rietz G

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Apheresis platelet concentrates sometimes contain persistent aggregates (PA). Because apheresis involves extracorporeal circulation, we hypothesized that interactions between GPIbα and von Willebrand factor (VWF) underlie their origin. MATERIALS AND METHODS:Platelets in donations with PA were...

journal_title：Vox sanguinis

authors： Feys HB,Van Aelst B,Devloo R,Vandekerckhove P,Compernolle V

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There are no randomized trials comparing intravenous iron to RBC transfusion for the treatment of severe postpartum anaemia. The objectives of this study were to evaluate the feasibility of randomizing women with severe postpartum anaemia secondary to postpartum haemorrhage to RBC transfusion ...

journal_title：Vox sanguinis

authors： Holm C,Thomsen LL,Norgaard A,Langhoff-Roos J

更新日期：2017-02-01 00:00:00

abstract：:Radioimmunoassays were prepared using two anti-A and one anti-B reagents. The specificity of the procedures was assessed with 13 artificial antigens. The amounts of A and B natural antigens in saliva of ABH secretors of known Lewis phenotype were measured with these assays. The results confirmed that the average amoun...

journal_title：Vox sanguinis

authors： Le Pendu J,Lemieux RU,Dalix AM,Lambert F,Oriol R

更新日期：1983-01-01 00:00:00

abstract：:Isoagglutinins were investigated following ABO-incompatible bone marrow transplantation. In major incompatibility anti-A tends to require more time to disappear than anti-B. Correspondingly, A erythrocytes require more time to become demonstrable. There is no such difference in major plus minor incompatibility. In min...

journal_title：Vox sanguinis

authors： Wernet D,Mayer G

更新日期：1992-01-01 00:00:00

abstract：:The use of granulocyte transfusions in profoundly neutropenic patients has increased markedly in recent years. Whenever a pulmonary infiltrate develops during the course of these transfusions, the question arises as to what role the transfusions are playing and whether the transfusions should be discontinued to preven...

journal_title：Vox sanguinis

authors： Karp DD,Ervin TJ,Tuttle S,Gorgone BC,Lavin P,Yunis EJ

更新日期：1982-02-01 00:00:00

abstract：:The present report describes a technique for the production of monospecific rabbit antiserum to rat fibrinogen and its use in a quantitative radial immunodiffusion assay for measurement of rat fibrinogen and fibrin degradation products. It is a suitable technique for measurement of these parameters in small samples wh...

journal_title：Vox sanguinis

authors： Kaplan JE,Blumenstock FA,Saba TM

更新日期：1979-01-01 00:00:00

abstract：:The successful cloning of a non-structural antigen from the genome of what is now designated as the 'hepatitis C virus' (HCV) has transformed an erstwhile diagnosis of exclusion for non-A, non-B hepatitis (NANBH). The assay has been validated against panels of known infectivity for NANBH and sera from haemophiliac pat...

journal_title：Vox sanguinis

authors： Barbara JA,Contreras M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Serratia marcescens is a gram-negative bacterium that has been implicated in adverse transfusion reactions associated with contaminated platelet concentrates. The aim of this study was to investigate whether the ability of S. marcescens to form surface-attached aggregates (biofilms) could acco...

journal_title：Vox sanguinis

authors： Greco-Stewart VS,Brown EE,Parr C,Kalab M,Jacobs MR,Yomtovian RA,Ramírez-Arcos SM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Red-blood-cell (RBC) transfusion is associated with lung injury, which is further exacerbated by mechanical ventilation. Manufacturing methods of blood products differ globally and may play a role in the induction of pulmonary cell activation through alteration of the immunomodulatory property...

journal_title：Vox sanguinis

authors： Wirtz MR,Almizraq RJ,Weber NC,Norris PJ,Pandey S,Spinella PC,Muszynski JA,P Acker J,Juffermans NP

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:For some unknown reason humans may 'spontaneously' produce high amounts of neutralizing autoantibodies to a number of growth factors and cytokines. Reaching a certain high level the antibodies render the person cytokine deficient, mostly without overt clinical manifestations. The autoantibodies in question a...

journal_title：Vox sanguinis

authors： Hansen MB,Galle P,Salomo M,Svenson M,Dickmeiss E,Gimsing P

更新日期：2007-04-01 00:00:00

abstract：:A new red blood cell (RBC) cold autoantibody (anti-Me) is presented which was detected in a patient with autoimmune hemolytic anemia of 'cold type' associated with Waldenström's macroglobulinemia. The autoantibody was of the IgM (Kappa) class, had a moderate titer, and reacted with cord as well as with adult RBC. Its ...

journal_title：Vox sanguinis

authors： Salama A,Pralle H,Mueller-Eckhardt C

更新日期：1985-01-01 00:00:00

abstract：:Auto-immune haemolytic anaemia (AIHA) has been found in a case of alpha-interferon treatment. Serum antibody and eluate were positive in the absence of the drug. Although the patient recovered after the treatment was stopped, DAGT remained positive for at least 8 months. The mechanism proposed to explain why this drug...

journal_title：Vox sanguinis

authors： Barbolla L,Paniagua C,Outeiriño J,Prieto E,Sánchez Fayos J

更新日期：1993-01-01 00:00:00

abstract：:A sandwich-type solid phase radioimmunoassay, FRC-RIA (Finnish Red Cross-RIA) for hepatitis B surface antigen (HBsAg) is described. Polystyrene test tubes coated with sheep anti-HBs gamma-globulin serve as the solid phase. The technique is specific and has a sensitivity of about 1 ng/ml for the subtypes ad and ay of H...

journal_title：Vox sanguinis

authors： Koistinen V

更新日期：1978-01-01 00:00:00

abstract：:This report describes a case of persistent polyagglutinability restriced to the red blood cells, and associated with hemolytic anemia in a 20-year-old male. AIME WITH NORMAL INTERVALS. His red blood cells were weakly agglutinated by almost all adult sera. No autoagglutination was noted and the direct antihuman globuli...

journal_title：Vox sanguinis

authors： Graninger W,Rameis H,Fischer K,Poschmann A,Bird GW,Wingham J,Neumann E

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Fever is described in transfusion-associated circulatory overload (TACO), reflecting either comprehensive haemovigilance or an inflammatory pathobiology (such as congestion-associated atheroma disruptions). METHODS:Hospital haemovigilance data (1/1/2010-31/12/2012) were reviewed for TACO cases (frequency an...

journal_title：Vox sanguinis

authors： Parmar N,Pendergrast J,Lieberman L,Lin Y,Callum J,Cserti-Gazdewich C

更新日期：2017-01-01 00:00:00

abstract：:A Du variant negro woman developed, during pregnancy, an anti-D that was unusual in that it bound complement. The Rh groups of the propositus and other members of her family were also unusual. ...

journal_title：Vox sanguinis

authors： Ayland J,Horton MA,Tippett P,Waters AH

更新日期：1978-01-01 00:00:00