"VA", a new type of erythrocyte polyagglutination characterized by depressed H receptors and associated with hemolytic anemia. I. Serological and hematological observations.

abstract：:Manual plasmapheresis is done worldwide on both paid donors, and to a much smaller extent on volunteer donors in order to generate source plasma to be fractionated into albumin, clotting factor concentrates, and gamma globulin. Automated technology has now been developed utilizing both centrifugal, and membrane separa...

journal_title：Vox sanguinis

authors： Gilcher RO

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Necrotizing enterocolitis (NEC) is a common and often severe gastrointestinal emergency in newborn infants. While usually affecting (very) premature infants, an association between NEC and haemolytic disease of the foetus and newborn (HDFN) has been suggested. HDFN may be an additional risk fa...

journal_title：Vox sanguinis

authors： Ree IMC,de Grauw AM,Bekker V,de Haas M,Te Pas AB,Oepkes D,Middeldorp AJM,Lopriore E

更新日期：2020-02-01 00:00:00

abstract：:A new red blood cell (RBC) cold autoantibody (anti-Me) is presented which was detected in a patient with autoimmune hemolytic anemia of 'cold type' associated with Waldenström's macroglobulinemia. The autoantibody was of the IgM (Kappa) class, had a moderate titer, and reacted with cord as well as with adult RBC. Its ...

journal_title：Vox sanguinis

authors： Salama A,Pralle H,Mueller-Eckhardt C

更新日期：1985-01-01 00:00:00

abstract：:Recently, the polymorphism of a new human platelet antigen, Ca/Tu, was shown to be derived from a G-A nucleotide substitution at base 1564 of GPIIIa cDNA, which leads to a single amino acid difference, Arg/Gln at amino acid 489 of GPIIIa. We developed a PCR-RFLP method to determine the genotypes of Ca/Tu and their fre...

journal_title：Vox sanguinis

authors： Tanaka S,Taniue A,Nagao N,Tomita T,Ohnoki S,Shibata H,Okubo Y,Yamaguchi H,Shibata Y

更新日期：1996-01-01 00:00:00

abstract：:Inhibitor development represents the main complication in the treatment of haemophilia A. The risk of inhibitor formation is in part genetically determined by the type of the underlying factor VIII gene lesion but environmental factors may also play an important role. Due to the lack of efficiency of factor VIII in th...

journal_title：Vox sanguinis

authors： Brackmann HH,Schwaab R,Effenberger W,Hess L,Hanfland P,Oldenburg J

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Photochemical treatment (PCT) of platelet concentrates using photosensitizers and ultraviolet light illumination reduces the proliferation potential of pathogens by damaging biomolecules. MATERIALS AND METHODS:The impact of riboflavin (RF-PRT)- and amotosalen (AS-PCT)-based pathogen inactivation on platelet...

journal_title：Vox sanguinis

authors： Van Aelst B,Feys HB,Devloo R,Vanhoorelbeke K,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Plasma exchange (PE) and immunoadsorption with the Immusorba TR-350 column (IA) are used to remove autoantibodies from plasma in acute neurological autoimmune disorders. The impact of IA on coagulation and on low molecular weight heparin (LMWH) levels in comparison with PE was investigated. P...

journal_title：Vox sanguinis

authors： Koessler J,Kobsar A,Kuhn S,Koessler A,Yilmaz P,Weinig E,Putz E,Boeck M,Klinker E

更新日期：2015-01-01 00:00:00

abstract：:We have employed a PCR approach to determine the nucleotide sequences of the coding region in the last two coding exons of the histo-blood group ABO genes from one A(X) and one B(A) individual. Compared with A1 alleles, the (A(X)) allele has a single nucleotide substitution (T-->A at nucleotide 646) resulting in an am...

journal_title：Vox sanguinis

authors： Yamamoto F,McNeill PD,Yamamoto M,Hakomori S,Harris T

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It is sometimes difficult to obtain antigen-negative red blood cells (RBCs) for patients with antibodies against RBCs. However, the frequency and severity of the adverse reactions have not been well elucidated. Here, we conducted a multi-institutional collaborative study to clarify the backgro...

journal_title：Vox sanguinis

authors： Yamada C,Takeshita A,Ohto H,Ishimaru K,Kawabata K,Nomaguchi Y,Haraguchi Y,Abe M,Sobue K,Takenouchi H,Takadate J,Kamimura M,Katai A,Kasai D,Minami Y,Sugimoto T,Michino J,Nagai K,Kumagai M,Hasegawa Y,Ishizuka K,Oh

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Human platelet growth factors (HPGF) are essential for tissue regeneration and may replace fetal bovine serum (FBS) in cell therapy. No method for the manufacture of standardized virally inactivated HPGF has been developed yet. STUDY DESIGN AND METHODS:Platelet concentrates (PC) were subjected to solvent/de...

journal_title：Vox sanguinis

authors： Su CY,Kuo YP,Lin YC,Huang CT,Tseng YH,Burnouf T

更新日期：2009-08-01 00:00:00

abstract：:The risk of non-A, non-B hepatitis transmission by an intravenous immunoglobulin (IVIG) preparation was assessed in a prospective multicenter trial in 68 patients with primary immunodeficiency disorders (40 children or adolescents and 28 adults). During the 4-week prestudy evaluation period the clinical examinations a...

journal_title：Vox sanguinis

authors： Imbach P,Perret BA,Babington R,Kaminski K,Morell A,Heiniger HJ

更新日期：1991-01-01 00:00:00

abstract：:In recent years the development of recombinant DNA and sequencing techniques has led to a greatly increased understanding of the genetic complexity, structure and function of the human major histocompatibility complex. This system may be subdivided into the "classical' HLA (human leukocyte antigen) class I and II tran...

journal_title：Vox sanguinis

authors： Howell WM,Navarrete C

更新日期：1996-01-01 00:00:00

abstract：:The MAIEA (monoclonal-antibody-specific immobilisation of erythrocyte antigens) assay has recently been developed for the assignment of red cell antigens, recognised by human alloantisera, to particular membrane components of the red cell membrane. This technique detects trimolecular complexes formed by the reaction o...

journal_title：Vox sanguinis

authors： Petty AC,Daniels GL,Anstee DJ,Tippett P

更新日期：1993-01-01 00:00:00

abstract：:Because substrate specificities differ between proteolytic enzymes and because knowledge of the optimal enzyme activity levels is necessary in order to standardize procedures used in antibody screening, a study was made of the best common assay method for the routinely employed enzymes bromelain, papain and ficin. Cas...

journal_title：Vox sanguinis

authors： Ogasawara K,Mazda T

更新日期：1989-01-01 00:00:00

abstract：:Recently, we have shown that thiopyrylium has robust inactivation capabilities against a broad spectrum of pathogens in the human red blood cell (RBC) suspensions while retaining key RBC in vitro properties. The 24-h recovery and survival of canine red cells were measured upon autologus reinfusion of control and photo...

journal_title：Vox sanguinis

authors： Skripchenko A,Balch A,Mackin A,Wagner SJ

更新日期：2007-02-01 00:00:00

abstract：:The clinical course and laboratory findings of a patient with autoimmune haemolytic anaemia due to anti-phospholipid antibodies and secondary to a systemic lupus erythematosus-like syndrome are described. IgG and IgM with anti-phospholipid activity coexisted in both sera and acid eluates prepared from the patient's re...

journal_title：Vox sanguinis

authors： Arvieux J,Schweizer B,Roussel B,Colomb MG

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Neonatal alloimmune thrombocytopenia is usually attributable to HPA-la antibodies. We report a case of parental platelet antigen incompatibility associated with a severe neonatal thrombocytopenia secondary to alloimmunization to HPA-3a. MATERIALS AND METHODS:Platelet antibodies were detected ...

journal_title：Vox sanguinis

authors： Boehlen F,Kaplan C,de Moerloose P

更新日期：1998-01-01 00:00:00

abstract：:With regard to hemostasis and thrombosis, collagens are among the most important physiologic components of the extracellular matrix in their role as platelet activators. Differences in the rate of platelet activation markedly influence normal hemostasis and the pathological outcome of thrombosis. Thus, collagen recept...

journal_title：Vox sanguinis

authors： Kunicki TJ,Nugent DJ

更新日期：2002-08-01 00:00:00

abstract：:Metabolic properties of standard gamma globulin (St-GG) and of several gamma globulin (GG) preparations for intravenous use were analyzed in radioactive tracer studies. The in vivo behaviour of St-GG was investigated in 16 probands and found to be comparable to that of normal IgG. The kinetics of the resorption of St-...

journal_title：Vox sanguinis

authors： Morell A,Schürch B,Ryser D,Hofer F,Skvaril F,Barandun S

更新日期：1980-01-01 00:00:00

abstract：:Immunoblotting with human anti-Sc1 and anti-Sc2 locates the Sc1 and Sc2 antigens to an erythrocyte membrane glycoprotein of apparent Mr 60,000. The antigens are destroyed by pronase, and require intact disulphide bonds for expression. A proportion of the molecules carrying the Sc1 and Sc2 antigens are associated with ...

journal_title：Vox sanguinis

authors： Spring FA,Herron R,Rowe G

更新日期：1990-01-01 00:00:00

abstract：:The successful cloning of a non-structural antigen from the genome of what is now designated as the 'hepatitis C virus' (HCV) has transformed an erstwhile diagnosis of exclusion for non-A, non-B hepatitis (NANBH). The assay has been validated against panels of known infectivity for NANBH and sera from haemophiliac pat...

journal_title：Vox sanguinis

authors： Barbara JA,Contreras M

更新日期：1991-01-01 00:00:00

abstract：:During the course of septicaemia, a group A1 patient developed several RBC antigenic modifications. Acquired B antigen, Tk transformation and a partial disappearance of A1 receptors associated with an increase of H reactivity were observed. ...

journal_title：Vox sanguinis

authors： Byrne V,Brown A,Ropars C,Moore BP

更新日期：1979-01-01 00:00:00

abstract：:Blood transfusion practices have evolved empirically, with few or no research data supporting them. In the past several decades, fuelled by fears of infection and reports of mistakes, patients have increasingly demanded their rights to choice, both in the components given to them as well as to refuse to receive these ...

journal_title：Vox sanguinis

authors： Sazama K

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:For some unknown reason humans may 'spontaneously' produce high amounts of neutralizing autoantibodies to a number of growth factors and cytokines. Reaching a certain high level the antibodies render the person cytokine deficient, mostly without overt clinical manifestations. The autoantibodies in question a...

journal_title：Vox sanguinis

authors： Hansen MB,Galle P,Salomo M,Svenson M,Dickmeiss E,Gimsing P

更新日期：2007-04-01 00:00:00

abstract：:Three examples of an antibody were found to be detecting a red cell polymorphism probably identical to MER2. The antibodies were made by Jews originating from India and living in Israel. Two of them were sibs and the third was unrelated. All 3 had kidney disease requiring renal dialysis and regular blood transfusion. ...

journal_title：Vox sanguinis

authors： Daniels GL,Levene C,Berrebi A,Schechter Y,Moulds M,Sela R,Poole J,Lacey P,Atkins CJ

更新日期：1988-01-01 00:00:00

abstract：:Forty-six subjects (44 HIV antibody-positive) with some degree of immune deficiency (at least TH/TS ratio below 1) were randomly distributed into 4 treatment groups. Each group was assigned to 1 of 4 products to be used exclusively for a 1-year period: 1 concentrate was of intermediate purity and not heat-treated, and...

journal_title：Vox sanguinis

authors： Allain JP,Frommel D,Bosser C,Gazengel C,Larrieu MJ,Sultan Y

更新日期：1987-01-01 00:00:00

abstract：:The panagglutination phenomenon described by Thomsen and Friedenreich (TF) is due to the reaction of naturally occurring TF-antibodies with the carbohydrate group beta-D-Gal-(1-3)-D-GalNAc of desialylated glycophorin A, the major glycoprotein component of the erythrocyte membrane. The specificity of human TF-antibodie...

journal_title：Vox sanguinis

authors： Höppner W,Fischer K,Poschmann A,Paulsen H

更新日期：1985-01-01 00:00:00

abstract：:We have studied the IgE content of different lots of commercial intravenous IgG preparations used in our day hospital as replacement therapy for patients with agammaglobulinemia. Two enzymatic methods were used: Phadezym and FAST. The average amounts of IgE detected in Endobulin and Sandoglobulin lots were very high w...

journal_title：Vox sanguinis

authors： Paganelli R,Quinti I,D'Offizi GP,Papetti C,Cabello A,Aiuti F

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previous data that showed maintenance of reticulocyte percentage in whole blood stored in CPDA-1 have led to the assumption that reticulocyte maturation becomes arrested during refrigerated storage. However, reticulocyte behaviour in red-blood-cell units stored in additive solutions has not ye...

journal_title：Vox sanguinis

authors： Urbina A,Palomino F

更新日期：2013-05-01 00:00:00

abstract：:We studied 684 sera obtained from 20 hemophilia patients with AIDS/AIDS-related complex (ARC), 89 asymptomatic HIV+, 76 HIV- hemophilia patients and 151 healthy controls for antibodies against recombinant CD4 (rCD4). Twenty-two percent of AIDS/ARC patients, 10% of asymptomatic HIV+ patients, 17% of HIV-patients, and 1...

journal_title：Vox sanguinis

authors： Daniel V,Weimer R,Zettlmeissl G,Langner K,Zimmermann R,Opelz G

更新日期：1992-01-01 00:00:00