Abstract:
:The clinical course and laboratory findings of a patient with autoimmune haemolytic anaemia due to anti-phospholipid antibodies and secondary to a systemic lupus erythematosus-like syndrome are described. IgG and IgM with anti-phospholipid activity coexisted in both sera and acid eluates prepared from the patient's red cells, as demonstrated by ELISA using a panel of anionic and neutral phospholipids. The anti-erythrocyte binding activity of eluted autoantibodies, determined by a radioactive antiglobulin technique, was totally inhibited by absorption with phospholipid micelles. The patient's serum also contained an IgM warm haemolysin detectable with enzyme-treated cells only, as well as anti-C, -E and -S alloantibodies.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Arvieux J,Schweizer B,Roussel B,Colomb MGdoi
10.1111/j.1423-0410.1991.tb00945.xsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
190-5issue
3eissn
0042-9007issn
1423-0410journal_volume
61pub_type
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