A virally inactivated functional growth factor preparation from human platelet concentrates.

abstract：:A simple method, based on ethanol fractionation, for the preparation of highly purified human serum albumin with a higher yield than that of the conventional ethanol procedures is described. It consists of two purification steps, namely, precipitation of most of the other plasma proteins from a 3-fold diluted plasma w...

journal_title：Vox sanguinis

authors： Hao Y

更新日期：1979-01-01 00:00:00

abstract：:The polymorphism of the second component of human complement was studied by means of isoelectric focusing in polyacrylamide gels with subsequent complement-dependent lysis of sensitized sheep erythrocytes in an agarose overlay containing C2-deficient or normal human serum. In a material of 289 unrelated individuals th...

journal_title：Vox sanguinis

authors： Dewald G,Rittner C

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There is concern regarding the lack of prevention of unnecessary transfusion of RhD negative red cells and unnecessary administration of Rh immunoglobulin (RhIG) to pregnant women. In this study, performance of ID RHD XT, a genotyping assay for identification of six RHD allelic variants and hu...

journal_title：Vox sanguinis

authors： Londero D,Monge J,Hellberg A

更新日期：2020-04-01 00:00:00

abstract：:The use of granulocyte transfusions in profoundly neutropenic patients has increased markedly in recent years. Whenever a pulmonary infiltrate develops during the course of these transfusions, the question arises as to what role the transfusions are playing and whether the transfusions should be discontinued to preven...

journal_title：Vox sanguinis

authors： Karp DD,Ervin TJ,Tuttle S,Gorgone BC,Lavin P,Yunis EJ

更新日期：1982-02-01 00:00:00

abstract：:A pilot study for large-scale automated plasmapheresis using the Haemonetics Model 50 machine was undertaken in the Yorkshire Region of the United Kingdom to determine the viability of such a programme for national self-sufficiency in fresh plasma procurement for factor VIII concentrate production. The study was desig...

journal_title：Vox sanguinis

authors： Robinson AE,Penny AF,Smith J,Tovey DL

更新日期：1983-03-01 00:00:00

abstract：:False-positive enzyme immunoassay (EIA) tests in blood donors receiving influenza vaccine were first reported in 1991. We conducted follow-up testing for 6 months of those donors with multiply reactive, but unconfirmed EIA (at least 2 positives in anti-HCV-1.0, anti-HIV-1, and anti-HTLV-I assays) with a history of rec...

journal_title：Vox sanguinis

authors： Arnold NL,Slade BA,Jones MM,Popovsky MA

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Early prediction of massive transfusion (MT) post-trauma may reduce mortality by earlier delivery of blood products. A clinical prediction tool (PWH score) for this purpose was developed at the Prince of Wales Hospital, Hong Kong. The aims of this study were to apply this tool to major trauma ...

journal_title：Vox sanguinis

authors： Mitra B,Rainer TH,Cameron PA

更新日期：2012-05-01 00:00:00

abstract：:Cytomegalovirus (CMV) can cause severe morbidity in immunosuppressed patients. Regional transfusion centres in the UK are required to supply high-titre anti-CMV plasma to the Blood Products Laboratory (BPL), now called 'Bio-Products Laboratory', for the production of specific intravenous immunoglobulin at the Protein ...

journal_title：Vox sanguinis

authors： McDonald C,Barbara JA,al-Izzi A,Contreras M

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Changes in in vitro platelet quality parameters during platelet storage are associated with a decrease of in vivo platelet viability after platelet transfusion. Many attempts have been made to identify the most predictable in vitro parameters for in vivo performance. We used a riboflavin-based...

journal_title：Vox sanguinis

authors： Goodrich RP,Li J,Pieters H,Crookes R,Roodt J,Heyns Adu P

更新日期：2006-05-01 00:00:00

abstract：:Activated protein C (APC) is a highly specific serine proteinase which functions as an important naturally occurring antithrombotic enzyme. APC also has anti-inflammatory properties. We have developed a large-scale process for the production of APC for therapeutic use starting with cryoprecipitate-poor human plasma. T...

journal_title：Vox sanguinis

authors： Orthner CL,Ralston AH,Gee D,Kent R,Kolen B,McGriff JD,Drohan WN

更新日期：1995-01-01 00:00:00

abstract：:A new competitive solid phase radioimmunoassay (CLB-RIA) has been developed for the detection of HBAg and HBAb in human serum and plasma. In the assay, sheep antibodies to HBAg, covalently linked to an insoluble carrier, highly purified 125-I labelled HBAg and the serum or plasma sample are incubated for 20 h at room ...

journal_title：Vox sanguinis

authors： Duimel WJ,Brummelhuis HG

更新日期：1975-01-01 00:00:00

abstract：:There is almost general agreement that removal of leukocytes from blood components reduces the incidence of HLA-antibody formation and refractoriness to random platelet transfusions. Recently filters have become available, which are able to reduce leukocyte contamination in platelet suspensions with acceptable platele...

journal_title：Vox sanguinis

authors： Novotny VM,van Doorn R,Rozier Y,D'Amaro J,Harvey MS,Brand A

更新日期：1992-01-01 00:00:00

abstract：:In a 2-year study involving 133 premature low birth weight (less than 1,500 g) infants, the impact of CMV infection via blood transfusion was assessed. 8.4% (7 out of 83) of transfused infants and 10% (7 out of 70) of those exposed to seropositive blood acquired CMV. In those less than 1,250 g the infection rate rose ...

journal_title：Vox sanguinis

authors： Galea G,Urbaniak SJ

更新日期：1992-01-01 00:00:00

abstract：:Some effector functions of various immunoglobulin (IgG) preparations have been compared. Tests for opsonic activity were performed in vitro with human peripheral blood leukocytes and in vivo with mice. The augmentation effects on luminol-dependent chemiluminescence were investigated with human leukocytes. The compleme...

journal_title：Vox sanguinis

authors： Yasuda H,Yajima T,Tanii T,Ashiba T,Iwata M

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Continuous-flow and intermittent-flow blood cell separators (CFCS and IFCS) are both used to collect stem cells from the blood to rescue patients undergoing myeloablative treatment for cancer. MATERIALS AND METHODS:We designed a study to compare the collection efficiency of the two systems. T...

journal_title：Vox sanguinis

authors： Beretta F,van den Bosch S,Castelli D,Cavalli F,Ghielmini M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:There have been recurrent shortages of group O blood due to insufficient inventory and use of group O blood in ABO non-identical recipients. We performed a 12-year retrospective study to determine utilization of group O Rh-positive and Rh-negative red blood cells (RBCs) by recipient ABO group. Reasons for tr...

journal_title：Vox sanguinis

authors： Barty RL,Pai M,Liu Y,Arnold DM,Cook RJ,Zeller MP,Heddle NM

更新日期：2017-05-01 00:00:00

abstract：:The Gm allotype constitution of the autoantibody molecules and the serum Gm phenotypes were determined in 19 patients with autiommune hemolytic anemia of IgG type. The results showed that the known heterogeneity of the antierythrocyte autoantibodies in this disease concerns not only the immunoglobulin class and the is...

journal_title：Vox sanguinis

authors： Le Petit JC,Rivat L,François N,Ropartz C,Brizard CP

更新日期：1976-01-01 00:00:00

abstract：:A number of parasitic diseases are known, or suspected to be transmitted by blood transfusion. Of greatest concern are malaria and Chagas' disease, but babesia, leishmania and toxoplasmosis also offer risk in particular locations or circumstances. Some of these parasites may be imported into non-endemic areas as a res...

journal_title：Vox sanguinis

authors： Dodd RY

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ross River virus (RRV) is an enveloped, RNA alphavirus in the same antigenic group as chikungunya virus. Australia records an annual average of 5000 laboratory-confirmed RRV infections. While RRV is currently geographically restricted to the Western Pacific, the capacity of arboviruses for rap...

journal_title：Vox sanguinis

authors： Seed CR,Hoad VC,Faddy HM,Kiely P,Keller AJ,Pink J

更新日期：2016-05-01 00:00:00

abstract：:alpha 1-Antitrypsin (AAT) has been purified from human plasma supernatant A (equivalent to COHN fraction II + III) by a large-scale chromatographic procedure involving anion-exchange adsorption on DEAE Sepharose CL-6B fast flow and size-exclusion chromatography on Sephacryl S-200. Before freeze-drying, the liquid conc...

journal_title：Vox sanguinis

authors： Burnouf T,Constans J,Clerc A,Descamps J,Martinache L,Goudemand M

更新日期：1987-01-01 00:00:00

abstract：:A 24-hours service was organized to study changes in the hemostatic system in surgical patients undergoing massive transfusion for excessive bleeding during operation or in the early postoperative period. Hemostasis tests gave normal results in only 12(7%) of the 172 patients, while in the remaining 160(93%) one or mo...

journal_title：Vox sanguinis

authors： Mannucci PM,Federici AB,Sirchia G

更新日期：1982-03-01 00:00:00

abstract：:Blood plasma and factor VIII concentrate have been fractionated by continuous free film electrophoresis in an apparatus which was designed to overcome the problems of overheating usually inherent in this technique. Results show that complete separation of plasma proteins is unlikely to be obtained by a single passage ...

journal_title：Vox sanguinis

authors： Austen DE,Cartwright T,Dickerson CH

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:The risk of transmitting hepatitis C (HCV) by transfusion of anti-HCV-negative screened blood was estimated for the blood donor population of Baden-Württemberg (southwestern Germany). METHODS:The data from the blood donors screened for anti-HCV and for HBsAg during 1990-1995 were analyzed. RESULTS:The preva...

journal_title：Vox sanguinis

authors： Koerner K,Cardoso M,Dengler T,Kerowgan M,Kubanek B

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The para-Bombay phenotype (also known as H-deficient secretor) is characterized by a lack of ABH antigens on red cells, but ABH substances are found in saliva. Molecular genetic analysis was performed for five Chinese individuals serologically typed as para-Bombay. MATERIALS AND METHODS:ABO g...

journal_title：Vox sanguinis

authors： Yip SP,Chee KY,Chan PY,Chow EY,Wong HF

更新日期：2002-10-01 00:00:00

abstract：:We performed a flow-cytometric analysis of the expression of D antigen in D+W samples (previously termed Du). We also analysed a series of D-positive and D-negative (cde phenotype) samples to obtain positive and negative controls, respectively. The evaluation was carried out by immunofluorescence and the intensity of ...

journal_title：Vox sanguinis

authors： Tazzari PL,Bontadini A,Belletti D,Malferrari F,Conte R

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:We have developed and optimised a new flow-cytometric method for the measurement of the Fc function of intravenous immunoglobulin (IVIg) preparations, which is important in predicting the effector function of immunoglobulin (Ig) in such preparations. MATERIALS AND METHODS:Ig was bound to a monocytic cell li...

journal_title：Vox sanguinis

authors： Ramasamy I,Tran E,Charnock A,Farrugia A

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The International Haemovigilance Network collects aggregate data on complications of blood donation from member haemovigilance systems (HVS). We analysed the data collected in 2006-2016 in order to learn from it and consider future improvements. MATERIALS AND METHODS:National HVS entered annu...

journal_title：Vox sanguinis

authors： Wiersum-Osselton JC,Politis C,Richardson C,Goto N,Grouzi E,Marano G,Land KJ

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The objective of the study was to investigate the splanchnic blood flow velocity and oximetry response to blood transfusion in preterm infants according to postnatal age. MATERIALS AND METHODS:Preterm infants receiving blood transfusion were recruited to three groups: 1-7 (group 1; n = 20), 8-...

journal_title：Vox sanguinis

authors： Banerjee J,Leung TS,Aladangady N

更新日期：2016-11-01 00:00:00

abstract：:Paraformaldehyde-fixed platelets from normal donors were used for detection of antibody to platelet by in vitro sensitization (indirect method) utilizing rabbit anti-human IgG heavy chain specific antibody-coated polyacrylamide gels (Immunobeads). The sensitized platelets formed rosettes with Immunobeads and the posit...

journal_title：Vox sanguinis

authors： Salmassi S,Yokoyama MM,Maples JA,Matsui Y

更新日期：1980-11-01 00:00:00

abstract：:Pst I endonuclease fragment length polymorphism of the antithrombin III probe was studied in a French population. Among 25 subjects tested, 15 were found heterozygous at the Pst I site, so that this polymorphism might serve as a useful markers of antithrombin III gene in families with antithrombin III deficiency. ...

journal_title：Vox sanguinis

authors： Le Paslier D,Rochu D,Lucotte G

更新日期：1985-01-01 00:00:00