Screening plasma donors for high-titre antibody to cytomegalovirus using a latex agglutination test.

abstract：BACKGROUND AND OBJECTIVES:GB virus C (GBV-C)/hepatitis G virus (HGV) is a recently recognized parenterally and sexually transmitted agent. The prevalence of GBV-C/HGV markers in Canadian blood donors has not been previously studied and was therefore determined. MATERIALS AND METHODS:Blood donors [identity unlinked (IU...

journal_title：Vox sanguinis

authors： Giulivi A,Slinger R,Tepper M,Sher G,Scalia V,Kessler G,Gill P

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Refrigerated storage of red blood cells (RBCs) induces numerous changes that may target the cells for erythrophagocytosis following transfusion. The influence of storage upon the phagocytosis of unseparated and fractionated young and old stored RBCs was investigated using two in vitro quantita...

journal_title：Vox sanguinis

authors： Veale MF,Healey G,Sparrow RL

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The low-prevalence Rh antigen, JAL, was named after the index case, Mr. J. Allen. Based on reactivity of seven multi-specific sera with his RBCs, it was apparent that they express at least one additional low-prevalence antigen. The purpose of this study was to investigate the other low-prevalence antigen(s) ...

journal_title：Vox sanguinis

authors： Hue-Roye K,Reid ME,Westhoff CM,Lomas-Francis C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Although transfusion-transmitted infections are rare, non-infectious complications occur relatively frequently. Solvent/detergent-treated fresh-frozen plasma (SD-FFP) has been shown to reduce the frequency of both types of complication, although previous economic evaluations failed to consider...

journal_title：Vox sanguinis

authors： Riedler GF,Haycox AR,Duggan AK,Dakin HA

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:A disposable set for platelet concentrate (PC) preparation by the buffy coat method allows pooling of buffy coats, centrifugation and cell separation with in-line leucocyte filtration. This study compares three commercially available pooling sets in combination with INTERCEPT pathogen inactivation (PI). MAT...

journal_title：Vox sanguinis

authors： Feys HB,Devloo R,Sabot B,Coene J,Compernolle V

更新日期：2018-05-24 00:00:00

abstract：:Present platelet storage media often designated platelet additive solutions (PAS) basically contain acetate, citrate and phosphate and recently also potassium and magnesium. However, there seems to be an increasing interest in developing PASs that can be used also after further reduction of residual plasma content bel...

journal_title：Vox sanguinis

authors： Gulliksson H

更新日期：2014-10-01 00:00:00

abstract：:An IgM kappa cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)-treated RBC. It resembled anti-Me cold agglutinin in these serological findings. However, the activity of this agglutinin against RBC was markedly de...

journal_title：Vox sanguinis

authors： Kajii E,Ikemoto S

更新日期：1989-01-01 00:00:00

abstract：:The etiologic agent for acquired immune deficiency syndrome (AIDS) has been identified as human T lymphotropic virus type III (HTLV-III). Its distinguishing characteristics and putative receptor, the T4 molecule, are discussed. The Western Blot method has been applied to assess the presence of antibody to HTLV-III in ...

journal_title：Vox sanguinis

authors： Pahwa S

更新日期：1986-01-01 00:00:00

abstract：:Most in vitro studies on microaggregate filters focus on the mechanical retention of microparticles. Data are based on bulk techniques such as differential dry weight and screen filtration pressure measurements or single-particle counting using resistance measurement (Coulter principle). Errors in measurements may res...

journal_title：Vox sanguinis

authors： Eisert WG,Eckert G

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previous studies with p38MAPK inhibitors at room temperature demonstrated that they improve a large number of platelet storage parameters, but cannot substantially inhibit p38MAPK activation nor protect against widespread decrements in platelet quality parameters during 4 °C storage. In this s...

journal_title：Vox sanguinis

authors： Wagner SJ,Skripchenko A,Seetharaman S,Kurtz J

更新日期：2015-04-01 00:00:00

abstract：:Anti-Sdx is an IgM complement-binding autoantibody that defines a red cell antigen which is independent of I, i, Sp1 (Pr) and Gd. Hemagglutination by the antibody is unusually sensitive to variation in pH, salt, or other charged molecular species. The antibody is inhibited by urine from Sd(a+) persons, but inhibition ...

journal_title：Vox sanguinis

authors： Bass LS,Rao AH,Goldstein J,Marsh WL

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:The platelet gel is made by embedding concentrate platelets within a semisolid (gel) network of polymerized fibrin. It is believed that this blood component will be used more and more in the treatment of several clinical conditions and as an adjunctive material in tissue engineering. Several systems are avai...

journal_title：Vox sanguinis

authors： Mazzucco L,Balbo V,Cattana E,Borzini P

更新日期：2008-04-01 00:00:00

abstract：:Articles on the appropriateness of intention-to-treat (ITT) vs. as-treated (AT) analyses of randomized controlled trials (RCTs) have highlighted issues relevant to drug trials, such as approaches suitable for 'explanatory' vs. 'pragmatic' RCTs. These considerations are less relevant to transfusion medicine RCTs, espec...

journal_title：Vox sanguinis

authors： Vamvakas EC

更新日期：2008-10-01 00:00:00

abstract：:Two previously unpublished low-incidence antigens, Jones and Hol., are identical. The antigen is a dominant, autosomally inherited character that segregates independently from the loci for the ABO, MNS, Duffy and Yt blood group systems and is different from previously published infrequent antigens. The antigen is appa...

journal_title：Vox sanguinis

authors： Reid M,Fischer ML,Green C,Rowe GP,Pfister M,Poole J,Lewis M

更新日期：1989-01-01 00:00:00

abstract：:The risk of non-A, non-B hepatitis transmission by an intravenous immunoglobulin (IVIG) preparation was assessed in a prospective multicenter trial in 68 patients with primary immunodeficiency disorders (40 children or adolescents and 28 adults). During the 4-week prestudy evaluation period the clinical examinations a...

journal_title：Vox sanguinis

authors： Imbach P,Perret BA,Babington R,Kaminski K,Morell A,Heiniger HJ

更新日期：1991-01-01 00:00:00

abstract：:We report a preliminary study on whether syphilis serology might be reactive in some blood donors at risk for human immunodeficiency virus (HIV) infection. We retrospectively analyzed voluntary blood donations with reactive Treponema pallidum antibody (TPA) tests according to the type of donation, the presence of othe...

journal_title：Vox sanguinis

authors： Ramsey G,Soltis F,Bowman R,McNamee J,Hahn LF,Dixon BW

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Intraoperative autologous blood recovery during radical retro pubic prostatectomy has the potential of contamination with tumour cells. Its safety is proved by similar survival rates between allogeneic and autologous transfusion to oncology patients without standardization. Silencing of the gen...

journal_title：Vox sanguinis

authors： Poli M,Camargo A,Villa L,Moura R,Colella R,Deheinzelin D

更新日期：2008-11-01 00:00:00

abstract：:The presence of IgM antibodies to human immunodeficiency virus 1 (HIV-1) was investigated in blood donor sera which were indeterminate in anti-HIV-1 IgG Western blot testing. In 7 of 173 instances out of approximately 1,000,000 blood donation sera with an isolated anti-p24 IgG produced an anti-gp41-45 IgM immunoblot r...

journal_title：Vox sanguinis

authors： Knüver-Hopf J,Heinze H,Lambrecht B,Mohr H,Beyer J,Schmitt H

更新日期：1993-01-01 00:00:00

abstract：:Hepatitis A virus (HAV) infections have been reported among hemophiliacs who received factor VIII concentrates which had been purified by ion-exchange chromatography and treated by the solvent detergent (SD) method. Since the virus inactivation procedure of our manufacturing process is heat treatment of the stabilized...

journal_title：Vox sanguinis

authors： Hilfenhaus J,Nowak T

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The absence of the red cell antigens P, P1 and Pk , known as 'p', represents an extremely rare red cell phenotype. Individuals with this phenotype spontaneously form anti-PP1Pk isoantibodies, associated with severe haemolytic transfusion reactions, recurrent spontaneous abortion and haemolytic disease of the...

journal_title：Vox sanguinis

authors： Di Ciaccio P,Cutts B,Alahakoon TI,Dennington PM,Soo LA,Curnow J

更新日期：2020-12-16 00:00:00

abstract：:Red cells of the McLeod phenotype in the Kell blood group system have an acanthocytic morphology. The membrane protein composition analyzed on sodium dodecyl-sulfate-polyacrylamide gel electrophoresis, the ATP level and the activities of a large number of intracellular enzymes appear to be normal. Membranes prepared f...

journal_title：Vox sanguinis

authors： Tang LL,Redman CM,Williams D,Marsh WL

更新日期：1981-01-01 00:00:00

abstract：:Baboon red cells were treated to reduce oxygen affinity by an osmotic-pulse procedure using dimethyl-sulfoxide. Inositol hexaphosphate (IHP) alone or IHP and adenosine triphosphate (ATP) were incorporated into the red cells in the presence of polyethylene glycol (PEG). The procedure produced variable increases in the ...

journal_title：Vox sanguinis

authors： Franco RS,Weiner M,Wagner K,Martelo OJ,Ragno G,Pivacek LE,Valeri CR

更新日期：1988-01-01 00:00:00

abstract：:alpha 1-Antitrypsin (AAT) has been purified from human plasma supernatant A (equivalent to COHN fraction II + III) by a large-scale chromatographic procedure involving anion-exchange adsorption on DEAE Sepharose CL-6B fast flow and size-exclusion chromatography on Sephacryl S-200. Before freeze-drying, the liquid conc...

journal_title：Vox sanguinis

authors： Burnouf T,Constans J,Clerc A,Descamps J,Martinache L,Goudemand M

更新日期：1987-01-01 00:00:00

abstract：:Following transfusion, red cells labeled with nonradioactive chromium (52Cr) can be detected in the circulation using atomic absorption spectrophotometry. Both in rhesus monkeys and in human subjects, the survival of red cells labeled with 52Cr was found to be insignificantly different from that of cells labeled with ...

journal_title：Vox sanguinis

authors： Sioufi HA,Button LN,Jacobson MS,Kevy SV

更新日期：1990-01-01 00:00:00

abstract：:A panel of 50 blood group antibodies covering a range of blood group antigens has been tested in the presence of 0.25% beta-propiolactone as a possible means of reducing infectivity of high-risk HTLV III/HBsAg samples. 11/50 (22%) antibodies could not be detected by the indirect antiglobulin test, and 6/40 (15%) were ...

journal_title：Vox sanguinis

authors： Hunt AF,Jones MT,Howkins GJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In previous studies, we found that platelet microparticles (PMPs) bind to cord blood (CB) CD34+ cells and transfer adhesion molecules to them, which enhances their engraftment. Before applying this phenomenon in actual transplants, we investigated the effect of PMPs on cryopreserved CD34+ cell...

journal_title：Vox sanguinis

authors： Liu B,Chen JS,Cao M,Gu SL,Liao C,Li DZ,Zhong HZ

更新日期：2004-08-01 00:00:00

abstract：:The second example of anti-F1 cold agglutinins recognizing a developmentally regulated antigen like I is described. The antibody occurred transiently and simultaneously together with an anti-I cold agglutinin. Although anti-F1 and anti-I specificities are entirely different, the data on the biochemistry of F1 and I an...

journal_title：Vox sanguinis

authors： Roelcke D,Weber MT

更新日期：1984-01-01 00:00:00

abstract：:The mechanism of CD4+ lymphocyte depletion, which is the main immunological feature in HIV-infected patients, is unclear. We investigated whether gp120-immunoglobulin-complement complexes on the surface of CD4+ cells might be involved in the elimination of CD4+ lymphocytes. The results obtained in 63 HIV-infected pati...

journal_title：Vox sanguinis

authors： Daniel V,Süsal C,Prodeus AP,Weimer R,Zimmermann R,Huth-Kühne A,Opelz G

更新日期：1993-01-01 00:00:00

abstract：:Mild as well as strong periodate oxidation of isolated erythrocyte N and M glycoproteins and glycopeptides gave extensive to complete destruction of N-specificities as measured with Vicia graminea extracts and of N- as well as M- activities determined with all but 1 of 8 animal anti-N and 13 anti-M sera. Results with ...

journal_title：Vox sanguinis

authors： Springer GF,Yang HJ

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Staphylococcus epidermidis is a predominant contaminant of platelet concentrates (PCs), outcompeting other skin flora bacteria such as Staphylococcus capitis. The accumulation-associated protein (Aap), encoded by the aap gene, is involved in formation of bacterial aggregates (biofilms) in S. e...

journal_title：Vox sanguinis

authors： Alabdullatif M,Ramirez-Arcos S

更新日期：2019-01-01 00:00:00