Blood donations indeterminate in HIV-1 western blot analysed by IgM immunoblot and polymerase chain reaction.

abstract：:Tissue oxygen delivery depends on red blood cell (RBC) content and RBC flow regulation in the microcirculation. The important role of the RBC in tissue oxygenation is clear from anaemia and the use of RBC transfusion which has saved many lives. Whether RBC transfusion actually restores tissue oxygenation is difficult ...

journal_title：Vox sanguinis

authors： Raat NJ,Ince C

更新日期：2007-07-01 00:00:00

abstract：:A new therapeutic plasma exchange device developed by Sarns Inc./3M was evaluated in plasmapheresis of 20 healthy volunteers and in a multicenter clinical study of therapeutic plasma exchange that included 49 patients. Safety and efficacy of plasma separation from whole blood were assessed for a module that contains D...

journal_title：Vox sanguinis

authors： Kurtz SR,Carey PM,McGill M,Pineda AA,Zaroulis CG,Case MT

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:For some unknown reason humans may 'spontaneously' produce high amounts of neutralizing autoantibodies to a number of growth factors and cytokines. Reaching a certain high level the antibodies render the person cytokine deficient, mostly without overt clinical manifestations. The autoantibodies in question a...

journal_title：Vox sanguinis

authors： Hansen MB,Galle P,Salomo M,Svenson M,Dickmeiss E,Gimsing P

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The low-prevalence Rh antigen, JAL, was named after the index case, Mr. J. Allen. Based on reactivity of seven multi-specific sera with his RBCs, it was apparent that they express at least one additional low-prevalence antigen. The purpose of this study was to investigate the other low-prevalence antigen(s) ...

journal_title：Vox sanguinis

authors： Hue-Roye K,Reid ME,Westhoff CM,Lomas-Francis C

更新日期：2011-07-01 00:00:00

abstract：:A major drawback in the use of platelet transfusions is the development of platelet refractoriness that is usually caused by alloimmunization provoked by leukocytes present in the blood products. We evaluated the development of alloimmunization both by serological demonstration of HLA antibodies and by clinical demons...

journal_title：Vox sanguinis

authors： Saarinen UM,Koskimies S,Myllylä G

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Early prediction of massive transfusion (MT) post-trauma may reduce mortality by earlier delivery of blood products. A clinical prediction tool (PWH score) for this purpose was developed at the Prince of Wales Hospital, Hong Kong. The aims of this study were to apply this tool to major trauma ...

journal_title：Vox sanguinis

authors： Mitra B,Rainer TH,Cameron PA

更新日期：2012-05-01 00:00:00

abstract：:Alanine aminotransferase (ALT), gamma-glutamyl-transferase and hepatitis B core antibodies were evaluated as donor markers in a prospective study of 685 open-heart surgery patients. Of these three surrogate markers, only an ALT level greater than or equal to 2 SD above the log mean had a significant association with r...

journal_title：Vox sanguinis

authors： Ebeling F

更新日期：1991-01-01 00:00:00

abstract：:The stabilization of human immunoglobulin (IgG) by chemically modified gelatins (Haemaccel and Gelofusine) was investigated. The gelatins prevented IgG from aggregation induced by exposure to interfaces and lyophilization. The stabilization effects of the gelatins were significantly larger than those of amino acids or...

journal_title：Vox sanguinis

authors： Tomono T,Ikeda K,Suzuki T

更新日期：1986-01-01 00:00:00

abstract：:Alpha1-Acid glycoprotein (orosomucoid) was prepared from a byproduct of the ethanol plasma fractionation by means of ion-exchange procedures. Immunoelectrophoresis suggested a high degree of purity; the purified protein contained 13.5% sialic acid and 17.8% hexose. The alpha1-acid glycoprotein was modified by removal ...

journal_title：Vox sanguinis

authors： van Rijk PP,Heinsius HL,van den Hamer CJ

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In Canada, transfusion transmission risk of Human T-cell lymphotropic virus -I/II (HTLV) is addressed by universal leucoreduction and universal antibody testing. We aimed to estimate the risk with the current policy, if testing only first-time donors and if testing were stopped. MATERIALS AND...

journal_title：Vox sanguinis

authors： O'Brien SF,Yi QL,Goldman M,Grégoire Y,Delage G

更新日期：2018-11-01 00:00:00

abstract：:Direct immunofluorescent staining of 31 specimens of platelets obtained from 13 cases of idiopathic thrombocytopenic purpura (ITP) revealed positive staining on the surface of platelets for both immunoglobulins (Igs) and human B1C globulin in 9 specimens, for only Igs in 1 specimen and for human B1C alone in 5 specime...

journal_title：Vox sanguinis

authors： Boonpucknavig S,Vuttivirojana O,Srichaikul T

更新日期：1979-01-01 00:00:00

abstract：:The effect of gamma irradiation on HIV and plasma coagulation factors F VIII:C, F VIII:vWF and FIX was studied. Donor plasma was harvested from single donations, frozen and irradiated in the frozen state at target doses from 0 to 40 kGy (0-4 mRad). HIV was inoculated into human plasma and irradiated in a similar manne...

journal_title：Vox sanguinis

authors： Kitchen AD,Mann GF,Harrison JF,Zuckerman AJ

更新日期：1989-01-01 00:00:00

abstract：:The mechanism of CD4+ lymphocyte depletion, which is the main immunological feature in HIV-infected patients, is unclear. We investigated whether gp120-immunoglobulin-complement complexes on the surface of CD4+ cells might be involved in the elimination of CD4+ lymphocytes. The results obtained in 63 HIV-infected pati...

journal_title：Vox sanguinis

authors： Daniel V,Süsal C,Prodeus AP,Weimer R,Zimmermann R,Huth-Kühne A,Opelz G

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There is increasing interest in the development of rapid and reliable techniques for human platelet alloantigen (HPA) typing. This study investigates the reliability of flow cytometry for large-scale immunophenotyping of platelet alloantigens. MATERIALS AND METHODS:We used flow cytometry and ...

journal_title：Vox sanguinis

authors： Tazzari PL,Cirillo D,Bontadini A,Ricci F,Masi R,Conte R

更新日期：1998-01-01 00:00:00

abstract：:The proteins and sodium in human source blood plasma are segregated and concentrated on freezing, particularly in plasma that is frozen slowly in a large container. The temperature and the concentration gradients at the freezing front induce a convection in the liquid phase and thus play the primary role in the segreg...

journal_title：Vox sanguinis

authors： Chang CE

更新日期：1983-01-01 00:00:00

abstract：:Forty-six subjects (44 HIV antibody-positive) with some degree of immune deficiency (at least TH/TS ratio below 1) were randomly distributed into 4 treatment groups. Each group was assigned to 1 of 4 products to be used exclusively for a 1-year period: 1 concentrate was of intermediate purity and not heat-treated, and...

journal_title：Vox sanguinis

authors： Allain JP,Frommel D,Bosser C,Gazengel C,Larrieu MJ,Sultan Y

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Necrotizing enterocolitis (NEC) is a common and often severe gastrointestinal emergency in newborn infants. While usually affecting (very) premature infants, an association between NEC and haemolytic disease of the foetus and newborn (HDFN) has been suggested. HDFN may be an additional risk fa...

journal_title：Vox sanguinis

authors： Ree IMC,de Grauw AM,Bekker V,de Haas M,Te Pas AB,Oepkes D,Middeldorp AJM,Lopriore E

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:B subgroups are rare and the genetic analysis reported to date has been limited. MATERIALS AND METHODS:Serological and molecular investigations were performed in blood from a B-subgroup donor. RESULTS:Red cells did not react with anti-B and anti-AB reagents. However, cells absorbed anti-B. R...

journal_title：Vox sanguinis

authors： Sousa N,Anicchino-Bizzacchi JM,Leite EM,Locatelli MF,Albuquerque D,Costa FF,Barjas-Castro ML

更新日期：2005-01-01 00:00:00

abstract：:The polymorphism of the second component of human complement was studied by means of isoelectric focusing in polyacrylamide gels with subsequent complement-dependent lysis of sensitized sheep erythrocytes in an agarose overlay containing C2-deficient or normal human serum. In a material of 289 unrelated individuals th...

journal_title：Vox sanguinis

authors： Dewald G,Rittner C

更新日期：1979-01-01 00:00:00

abstract：:The storage of fresh frozen plasma (FFP) for short periods at -20 degrees C for 6 weeks, -30 degrees C for 12 weeks, or -40 degrees C for 12 weeks, did not result in significant deterioration in factor VIII: coagulant (factor VIII:C) activity in the primary packs. In studies examining whether plasma segments could be ...

journal_title：Vox sanguinis

authors： Ofosu FA,Blajchman MA,Kaegi A,Turc JM

更新日期：1985-01-01 00:00:00

abstract：:Quality management is an ongoing development resulting in consistency products and services and ever increasing customer satisfaction. The ultimum is Total Quality Management. Quality systems and quality management in transfusion medicine have gained considerable attention since the outbreak of the AIDS epidemic. Wher...

journal_title：Vox sanguinis

authors： Smit-Sibinga CT

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Weak D phenotypes with very low antigen densities and DEL phenotype may not be detected in RhD typing routine and could be typed as D-negative, leading to D alloimmunization of D-negative recipients. The present study aimed to investigate the presence of RHD-positive genotypes in blood donors ...

journal_title：Vox sanguinis

authors： de Paula Vendrame TA,Prisco Arnoni C,Guilhem Muniz J,de Medeiros Person R,Pereira Cortez AJ,Roche Moreira Latini F,Castilho L

更新日期：2019-11-01 00:00:00

abstract：:A simple method, based on ethanol fractionation, for the preparation of highly purified human serum albumin with a higher yield than that of the conventional ethanol procedures is described. It consists of two purification steps, namely, precipitation of most of the other plasma proteins from a 3-fold diluted plasma w...

journal_title：Vox sanguinis

authors： Hao Y

更新日期：1979-01-01 00:00:00

abstract：:To elucidate the possible influence of previous blood transfusion on immune functions, the transfusion history of 153 patients admitted to hospital for elective colorectal surgery was correlated with lymphocyte subsets and natural killer (NK) cell function. The subsets determined were CD2, CD3, CD4, CD8, CD16, CD20, C...

journal_title：Vox sanguinis

authors： Mathiesen O,Lund L,Brodthagen U,Gandrup P,Grunnet N,Balslev I,Jersild C

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The results of quality monitoring leucocyte counts were analysed nationally for the first 2 years of universal leucocyte depletion (LD), spanning the time-period before and after standardization of the counting and LD methods. The objectives were twofold: first to determine whether the impleme...

journal_title：Vox sanguinis

authors： Beckman N,Cardigan R,Wallington T,Williamson LM

更新日期：2002-08-01 00:00:00

abstract：:Phenotype studies of ABO blood groups in most Amerindian populations revealed the exclusive presence of group O. Since group O is the result of the absence of glycosyltransferase activity, its molecular bases may be heterogeneous. We carried out ABO blood group genotyping by analysis of DNA of 30 Indians from 2 Amazon...

journal_title：Vox sanguinis

authors： Franco RF,Simões BP,Guerreiro JF,Santos SE,Zago MA

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Leucocyte-derived cytokines accumulate in stored whole blood. Pre-storage leucocyte depletion has reduced cytokine levels and, consequently, febrile non-haemolytic transfusion reactions. As leucocyte filtration and component separation can be performed until 24 h after donation, we hypothesize...

journal_title：Vox sanguinis

authors： Chudziak D,Sireis W,Pfeiffer HU,Henschler R,Seifried E,Bönig H

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The para-Bombay phenotype (also known as H-deficient secretor) is characterized by a lack of ABH antigens on red cells, but ABH substances are found in saliva. Molecular genetic analysis was performed for five Chinese individuals serologically typed as para-Bombay. MATERIALS AND METHODS:ABO g...

journal_title：Vox sanguinis

authors： Yip SP,Chee KY,Chan PY,Chow EY,Wong HF

更新日期：2002-10-01 00:00:00

abstract：:A pilot study for large-scale automated plasmapheresis using the Haemonetics Model 50 machine was undertaken in the Yorkshire Region of the United Kingdom to determine the viability of such a programme for national self-sufficiency in fresh plasma procurement for factor VIII concentrate production. The study was desig...

journal_title：Vox sanguinis

authors： Robinson AE,Penny AF,Smith J,Tovey DL

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Repeated isometric muscle tension (applied tension) during blood donation reduces vasovagal symptoms in many donors. Experiencing vasovagal symptoms has been found to reduce blood donor return. However, does practicing applied tension improve blood donor return? Follow-up results from a random...

journal_title：Vox sanguinis

authors： Ditto B,Gilchrist PT,Holly CD,Dubuc S,Delage G,France CR

更新日期：2013-11-01 00:00:00