Pulmonary complications during granulocyte transfusions: incidence and clinical features.

Abstract:

:The use of granulocyte transfusions in profoundly neutropenic patients has increased markedly in recent years. Whenever a pulmonary infiltrate develops during the course of these transfusions, the question arises as to what role the transfusions are playing and whether the transfusions should be discontinued to prevent pulmonary deterioration. We have analyzed our recent experience of 593 granulocyte transfusions in 93 patients. 18 patients (19%) developed respiratory compromise or pulmonary infiltrates at some time during the course of granulocyte transfusion. 6 of the 18 cases were reactions to the granulocytes while the remainder were due to fluid overload or other causes. The risk of pulmonary complications did not correlate with the development of cytotoxic leukocyte antibodies, length of transfusion, or concomitant use of Amphotericin. They appeared to be more common in patients with active sepsis. Acute life-threatening pulmonary reactions were rare. Patients receiving granulocyte transfusions should be monitored carefully for pulmonary infiltrates, but other cases should be sought before the transfusions are discontinued.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Karp DD,Ervin TJ,Tuttle S,Gorgone BC,Lavin P,Yunis EJ

subject

Has Abstract

pub_date

1982-02-01 00:00:00

pages

57-61

issue

2

eissn

0042-9007

issn

1423-0410

journal_volume

42

pub_type

杂志文章
  • Inactivation of hepatitis A virus by pasteurization and elimination of picornaviruses during manufacture of factor VIII concentrate.

    abstract::Hepatitis A virus (HAV) infections have been reported among hemophiliacs who received factor VIII concentrates which had been purified by ion-exchange chromatography and treated by the solvent detergent (SD) method. Since the virus inactivation procedure of our manufacturing process is heat treatment of the stabilized...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:

    authors: Hilfenhaus J,Nowak T

    更新日期:1994-01-01 00:00:00

  • Syphilis serology in blood donors: a possible surrogate marker for human immunodeficiency virus risk.

    abstract::We report a preliminary study on whether syphilis serology might be reactive in some blood donors at risk for human immunodeficiency virus (HIV) infection. We retrospectively analyzed voluntary blood donations with reactive Treponema pallidum antibody (TPA) tests according to the type of donation, the presence of othe...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1991.tb00895.x

    authors: Ramsey G,Soltis F,Bowman R,McNamee J,Hahn LF,Dixon BW

    更新日期:1991-01-01 00:00:00

  • Blood transfusion in preterm infants improves intestinal tissue oxygenation without alteration in blood flow.

    abstract:BACKGROUND AND OBJECTIVE:The objective of the study was to investigate the splanchnic blood flow velocity and oximetry response to blood transfusion in preterm infants according to postnatal age. MATERIALS AND METHODS:Preterm infants receiving blood transfusion were recruited to three groups: 1-7 (group 1; n = 20), 8-...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12436

    authors: Banerjee J,Leung TS,Aladangady N

    更新日期:2016-11-01 00:00:00

  • Editorial: Red cell ageing and death.

    abstract::To obtain red cell populations of increasing mean age erythropoiesis was arrested through continuous actinomycin treatment or maintained transfusion polycythemia in mice and rats respectively. The parameters studied included cell indices, enzyme activities and rheological characteristics. Further, the life-span of age...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1976.tb02809.x

    authors: Ganzoni AM,Barras JP,Marti HR

    更新日期:1976-01-01 00:00:00

  • The effect of previous blood transfusion on lymphocyte subsets and natural killer cell function in patients with colorectal cancer.

    abstract::To elucidate the possible influence of previous blood transfusion on immune functions, the transfusion history of 153 patients admitted to hospital for elective colorectal surgery was correlated with lymphocyte subsets and natural killer (NK) cell function. The subsets determined were CD2, CD3, CD4, CD8, CD16, CD20, C...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1994.tb05035.x

    authors: Mathiesen O,Lund L,Brodthagen U,Gandrup P,Grunnet N,Balslev I,Jersild C

    更新日期:1994-01-01 00:00:00

  • Quantification by ELISA of erythrocyte-bound C3 fragments expressing C3d and/or C3c epitopes in patients with factor I deficiency and with autoimmune diseases.

    abstract::A sensitive ELISA assay for quantifying erythrocyte (E) bound C3 fragments was developed. The assay employs a double-antibody sandwich technique, using polyclonal anti-C3d or anti-C3c antibodies to quantify C3 fragments, expressing C3d and/or C3c epitopes in washed, detergent-solubilized E. The assay detected 50-120 m...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1989.tb02039.x

    authors: Møller Rasmussen J,Jepsen HH,Teisner B,Holmskov-Nielsen U,Rasmussen GG,Svehag SE

    更新日期:1989-01-01 00:00:00

  • Efficiency of leukocyte removal by filters made of superfine glass fiber membranes.

    abstract:BACKGROUND AND OBJECTIVES:To demonstrate the application of leukocyte removal filters made of a new type of filter material - superfine glass fiber - for depleting leukocytes in SAGM red cell suspensions and preventing nonhemolytic transfusion reactions. MATERIALS AND METHODS:The extent of leukocyte depletion and red ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1159/000031015

    authors: Zou Y,Sun Q,Li A,Yao F,Hu Z,Li Z L,Ma W

    更新日期:1999-01-01 00:00:00

  • Transmission of parasites and bacteria by blood components.

    abstract:BACKGROUND AND OBJECTIVES:Although most attention has been paid to viral infections as a complication of transfusion, some parasitic infections are readily transmissible and generate a heavy burden of disease, particularly in the developing world. Additionally, bacterial infection as a result of transfusion is the most...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:

    authors: Dodd RY

    更新日期:2000-01-01 00:00:00

  • Red blood cell utilization and transfusion triggers in patients diagnosed with chronic lymphocytic leukaemia in Iceland 2003-2016.

    abstract:BACKGROUND AND OBJECTIVES:Revised Icelandic guidelines proposed a restrictive haemoglobin (Hb) threshold of 70 g/l for red blood cell (RBC) transfusions in general, but 100 g/l for malignancies/bone marrow suppression. Chronic lymphocytic leukaemia (CLL) is frequently complicated by anaemia. The objective was to invest...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12775

    authors: Thorvaldsson HH,Vidarsson B,Sveinsdottir SV,Olafsson GB,Halldorsdottir AM

    更新日期:2019-07-01 00:00:00

  • In vivo recovery and survival of red cells after photodynamic treatment with thiopyrylium and red light using a canine model.

    abstract::Recently, we have shown that thiopyrylium has robust inactivation capabilities against a broad spectrum of pathogens in the human red blood cell (RBC) suspensions while retaining key RBC in vitro properties. The 24-h recovery and survival of canine red cells were measured upon autologus reinfusion of control and photo...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2006.00864.x

    authors: Skripchenko A,Balch A,Mackin A,Wagner SJ

    更新日期:2007-02-01 00:00:00

  • Resuscitation fluids.

    abstract:BACKGROUND AND OBJECTIVES:The aim of this review was to summarize the properties of the commonly available resuscitation fluids and highlight where knowledge of the characteristics of individual fluids might guide their use in clinical practice. Some of the current controversies surrounding resuscitation fluids are als...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1046/j.1423-0410.2002.00123.x

    authors: Grocott MP,Hamilton MA

    更新日期:2002-01-01 00:00:00

  • IgG subclass deficiencies.

    abstract::IgG subclasses differ not only in their biochemical and biologic properties, but also in their occurrence as selective deficiencies, alone and in combination. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infect...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1986.tb02008.x

    authors: Hanson LA,Björkander J,Robbins JB,Schneerson R,Söderström R,Söderström T

    更新日期:1986-01-01 00:00:00

  • A comparison of in vitro tests for predicting the severity of haemolytic disease of the fetus and newborn.

    abstract::Haemolytic disease of the newborn (HDN) is characterized by the presence of IgG antibodies in the maternal circulation which cause haemolysis in the fetus by crossing the placenta and sensitizing red cells for destruction by macrophages in the fetal spleen. Numerous serological, quantitative and cellular assays have b...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1423-0410.1998.tb05445.x

    authors: Hadley AG

    更新日期:1998-01-01 00:00:00

  • The D antigen characteristic of RoHar is a partial D antigen.

    abstract::The results of testing RoHarr cells with panels of monoclonal anti-D suggest that the D antigen (referred to as DHar) encoded by the haplotype (D)c(e) Rh33 is a partial D antigen. IgM monoclonal anti-D are more efficient than IgG monoclonal anti-D in detecting DHar.DHar expresses some but not all of both epD5 and epD6...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1996.tb01317.x

    authors: Wallace M,Lomas-Francis C,Tippett P

    更新日期:1996-01-01 00:00:00

  • Collaborative study to establish a replacement World Health Organization International Standard for parvovirus B19 DNA nucleic acid amplification technology (NAT)-based assays.

    abstract:BACKGROUND AND OBJECTIVES:The aim of the study was to replace the 1(st) World Health Organization International Standard for parvovirus B19 DNA for nucleic acid amplification technique (NAT)-based assays (code 99/800). Two lyophilized preparations (coded 99/800 and 99/802) had been evaluated in the original collaborati...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1423-0410.2009.01288.x

    authors: Baylis SA,Chudy M,Blümel J,Pisani G,Candotti D,José M,Heath AB

    更新日期:2010-04-01 00:00:00

  • Effect of periodate oxidation on specific activities and carbohydrate components of human blood group N- and M-specific glycoproteins and glycopeptides.

    abstract::Mild as well as strong periodate oxidation of isolated erythrocyte N and M glycoproteins and glycopeptides gave extensive to complete destruction of N-specificities as measured with Vicia graminea extracts and of N- as well as M- activities determined with all but 1 of 8 animal anti-N and 13 anti-M sera. Results with ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1978.tb02931.x

    authors: Springer GF,Yang HJ

    更新日期:1978-01-01 00:00:00

  • Large-scale HCV RNA screening in first-time blood donors: the first step towards genomic screening of blood donations. HCV RNA Screening Study Group.

    abstract:BACKGROUND AND OBJECTIVES:Individual genomic screening for viruses in blood donations is becoming increasingly pressing as an alternative to pool testing to improve the safety of the blood supply. MATERIALS AND METHODS:To determine the feasibility and, possibly, efficacy of genomic screening for hepatitis C virus (HCV...

    journal_title:Vox sanguinis

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1159/000031041

    authors: Petrik J,Hewitt P,Barbara J,Allain J

    更新日期:1999-01-01 00:00:00

  • Interdiction of a blood donation containing varicella-zoster virus by donor self-report of chickenpox.

    abstract::Nowadays, risk of transfusion-transmitted infection has been substantially minimized by stringent donor eligibility screening and infectious disease testing. However, we report an interdiction of a blood donation containing varicella-zoster virus (VZV) by donor self-reporting of chickenpox. The donor developed varicel...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2012.01655.x

    authors: Chan HM,Ho PL,Chan KH,Lin CK,Lee CK

    更新日期:2013-04-01 00:00:00

  • Results of a multicentre clinical trial of the solid-phase enzyme immunoassay for hepatitis B surface antigen.

    abstract::The results obtained in a multicentre clinical trial of an enzyme immunoassay (EIA) method for hepatitis B surface antigen (HBsAg) (65,451 sera tested) have demonstrated that this new test has a significantly higher sensitivity than a reversed haemagglutination test (rHA). In a part of the trial, EIA was also compared...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1978.tb02902.x

    authors: Kacaki J,Wolters G,Kuijpers L,Stulemeyer S

    更新日期:1978-07-01 00:00:00

  • Detection of platelet-bound and serum antibodies in autoimmune thrombocytopenia by enzyme-linked assay.

    abstract::Platelet antibodies were looked for in 47 patients with autoimmune thrombocytopenia using a modification of the enzyme-linked assay previously described. Surface-bound antibodies measured as increased platelet-associated IgG were found in 32 (68%) of the patients. After incubation in test sera, the platelet-associated...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1981.tb01054.x

    authors: Hegde UM,Bowes A,Powell DK,Joyner MV

    更新日期:1981-11-01 00:00:00

  • Plasmodium falciparum malaria and the immunogenetics of ABO, HLA, and CD36 (platelet glycoprotein IV).

    abstract::Plasmodium falciparum malaria has long been a killer of the young, and has selected for polymorphisms affecting not only erythrocytes, but the immunogenetics of three histocompatibility systems: ABO, human leukocyte antigen (HLA), and CD36. The ABO system is important because the original allele, encoding glycosylatio...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1423-0410.2010.01429.x

    authors: Cserti-Gazdewich CM,Mayr WR,Dzik WH

    更新日期:2011-01-01 00:00:00

  • A radial immunodiffusion method for the measurement of rat fibrinogen and fibrin degradation products.

    abstract::The present report describes a technique for the production of monospecific rabbit antiserum to rat fibrinogen and its use in a quantitative radial immunodiffusion assay for measurement of rat fibrinogen and fibrin degradation products. It is a suitable technique for measurement of these parameters in small samples wh...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1979.tb04400.x

    authors: Kaplan JE,Blumenstock FA,Saba TM

    更新日期:1979-01-01 00:00:00

  • An autoantibody with activity dependent on red cell age in the serum of a patient with autoimmune haemolytic anaemia and a negative direct antiglobulin test.

    abstract::A red cell IgM autoantibody with anti-e specificity was identified in the serum of a rhesus-negative (rr) patient presenting with haemolytic anaemia and a negative direct antiglobulin test. The autoantibody strongly agglutinated normal allogeneic rhesus-negative (rr) red cells in saline at 37 degrees C but had only we...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1987.tb02993.x

    authors: Herron R,Clark M,Smith DS

    更新日期:1987-01-01 00:00:00

  • Direct comparison of three residual risk models for hepatitis B virus window period infections using updated input parameters.

    abstract:BACKGROUND AND OBJECTIVES:Comparison of two models for estimating residual transfusion transmission risk by NAT screened window period (WP) donations in South African repeat donors gave identical results for HIV but not for HBV. In order to understand discrepant HBV modelling outcomes, the values of input parameters in...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/vox.12889

    authors: Lelie N,Vermeulen M,van Drimmelen H,Coleman C,Bruhn R,Reddy R,Busch M,Kleinman S

    更新日期:2020-04-01 00:00:00

  • Lack of linkage between hereditary angioedema and the A and B loci of the HLA system.

    abstract::A large 81 member, four-generation black family with hereditary angioedema is reported with regards to its clinical course and the association with the histocompatibility system. No mortality was seen related directly to the disease. Assuming that this trait is autosomal dominant it appeared to have no linkage with th...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1978.tb02911.x

    authors: Blumenthal MN,Dalmasso AP,Roitman B,Kelly J,Noreen H,Emmy L,Mendell NR,Yunis EJ

    更新日期:1978-09-01 00:00:00

  • White blood cell fragments in platelet concentrates prepared by the platelet-rich plasma or buffy-coat methods.

    abstract:BACKGROUND AND OBJECTIVES:White blood cell (WBC) fragments in platelet concentrates (PCs) may induce allo-immunization in the recipient. MATERIALS AND METHODS:As the level of WBC fragments can differ between PCs produced using different methods, we compared PCs prepared by using the buffy-coat method (BC-PCs) in plasm...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2005.00634.x

    authors: Dijkstra-Tiekstra MJ,van der Schoot CE,Pietersz RN,Reesink HW

    更新日期:2005-05-01 00:00:00

  • White-blood-cell-containing allogeneic blood transfusion, postoperative infection and mortality: a meta-analysis of observational 'before-and-after' studies.

    abstract:BACKGROUND AND OBJECTIVES:An association of white blood cell (WBC) reduction with decreased mortality was reported by one observational, before-and-after study. A meta-analysis was undertaken to examine whether this finding is supported by all the evidence currently available from before-and-after studies, and whether ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,meta分析

    doi:10.1111/j.0042-9007.2004.00394.x

    authors: Vamvakas EC

    更新日期:2004-02-01 00:00:00

  • Simulation analysis of platelet production and inventory management.

    abstract::To maximize the availability of platelet concentrates (PC) and minimize their outdate, competing criteria, a computer simulation model of platelet production and distribution was developed. Based on 2 years of actual platelet orders placed with a regional blood center, the simulation program generated daily platelet o...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1983.tb04100.x

    authors: Katz AJ,Carter CW,Saxton P,Blutt J,Kakaiya RM

    更新日期:1983-01-01 00:00:00

  • Peroxidative events in stored platelet concentrates.

    abstract::Changes in metabolic and functional activity of platelets stored as platelet concentrates in plastic bags highly permeable to gases were investigated. The following parameters were measured daily: pH, pO2, pCO2, HCO3, glucose, lactic acid, lactic dehydrogenase, cellular ATP and platelet aggregation induced by differen...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1989.tb03043.x

    authors: Fagiolo E,Lippa S,Mores N,Oradei A,Aureli V

    更新日期:1989-01-01 00:00:00

  • A new platelet-specific alloantigen Bra. Report of 4 cases with neonatal alloimmune thrombocytopenia.

    abstract::Sera obtained from 4 mothers of children with neonatal alloimmune thrombocytopenia contained a platelet-specific alloantibody, anti-Bra, which defined an antigen apparently different from all known platelet alloantigens. All 4 fathers were Bra positive, whereas all mothers were Bra negative. The minimal postnatal valu...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1988.tb01625.x

    authors: Kiefel V,Santoso S,Katzmann B,Mueller-Eckhardt C

    更新日期:1988-01-01 00:00:00