Results of a multicentre clinical trial of the solid-phase enzyme immunoassay for hepatitis B surface antigen.

Abstract:

:The results obtained in a multicentre clinical trial of an enzyme immunoassay (EIA) method for hepatitis B surface antigen (HBsAg) (65,451 sera tested) have demonstrated that this new test has a significantly higher sensitivity than a reversed haemagglutination test (rHA). In a part of the trial, EIA was also compared with radioimmunoassay (RIA). Only a small number of discrepant results was obtained with these two tests, indicating similar sensitivities. No definite conclusion about a difference in sensitivities could be drawn from these results. Although the specificity of the EIA screening test is lower than that of rHA and RIA, the mean percentage of false positives was 2.2% of the total number of donor samples screened. Presumptive positives in EIA were subjected to a confirmatory test based on neutralization with human antibodies to HBsAg. After elimination of false positives in EIA screening, there was excellent agreement between EIA and RIA results.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Kacaki J,Wolters G,Kuijpers L,Stulemeyer S

doi

10.1111/j.1423-0410.1978.tb02902.x

subject

Has Abstract

pub_date

1978-07-01 00:00:00

pages

65-74

issue

1-2

eissn

0042-9007

issn

1423-0410

journal_volume

35

pub_type

杂志文章
  • Opsonic and complement-dependent bactericidal activities of various immunoglobulin preparations for intravenous use.

    abstract::Some effector functions of various immunoglobulin (IgG) preparations have been compared. Tests for opsonic activity were performed in vitro with human peripheral blood leukocytes and in vivo with mice. The augmentation effects on luminol-dependent chemiluminescence were investigated with human leukocytes. The compleme...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1986.tb01968.x

    authors: Yasuda H,Yajima T,Tanii T,Ashiba T,Iwata M

    更新日期:1986-01-01 00:00:00

  • A method for estimating the residual risk of transfusion-transmitted HBV infection associated with occult hepatitis B virus infection in a donor population without universal anti-HBc screening.

    abstract:BACKGROUND AND OBJECTIVES:This report describes a method for estimating the risk of transfusion-transmitted HBV infection attributable to blood components from donors with occult hepatitis B virus infection (OBI) applicable where universal anti-HBc screening is not performed. MATERIALS AND METHODS:In the context of pa...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12060

    authors: Seed CR,Kiely P

    更新日期:2013-11-01 00:00:00

  • In vivo recovery and survival of red cells after photodynamic treatment with thiopyrylium and red light using a canine model.

    abstract::Recently, we have shown that thiopyrylium has robust inactivation capabilities against a broad spectrum of pathogens in the human red blood cell (RBC) suspensions while retaining key RBC in vitro properties. The 24-h recovery and survival of canine red cells were measured upon autologus reinfusion of control and photo...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2006.00864.x

    authors: Skripchenko A,Balch A,Mackin A,Wagner SJ

    更新日期:2007-02-01 00:00:00

  • Sexual risk behaviour and donor deferral in Europe.

    abstract::One of the most controversial policies in blood transfusion worldwide is the permanent deferral from donating blood of men with sexual contacts to other men (MSM). This policy was implemented for safety reasons as sex between men is known to be a high risk factor for acquiring severe infectious diseases transmissible ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12179

    authors: Offergeld R,Kamp C,Heiden M,Norda R,Behr-Gross ME

    更新日期:2014-11-01 00:00:00

  • Blood group ABH antigens on human cord red cells. Number of H antigenic sites and their distribution among different classes of membrane constituents.

    abstract::When the blood group H sites of cord erythrocytes obtained from newborn infants of groups O, A, B and AB were labelled specifically by incubation of the whole cells with the A1 gene dependent alpha-N-acetylgalactosaminyl transferase in the presence of UDP-N-acetyl [14C]-galactosamine, the incorporation of radioactivit...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1980.tb04497.x

    authors: Schenkel-Brunner H

    更新日期:1980-06-01 00:00:00

  • Accumulation of soluble inflammatory mediators between blood donation and pre-storage leucocyte depletion.

    abstract:BACKGROUND AND OBJECTIVES:Leucocyte-derived cytokines accumulate in stored whole blood. Pre-storage leucocyte depletion has reduced cytokine levels and, consequently, febrile non-haemolytic transfusion reactions. As leucocyte filtration and component separation can be performed until 24 h after donation, we hypothesize...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2008.01132.x

    authors: Chudziak D,Sireis W,Pfeiffer HU,Henschler R,Seifried E,Bönig H

    更新日期:2009-02-01 00:00:00

  • Children with AIDS.

    abstract::The etiologic agent for acquired immune deficiency syndrome (AIDS) has been identified as human T lymphotropic virus type III (HTLV-III). Its distinguishing characteristics and putative receptor, the T4 molecule, are discussed. The Western Blot method has been applied to assess the presence of antibody to HTLV-III in ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1986.tb02005.x

    authors: Pahwa S

    更新日期:1986-01-01 00:00:00

  • A novel mutation of the GATA site in the erythroid cell-specific regulatory element of the ABO gene in a blood donor with the Am B phenotype.

    abstract::The Am and Bm phenotypes are characterized by weak expression of the A or B antigens, respectively, by red blood cells with a normal expression by the saliva of secretors. Deletion of the regulatory element in the first intron of the ABO gene and disruption of the GATA motif in the element were found to be responsible...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12229

    authors: Oda A,Isa K,Ogasawara K,Kameyama K,Okuda K,Hirashima M,Ishii H,Kimura K,Matsukura H,Hirayama F,Kawa K

    更新日期:2015-05-01 00:00:00

  • In vitro phagocytosis of liquid-stored red blood cells requires serum and can be inhibited with fucoidan and dextran sulphate.

    abstract:BACKGROUND AND OBJECTIVES:Red-blood-cells (RBCs) undergo structural and metabolic changes with prolonged storage, which ultimately may decrease their survival after transfusion. Although the storage-induced damage to RBCs has been rather well described biochemically, little is known about the mechanisms underlying the ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12922

    authors: Hult A,Toss F,Malm C,Oldenborg PA

    更新日期:2020-11-01 00:00:00

  • Impact of tobacco smoking on platelet function in apheresis products in vitro.

    abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to analyse the platelet function, over a 5-day time-period, of apheresis-derived platelet concentrates obtained from smokers and non-smokers. MATERIALS AND METHODS:Smoker and non-smoker plateletpheresis products were investigated on days 1, 3 and 5 of storage. Recept...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.0042-9007.2004.00507.x

    authors: Scheinichen D,Heuft HG,Renken C,Jüttner B,Jaeger K,Schürholz T,Blasczyk R,Piepenbrock S,Elsner HA

    更新日期:2004-05-01 00:00:00

  • Patient-specific transfusion-related acute lung injury.

    abstract::Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-associated mortality. The inadvertent transfusion of neutrophil antibodies can cause pulmonary transfusion reactions and TRALI. However, not all patients transfused with neutrophil antibodies experience transfusion reactions. A 2...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2007.00982.x

    authors: Muniz M,Sheldon S,Schuller RM,Young NS,Klein HG,Leitman SF,Stroncek DF

    更新日期:2008-01-01 00:00:00

  • Di (2-ethylhexyl)phthalate content of plasma fractions prepared by low temperature ethanol (Cohn) fractionation.

    abstract::Plasma pools, prepared from time-expired blood stored in plastic packs, were analysed for DEHP content and levels ranging from 0.78 to 7.42 mh DEHP/100 ml plasma obtained. The DEHP content of the Cohn fractions prepared from such plasma pools was estimated. Only very low levels of DEHP were found in the four therapeut...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1975.tb00504.x

    authors: Gilbo CM,Coles NW

    更新日期:1975-01-01 00:00:00

  • Oversight and monitoring of blood safety in the United States.

    abstract::The US blood safety vigilance system is composed of a network of interwoven programs, now organized under a formal structure, with the Assistant Secretary of Health and DHHS Blood Safety Committee bearing overall responsibility. It takes advantage of the breadth of expertise and close collaborative relationship of tra...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1159/000031079

    authors: Busch M,Chamberland M,Epstein J,Kleinman S,Khabbaz R,Nemo G

    更新日期:1999-01-01 00:00:00

  • CD36 autoantibodies and thrombotic diathesis, thrombocytopenia and repeated early fetal losses.

    abstract:BACKGROUND AND OBJECTIVES:Autoantibodies to CD36, a platelet glycoprotein, have been found in patients with thrombotic thrombocytopenic purpura, and in those with lupus-like anticoagulant with thrombotic complications. MATERIALS AND METHODS:Conventional hematologic and laboratory methods were used. The patient was a p...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1046/j.1423-0410.1997.7310046.x

    authors: Borzini P,Riva M,Nembri P,Rossi E,Pagliaro P,Vergani P,Greppi P,Tantardini P

    更新日期:1997-01-01 00:00:00

  • Platelet storage media.

    abstract::Present platelet storage media often designated platelet additive solutions (PAS) basically contain acetate, citrate and phosphate and recently also potassium and magnesium. However, there seems to be an increasing interest in developing PASs that can be used also after further reduction of residual plasma content bel...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/vox.12172

    authors: Gulliksson H

    更新日期:2014-10-01 00:00:00

  • Molecular basis of Tn-polyagglutinability.

    abstract::Spectrophotometric and gas-liquid chromatographic analyses on the carbohydrate moiety of tryptic erythrocyte glycopeptides from persons with Tn-syndrome reveal a selective lowering of the galactose and sialic acid content, the degree being dependent on the percentage of polyagglutinable cells. Alkaline borohydride spe...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1975.tb00475.x

    authors: Dahr W,Uhlenbruck G,Gunson HH,Van Der Hart M

    更新日期:1975-01-01 00:00:00

  • Resuscitation fluids.

    abstract:BACKGROUND AND OBJECTIVES:The aim of this review was to summarize the properties of the commonly available resuscitation fluids and highlight where knowledge of the characteristics of individual fluids might guide their use in clinical practice. Some of the current controversies surrounding resuscitation fluids are als...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1046/j.1423-0410.2002.00123.x

    authors: Grocott MP,Hamilton MA

    更新日期:2002-01-01 00:00:00

  • Transmission of parasites and bacteria by blood components.

    abstract:BACKGROUND AND OBJECTIVES:Although most attention has been paid to viral infections as a complication of transfusion, some parasitic infections are readily transmissible and generate a heavy burden of disease, particularly in the developing world. Additionally, bacterial infection as a result of transfusion is the most...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:

    authors: Dodd RY

    更新日期:2000-01-01 00:00:00

  • The 'cherry buffy-coat syndrome', a cause of decreased platelet yield in platelet concentrates obtained from buffy-coats.

    abstract:BACKGROUND AND OBJECTIVES:A large number of European blood centres, including our own, use the buffy-coat method for platelet production. In this article we describe a previously unnoticed phenomenon shown by a proportion of buffy-coats, which display an unusually bright cherry colour and low platelet counts. MATERIAL...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1046/j.1423-0410.2001.00005.x

    authors: Rebulla P,Smacchia C,Greppi N,Porretti L,Lopa R,Cernuschi M,Sirchia G

    更新日期:2001-01-01 00:00:00

  • Diverse and novel RHD variants in Australian blood donors with a weak D phenotype: implication for transfusion management.

    abstract:BACKGROUND AND OBJECTIVES:Variant RHD genes associated with the weak D phenotype can result in complete or partial D-epitope expression on the red cell. This study examines the genetic classification in Australian blood donors with a weak D phenotype and correlates RHD variants associated with the weak D phenotype agai...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12488

    authors: McGowan EC,Lopez GH,Knauth CM,Liew YW,Condon JA,Ramadi L,Parsons K,Turner EM,Flower RL,Hyland CA

    更新日期:2017-04-01 00:00:00

  • Human alloantibodies detecting a red cell antigen apparently identical to MER2.

    abstract::Three examples of an antibody were found to be detecting a red cell polymorphism probably identical to MER2. The antibodies were made by Jews originating from India and living in Israel. Two of them were sibs and the third was unrelated. All 3 had kidney disease requiring renal dialysis and regular blood transfusion. ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1988.tb05085.x

    authors: Daniels GL,Levene C,Berrebi A,Schechter Y,Moulds M,Sela R,Poole J,Lacey P,Atkins CJ

    更新日期:1988-01-01 00:00:00

  • A new liquid, intravenous immunoglobulin product (IGIV 10%) highly purified by a state-of-the-art process.

    abstract:BACKGROUND AND OBJECTIVES:The ultimate goal was to generate an industrial-scale process suitable to produce a high-yield, safe and stable immunoglobulin G (IgG) preparation for intravenous administration, which is ready to use for customer convenience. This new liquid 10% IgG preparation (IGIV 10%) was compared to Gamm...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2006.00846.x

    authors: Teschner W,Butterweck HA,Auer W,Muchitsch EM,Weber A,Liu SL,Wah PS,Schwarz HP

    更新日期:2007-01-01 00:00:00

  • Serological characterization of murine monoclonal antibodies directed against acquired B red cells.

    abstract::Balb/c mice were immunized with acquired B red cells. Twelve clones specific for acquired B red cells were obtained from two fusions. A detailed investigation of three clones is reported here. These antibodies appear to be directed to the B-like epitope since they are inhibited by galactosamine and fail to react after...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1990.tb05017.x

    authors: Janvier D,Veaux S,Reviron M,Guignier F,Benbunan M

    更新日期:1990-01-01 00:00:00

  • Loss of phosphotyrosine phosphatase activity and changes in the tyrosine phosphorylation state of proteins after storage of sheep platelets in plasma or Seto solution at 4 degrees C.

    abstract:BACKGROUND AND OBJECTIVES:During platelet storage an array of deleterious changes occur, through mechanisms not fully understood, which impair platelet haemostasis. Transfused platelets should maintain the integrated networks of signalling pathways that regulate platelet activation and functionality. We hypothesized th...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1046/j.1423-0410.2001.00111.x

    authors: Hernández-Hernández A,Sánchez-Bernal C,Rodríguez MC,Gómez FP,Llanillo M,Sánchez-Yagüe J

    更新日期:2001-11-01 00:00:00

  • Lack of linkage between hereditary angioedema and the A and B loci of the HLA system.

    abstract::A large 81 member, four-generation black family with hereditary angioedema is reported with regards to its clinical course and the association with the histocompatibility system. No mortality was seen related directly to the disease. Assuming that this trait is autosomal dominant it appeared to have no linkage with th...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1978.tb02911.x

    authors: Blumenthal MN,Dalmasso AP,Roitman B,Kelly J,Noreen H,Emmy L,Mendell NR,Yunis EJ

    更新日期:1978-09-01 00:00:00

  • Alloimmunization against Iy, a low-frequency antigen on platelet glycoprotein Ib/IX as a cause of severe neonatal alloimmune thrombocytopenic purpura.

    abstract::Neonatal alloimmune thrombocytopenia (NAIT) is usually induced by platelet-specific antibodies against HPA-1a (Zwa) or HPA-5b (Bra). Recently, low-frequency alloantigens on the platelet glycoprotein (GP) IIb/IIIa complex have been discovered as a cause for NAIT. In this report, a new low-frequency platelet-specific al...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1995.tb02604.x

    authors: Kiefel V,Vicariot M,Giovangrandi Y,Kroll H,Böhringer M,Greinacher A,Breitfeld C,Santoso S,Mueller-Eckhardt C

    更新日期:1995-01-01 00:00:00

  • A single unit of transfused allogeneic blood increases postoperative infections.

    abstract::The aim of this prospective study was to evaluate if there was a statistical correlation between allogeneic blood transfusion and postoperative infections, and if this could have a dose-dependent pattern. The evaluation was based on multiple logistic and receiver operating characteristics (ROC) curve analyses. On hosp...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1046/j.1423-0410.1996.7130170.x

    authors: Vignali A,Braga M,Gianotti L,Radaelli G,Gentilini O,Russo A,Di Carlo V

    更新日期:1996-01-01 00:00:00

  • Serum IgE in polytransfused thalassemic patients.

    abstract::Serum IgE was determined by radioimmunoassay in 28 subjects affected by homozygous beta thalassemia (14 males and 14 females, aged 3-19 years, mean age 7 +/- 5.6 years). They were given transfusions with packed red cells and chelant therapy. Blood samples were taken just before a transfusion (basal value) and at 10-da...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1983.tb01931.x

    authors: La Rosa M,Pavone L,Musumeci S,Mollica F,Ronchetti R

    更新日期:1983-01-01 00:00:00

  • Use of Fab anti-IgG in phenotyping IgG-sensitised red cells.

    abstract::Previously described methods of phenotyping red cells sensitised with IgG using the indirect antiglobulin test required the dissociation of the coating protein. Based on an entirely different principle, Fab fragments of anti-human IgG (Fab anti-IgG) were used to block the antiglobulin binding sites on cell-bound IgG m...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1987.tb04939.x

    authors: Henry SM,Baird SJ,Woodfield DG

    更新日期:1987-01-01 00:00:00

  • Prothrombin complex concentrate for emergent reversal of warfarin: an international survey of hospital protocols.

    abstract::For emergent warfarin reversal, four-factor prothrombin complex concentrates (4FPCCs) are recommended by many international guidelines. We surveyed international clinical sites including members of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Most sites have emergent warfarin reversal protocol...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12539

    authors: Gorlin J,Kinney S,Fung MK,Tinmouth A,BEST Collaborative.

    更新日期:2017-08-01 00:00:00