Prothrombin complex concentrate for emergent reversal of warfarin: an international survey of hospital protocols.

abstract：:To elucidate the possible influence of previous blood transfusion on immune functions, the transfusion history of 153 patients admitted to hospital for elective colorectal surgery was correlated with lymphocyte subsets and natural killer (NK) cell function. The subsets determined were CD2, CD3, CD4, CD8, CD16, CD20, C...

journal_title：Vox sanguinis

authors： Mathiesen O,Lund L,Brodthagen U,Gandrup P,Grunnet N,Balslev I,Jersild C

更新日期：1994-01-01 00:00:00

abstract：:Early and regular blood transfusion therapy in patients with homozygous beta-thalassaemia decreases the complications of severe anaemia and prolongs survival. In the long term, however, the beneficial effects of transfusions are limited by the organ damage resulting from iron overload, a consequence of the body's limi...

journal_title：Vox sanguinis

authors： Prati D

更新日期：2000-01-01 00:00:00

abstract：:Inhibitor development represents the main complication in the treatment of haemophilia A. The risk of inhibitor formation is in part genetically determined by the type of the underlying factor VIII gene lesion but environmental factors may also play an important role. Due to the lack of efficiency of factor VIII in th...

journal_title：Vox sanguinis

authors： Brackmann HH,Schwaab R,Effenberger W,Hess L,Hanfland P,Oldenburg J

更新日期：2000-01-01 00:00:00

abstract：:Interest in immunogenetics originated from two streams: (a) histocompatibility in mouse and man, and (b) inheritance of specific immune responses in the guinea pig and mouse. In the mouse, there are genes associated with the major histocompatibility complex (MHC) which (i) code for antigens determining allograft respo...

journal_title：Vox sanguinis

authors： Mackay IR,Wittingham S,Tait B

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The German Armed Forces Blood Service in Koblenz supplies red blood cell concentrates (RBCs) to military and civilian institutions at home and to field hospitals during peacekeeping operations abroad. During long-distance transport, blood products can be exposed to extreme environmental condit...

journal_title：Vox sanguinis

authors： Klose T,Borchert HH,Pruss A,Roth WK,Bohnen HR,Putzker M

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Since July 1 1999, four laboratories in the Netherlands have been routinely screening plasma minipools for the release of labile blood components utilizing hepatitis C virus nucleic acid amplification technology (HCV NAT). This report describes the performance evaluation of the HCV NAT method ...

journal_title：Vox sanguinis

authors： Cuijpers HT,Molijn MH,Bos HJ,Peeters AP,van der Poel CL,Lelie PN

更新日期：2001-07-01 00:00:00

abstract：:Platelet concentrates (PCs), stored for 5 days in PL 2209, a new polyvinyl chloride (PVC) storage container plasticised with butyryl trihexyl citrate, were compared with those stored in PL 1240, a PVC platelet container plasticised with triethylhexyl trimellitate. In part 1 of the study, pooled platelet-rich plasma (P...

journal_title：Vox sanguinis

authors： Turner VS,Mitchell SG,Kang SK,Hawker RJ

更新日期：1995-01-01 00:00:00

abstract：:Monocyte-erythrocyte interaction in patients with autoimmune haemolytic anaemia (AIHA) was assessed by phagocytosis and rosette assays. In most patients, a relationship was observed between haemolysis and the phagocytosis of their own erythrocytes by allogenic peripheral monocytes. An evaluation of the number of immun...

journal_title：Vox sanguinis

authors： Zupańska B,Brojer E,Thomson EE,Merry AH,Seyfried H

更新日期：1987-01-01 00:00:00

abstract：:The effect of gamma irradiation on HIV and plasma coagulation factors F VIII:C, F VIII:vWF and FIX was studied. Donor plasma was harvested from single donations, frozen and irradiated in the frozen state at target doses from 0 to 40 kGy (0-4 mRad). HIV was inoculated into human plasma and irradiated in a similar manne...

journal_title：Vox sanguinis

authors： Kitchen AD,Mann GF,Harrison JF,Zuckerman AJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Weak ABO variants may escape tests using unlicensed sera. MATERIALS AND METHODS:Prior to transfusion, ABO grouping was performed using an automated system and in-house diluted sera, and manual and bedside test techniques. Genotyping and sequencing were performed using standard methods. RESUL...

journal_title：Vox sanguinis

authors： Pruss A,Heymann GA,Braun J,Kiesewetter HH,Salama A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The amino acid substitutions caused by ABO gene variants are usually predicted to impact the glycosyltransferase function. Here, the effect of an amino acid substitution in the vicinity of the catalytic active region of the B-glycosyltransferase was explored in vitro and in silico study, which is important f...

journal_title：Vox sanguinis

authors： Ying Y,Hong X,Xu X,Zhang J,He J,Zhu F,Xie X

更新日期：2020-12-16 00:00:00

abstract：:A mouse IgG1 monoclonal antibody (MAb) UMRh, was prepared by immunizing Balb/c mice with the Jurkat T cell acute lymphoblastic leukemia (T-ALL) cell line. The MAb UMRh is directed against a widely distributed Rh-related cell surface antigen, present on red blood cells (RBCs) expressing the more common Rh phenotypes. T...

journal_title：Vox sanguinis

authors： Poss MT,Swanson JL,Telen MJ,Lasky LC,Vallera DA

更新日期：1993-01-01 00:00:00

abstract：:Two preparations of fresh frozen plasma were studied. The plasma from CPDA-1 whole blood units was either frozen within 6 h (FFP-I) or 18-20 h (FFP-II) of phlebotomy. Average activity for factor VIII for FFP-I (n = 6) and FFP-II (n = 19) was 102% and 55%, respectively (p less than 0.01). Average activity for factor V ...

journal_title：Vox sanguinis

authors： Kakaiya RM,Morse EE,Panek S

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There are conflicting data regarding the therapeutic efficacy of platelets inactivated using amotosalen and ultraviolet A light. We have performed a meta-analysis to summarize the results of different randomized controlled trials (RCT). MATERIALS AND METHODS:Five RCTs reported through March 2...

journal_title：Vox sanguinis

authors： Cid J,Escolar G,Lozano M

更新日期：2012-11-01 00:00:00

abstract：:A number of parasitic diseases are known, or suspected to be transmitted by blood transfusion. Of greatest concern are malaria and Chagas' disease, but babesia, leishmania and toxoplasmosis also offer risk in particular locations or circumstances. Some of these parasites may be imported into non-endemic areas as a res...

journal_title：Vox sanguinis

authors： Dodd RY

更新日期：1998-01-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-associated mortality. The inadvertent transfusion of neutrophil antibodies can cause pulmonary transfusion reactions and TRALI. However, not all patients transfused with neutrophil antibodies experience transfusion reactions. A 2...

journal_title：Vox sanguinis

authors： Muniz M,Sheldon S,Schuller RM,Young NS,Klein HG,Leitman SF,Stroncek DF

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:ISO standards for blood bags do not adequately define and control the dimensions of blood bag transfer tubing. This lack of standardization presents potential difficulties when making sterile connections between the wide range of tubing that has evolved in the absence of such standards. We aim...

journal_title：Vox sanguinis

authors： Nightingale MJ,Lees B,Biset R,Mertens W

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The rationale for using topical platelet gel therapy is to provide the healing tissues with concentrated platelet-derived factors. Several systems are available to prepare platelet-rich plasma (PRP) and from these, the platelet gel. These systems produce two- to six-fold platelet and growth factor-enriched c...

journal_title：Vox sanguinis

authors： Mazzucco L,Balbo V,Cattana E,Guaschino R,Borzini P

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Since the first cases of acquired immunodeficiency syndrome in persons with haemophilia were reported in 1982, much has been written about the consequences of human immunodeficiency virus (HIV) contamination of the blood supply. Relatively little attention has been paid to similar hepatitis C virus (HCV) con...

journal_title：Vox sanguinis

authors： Angelotta C,McKoy JM,Fisher MJ,Buffie CG,Barfi K,Ramsey G,Frohlich L,Bennett CL

更新日期：2007-08-01 00:00:00

abstract：:The results of testing RoHarr cells with panels of monoclonal anti-D suggest that the D antigen (referred to as DHar) encoded by the haplotype (D)c(e) Rh33 is a partial D antigen. IgM monoclonal anti-D are more efficient than IgG monoclonal anti-D in detecting DHar.DHar expresses some but not all of both epD5 and epD6...

journal_title：Vox sanguinis

authors： Wallace M,Lomas-Francis C,Tippett P

更新日期：1996-01-01 00:00:00

abstract：:Alloimmune neonatal thrombocytopenia (ANT) may cause intracranial haemorrhage in utero as well as at delivery. Recent management has concentrated on attempts to minimise fetal thrombocytopenia and prevent its complications. This report describes further experience with the use of repeated intravascular transfusions of...

journal_title：Vox sanguinis

authors： Murphy MF,Pullon HW,Metcalfe P,Chapman JF,Jenkins E,Waters AH,Nicolaides KH,Mibashan RS

更新日期：1990-01-01 00:00:00

abstract：:The biochemical status of whole blood stored in containers fabricated of ethylene ethylacrylate (EEA) film was monitored at several times during 4 weeks of storage at 4 degrees C. Fifteen biochemical indicators were studied to reflect on erythrocyte integrity, cellular metabolism, plasma protein stability, and microag...

journal_title：Vox sanguinis

authors： Horowitz B,Rowe AW,Stryker MH,Van der Sande J,Waldman AA,Wong SC,Gass JD,Woods KR

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A patient transfused with two pooled platelet concentrates became breathless. Bilateral infiltrates were seen on chest X-ray. A diagnosis of transfusion-related acute lung injury (TRALI) was made. The patient received 100% oxygen and recovered after 5 days. MATERIALS AND METHODS:Antibody scre...

journal_title：Vox sanguinis

authors： Lucas G,Rogers S,Evans R,Hambley H,Win N

更新日期：2000-01-01 00:00:00

abstract：:A survey of the occurrence of lympho-agglutinins was carried out on seeds of 150 species of wild and cultivated plants. Potent agglutinins were detected in 17 extracts by employing lymphocytes of man, guinea pig, goat and sheep in the bioassay. Except for one species each of Mimosoideae, Euphorbiaceae and Clusiaceae, ...

journal_title：Vox sanguinis

authors： Sandhu RS,Kamboj SS,Reen RS,Arora JS

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There is increasing interest in the development of rapid and reliable techniques for human platelet alloantigen (HPA) typing. This study investigates the reliability of flow cytometry for large-scale immunophenotyping of platelet alloantigens. MATERIALS AND METHODS:We used flow cytometry and ...

journal_title：Vox sanguinis

authors： Tazzari PL,Cirillo D,Bontadini A,Ricci F,Masi R,Conte R

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Gene conversion events between GYPA and GYPB or GYPA and GYPE are facilitated by the close chromosomal proximity and high degree of sequence homology and can lead to the formation of GP hybrid genes. Discrepant results between blood group genotyping and haemagglutination in 22 random blood don...

journal_title：Vox sanguinis

authors： Polin H,Danzer M,Reiter A,Brisner M,Gaszner W,Weinberger J,Gabriel C

更新日期：2014-11-01 00:00:00

abstract：:Platelet concentrates (PC) prepared from pooled buffy coat (BC-PC) contain a variable number of leukocytes from different donors. We questioned whether storage of BC-PC can lead to a lymphocyte activation in the sense of a mixed lymphocyte reaction. BC-PC were prepared from four ABO-identical buffy coats and we undert...

journal_title：Vox sanguinis

authors： Klüter H,Müller-Steinhardt M,Danzer S,Wilhelm D,Kirchner H

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Inaccuracy of fingerstick haemoglobin compromises donor's health and losses blood donations. We evaluated the benefit of double haemoglobin screening with HemoCue. STUDY DESIGN AND METHODS:Blood donors underwent fingerstick screening by HemoCue and were driven for donation if capillary haemog...

journal_title：Vox sanguinis

authors： Gómez-Simón A,Plaza EM,Torregrosa JM,Ferrer-Marín F,Sánchez-Guiu I,Vicente V,Lozano ML,Rivera J

更新日期：2014-11-01 00:00:00

abstract：:Since its discovery, human plasminogen (PLG) polymorphism has received widespread acceptance in population genetics and forensic haematology. Due to the large number of variant alleles described, a PLG reference typing and Plasminogen Symposium was held, at which a nomenclature proposal was inaugurated. The technology...

journal_title：Vox sanguinis

authors： Skoda U,Bertrams J,Dykes D,Eiberg H,Hobart M,Hummel K,Kühnl P,Mauff G,Nakamura S,Nishimukai H

更新日期：1986-01-01 00:00:00

abstract：:Haemolytic disease of the newborn (HDN) is characterized by the presence of IgG antibodies in the maternal circulation which cause haemolysis in the fetus by crossing the placenta and sensitizing red cells for destruction by macrophages in the fetal spleen. Numerous serological, quantitative and cellular assays have b...

journal_title：Vox sanguinis

authors： Hadley AG

更新日期：1998-01-01 00:00:00