Abstract:
BACKGROUND AND OBJECTIVES:A patient transfused with two pooled platelet concentrates became breathless. Bilateral infiltrates were seen on chest X-ray. A diagnosis of transfusion-related acute lung injury (TRALI) was made. The patient received 100% oxygen and recovered after 5 days. MATERIALS AND METHODS:Antibody screening, cross-matching for granulocyte and lymphocyte antibodies and typing for granulocyte antigens was undertaken. RESULTS:The patient typed as HNA-1b/HNA-1b. Granulocyte and lymphocyte antibodies were not detected in the patient's serum or in any of the donor sera by cross-match. In antibody screening against typed panel granulocytes, complement-fixing anti-HNA-1a IgM antibodies were detected in the serum of one female donor. Two of the other donors who contributed to the pooled platelet concentrate containing the HNA-1a IgM antibodies typed as HNA-1a/HNA-1b. CONCLUSION:Anti-HNA-1a IgM antibodies may have formed immune complexes with white cell fragments or soluble FcgammaRIII from HNA-1a+ donors in the pooled platelet concentrate and initiated TRALI.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Lucas G,Rogers S,Evans R,Hambley H,Win Ndoi
10.1159/000031222subject
Has Abstractpub_date
2000-01-01 00:00:00pages
112-5issue
2eissn
0042-9007issn
1423-0410pii
31222journal_volume
79pub_type
杂志文章相关文献
VOX SANGUINIS文献大全abstract:BACKGROUND AND OBJECTIVES:Red-blood-cells (RBCs) undergo structural and metabolic changes with prolonged storage, which ultimately may decrease their survival after transfusion. Although the storage-induced damage to RBCs has been rather well described biochemically, little is known about the mechanisms underlying the ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12922
更新日期:2020-11-01 00:00:00
abstract::Anti-D levels in blood taken immediately postpartum from Rh-negative women who have been given antenatal Rh immune globulin and the anti-D levels in the cord blood of their babies were measured semiquantitatively by a low ionic polybrene Auto Analyzer technique. When both mother and baby were Rh-negative a comparison ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1982.tb00031.x
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:B subgroups are rare and the genetic analysis reported to date has been limited. MATERIALS AND METHODS:Serological and molecular investigations were performed in blood from a B-subgroup donor. RESULTS:Red cells did not react with anti-B and anti-AB reagents. However, cells absorbed anti-B. R...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.2005.00583.x
更新日期:2005-01-01 00:00:00
abstract::The commercial immune serum globulin (ISG) product is suitable for use in passive immunization only by intramuscular administration; intravenous use results in vasomotor side reactions. We report the functional characterization of a chemically modified ISG (MISG) that is essentially free of nonspecific complement-bind...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1981.tb00726.x
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Autoantibodies to CD36, a platelet glycoprotein, have been found in patients with thrombotic thrombocytopenic purpura, and in those with lupus-like anticoagulant with thrombotic complications. MATERIALS AND METHODS:Conventional hematologic and laboratory methods were used. The patient was a p...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1046/j.1423-0410.1997.7310046.x
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:There are conflicting data regarding the therapeutic efficacy of platelets inactivated using amotosalen and ultraviolet A light. We have performed a meta-analysis to summarize the results of different randomized controlled trials (RCT). MATERIALS AND METHODS:Five RCTs reported through March 2...
journal_title:Vox sanguinis
pub_type: 杂志文章,meta分析
doi:10.1111/j.1423-0410.2012.01614.x
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The results of quality monitoring leucocyte counts were analysed nationally for the first 2 years of universal leucocyte depletion (LD), spanning the time-period before and after standardization of the counting and LD methods. The objectives were twofold: first to determine whether the impleme...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1046/j.1423-0410.2002.00210.x
更新日期:2002-08-01 00:00:00
abstract::The results obtained in a multicentre clinical trial of an enzyme immunoassay (EIA) method for hepatitis B surface antigen (HBsAg) (65,451 sera tested) have demonstrated that this new test has a significantly higher sensitivity than a reversed haemagglutination test (rHA). In a part of the trial, EIA was also compared...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1978.tb02902.x
更新日期:1978-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Regulatory T cells (Tregs) and other T-cell subsets are of importance in the setting of autologous and allogeneic stem cell transplantations. We conducted a study to assess the content of peripheral blood stem cell concentrates and related apheresis parameters in the autologous and allogeneic ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12289
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The low prevalence antigen, Be(a), is produced by a complex that also produces weak c, e and f (ce). We report here the molecular basis associated with Be(a) antigen expression. MATERIALS AND METHODS:Peripheral blood samples from four Be(a+) probands were tested. Haemagglutination, gDNA extra...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.2009.01277.x
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to analyse the platelet function, over a 5-day time-period, of apheresis-derived platelet concentrates obtained from smokers and non-smokers. MATERIALS AND METHODS:Smoker and non-smoker plateletpheresis products were investigated on days 1, 3 and 5 of storage. Recept...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.0042-9007.2004.00507.x
更新日期:2004-05-01 00:00:00
abstract::Ocular chronic GVHD is efficaciously treated with autologous platelet-derived eye drops. We investigated the cytokine content of eye drops produced using a non-gelified lysate obtained from autologous platelet-rich plasma in six patients with ocular GVHD. In both the responding (n = 4) and the resistant (n = 2) patien...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12325
更新日期:2016-02-01 00:00:00
abstract::Acute posttransfusion hepatitis C was reported in a recipient of 3 units of red cells. The recipient became acutely icteric 6 weeks after transfusion, and HCV infection was diagnosed. Stored serum samples of the 3 implicated donations, which were negative with ELISA-2, were retested by PCR and 3rd-generation antibody ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1995.tb02546.x
更新日期:1995-01-01 00:00:00
abstract::The thermal stabilization of human albumin by caprylate (CA) and acetyltryptophanate (AT) was studied by monitoring the formation of albumin polymer (defined as species larger than dimer) on the basis of its molecular size as well as its characteristic migration as alpha-globulin. Heating 5% protein solutions of purif...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1984.tb01558.x
更新日期:1984-01-01 00:00:00
abstract::Hepatitis B virus infectivity can be removed from human plasma used to prepare a gamma-globulin product by ion-exchange chromatography with commercially available resins. A pooled human plasma sample free of hepatitis markers was contaminated with 10,000 chimpanzee infectious doses of hepatitis B virus per milliliter ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1985.tb01130.x
更新日期:1985-01-01 00:00:00
abstract::We have studied the IgE content of different lots of commercial intravenous IgG preparations used in our day hospital as replacement therapy for patients with agammaglobulinemia. Two enzymatic methods were used: Phadezym and FAST. The average amounts of IgE detected in Endobulin and Sandoglobulin lots were very high w...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1986.tb00220.x
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Since the first cases of acquired immunodeficiency syndrome in persons with haemophilia were reported in 1982, much has been written about the consequences of human immunodeficiency virus (HIV) contamination of the blood supply. Relatively little attention has been paid to similar hepatitis C virus (HCV) con...
journal_title:Vox sanguinis
pub_type: 历史文章,杂志文章,评审
doi:10.1111/j.1423-0410.2007.00941.x
更新日期:2007-08-01 00:00:00
abstract::Therapeutic antibody removal using antigen-positive red cells was applied to a pregnant woman who has high titered IgG anti-P and had lost all of 4 previous fetuses in P-incompatible pregnancy. The treatment was commenced at the 6th week of gestation and was intensively performed 93 times up to the 35th week. The volu...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1984.tb01589.x
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The Transfusion Requirements In Critical Care (TRICC) study found that critically ill patients tolerate a restrictive haemoglobin transfusion threshold. We investigated red-cell transfusion practice since publication of the TRICC study in a large Scottish teaching hospital intensive care unit ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1046/j.1423-0410.2003.00284.x
更新日期:2003-04-01 00:00:00
abstract::Monocyte-erythrocyte interaction in patients with autoimmune haemolytic anaemia (AIHA) was assessed by phagocytosis and rosette assays. In most patients, a relationship was observed between haemolysis and the phagocytosis of their own erythrocytes by allogenic peripheral monocytes. An evaluation of the number of immun...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1987.tb03030.x
更新日期:1987-01-01 00:00:00
abstract::63 Rh-negative male volunteers were immunized with D-positive red cells. 28 (44%) produced anti-D. To provide sustained levels of high concentration of anti-D, 18 of the 28 male volunteers have received repeated antigenic stimuli at individual intervals of 2-9 months. In all but 1 case the level of anti-D rose to betw...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1978.tb02953.x
更新日期:1978-01-01 00:00:00
abstract::We have used the Optical Character Recognition system B (OCR-B) for automatic identification of blood samples on the Groupamatic 360 and in connection with computerized donor file management and control of blood product processing. For the Groupamatic system a device was constructed that lifts that samples, and during...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:A large number of European blood centres, including our own, use the buffy-coat method for platelet production. In this article we describe a previously unnoticed phenomenon shown by a proportion of buffy-coats, which display an unusually bright cherry colour and low platelet counts. MATERIAL...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1046/j.1423-0410.2001.00005.x
更新日期:2001-01-01 00:00:00
abstract::The storage of fresh frozen plasma (FFP) for short periods at -20 degrees C for 6 weeks, -30 degrees C for 12 weeks, or -40 degrees C for 12 weeks, did not result in significant deterioration in factor VIII: coagulant (factor VIII:C) activity in the primary packs. In studies examining whether plasma segments could be ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1985.tb00174.x
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:The risk of transmitting hepatitis C (HCV) by transfusion of anti-HCV-negative screened blood was estimated for the blood donor population of Baden-Württemberg (southwestern Germany). METHODS:The data from the blood donors screened for anti-HCV and for HBsAg during 1990-1995 were analyzed. RESULTS:The preva...
journal_title:Vox sanguinis
pub_type: 杂志文章,多中心研究
doi:
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Allergic transfusion reactions (ATRs) and febrile non-haemolytic transfusion reactions (FNHTRs) are the two major types of transfusion-related adverse reactions (TRARs). Although prestorage leucocyte reduction and diversion of the first aliquot of blood (LR/D) could reduce FNHTRs and bacterial...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12373
更新日期:2016-05-01 00:00:00
abstract::The international media attention to "bad blood" has fueled governmental action in countries around the world. Donor selection criteria continue to expand, focusing most recently on the possibility of exclusion due to intranasal cocaine use and, in the US, due to incarceration for more than 72 hours. As newer methods ...
journal_title:Vox sanguinis
pub_type: 杂志文章,评审
doi:10.1111/j.1423-0410.1998.tb05465.x
更新日期:1998-01-01 00:00:00
abstract::A 24-hours service was organized to study changes in the hemostatic system in surgical patients undergoing massive transfusion for excessive bleeding during operation or in the early postoperative period. Hemostasis tests gave normal results in only 12(7%) of the 172 patients, while in the remaining 160(93%) one or mo...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1982.tb01080.x
更新日期:1982-03-01 00:00:00
abstract::A red cell IgM autoantibody with anti-e specificity was identified in the serum of a rhesus-negative (rr) patient presenting with haemolytic anaemia and a negative direct antiglobulin test. The autoantibody strongly agglutinated normal allogeneic rhesus-negative (rr) red cells in saline at 37 degrees C but had only we...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1987.tb02993.x
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Transfusion is associated with a risk of infection and alloimmunization. Pathogen reduction using riboflavin and UV light (Mirasol treatment) inactivates pathogens and leucocytes. With increasing adoption of the technology in clinical use, regulatory agencies have recommended the introduction ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12173
更新日期:2014-11-01 00:00:00