Abstract:
:Anti-D levels in blood taken immediately postpartum from Rh-negative women who have been given antenatal Rh immune globulin and the anti-D levels in the cord blood of their babies were measured semiquantitatively by a low ionic polybrene Auto Analyzer technique. When both mother and baby were Rh-negative a comparison of their anti-D levels was made against the interval between injection of the passive anti-D and delivery. Mothers' levels decreased as the interval increased, the regression coefficient for 73 maternal sera was -0.74. The drop in levels of cord blood was much less than that of the mothers' levels. The regression coefficient was -0.294 for 74 cord sera (one set of twins). The marked difference between cord blood and maternal blood levels of anti-D at delivery supports the hypothesis that the transfer of IgG across the placenta is predominantly from mother to fetus and not from fetus to mother.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Pollock JM,Bowman JMdoi
10.1111/j.1423-0410.1982.tb00031.xsubject
Has Abstractpub_date
1982-01-01 00:00:00pages
327-34issue
6eissn
0042-9007issn
1423-0410journal_volume
43pub_type
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